Search Results - "Langer, Manuel"
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Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Published in Journal of medicinal chemistry (12-08-2021)“…We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine…”
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A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
Published in European journal of medicinal chemistry (05-11-2022)“…An amphipathic barbiturate mimic of the marine eusynstyelamides is reported as a promising class of antimicrobial agents. We hereby report a detailed analysis…”
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Investigation of tetrasubstituted heterocycles reveals hydantoins as a promising scaffold for development of novel antimicrobials with membranolytic properties
Published in European journal of medicinal chemistry (05-03-2023)“…Mimics of antimicrobial peptides (AMPs) have been proposed as a promising class of antimicrobial agents. We report the analysis of five tetrasubstituted,…”
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Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
Published in Frontiers in pharmacology (2023)“…The incidence of head and neck squamous cell carcinoma (HNSCC) is increasing and the conventional treatments for this form of cancer can be tough. Despite the…”
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Slope error correction on X-ray reflection gratings by a variation of the local line density
Published in Optics express (19-12-2022)“…The patterning of x-ray grating surfaces by electron-beam lithography offers large flexibility to realize complex optical functionalities. Here, we report on a…”
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Time-resolved visualization of the magnetization canting induced by field-like spin–orbit torques
Published in Applied physics letters (23-11-2020)“…We report on the use of time-resolved scanning transmission x-ray microscopy imaging for the visualization of the dynamical canting of the magnetization…”
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A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
Published in European journal of medicinal chemistry (10-02-2018)“…β-Lactam antibiotics are of utmost importance when treating bacterial infections in the medical community. However, currently their utility is threatened by…”
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Soft x-ray microscopy with 7 nm resolution
Published in Optica (20-11-2020)“…The availability of intense soft x-ray beams with tunable energy and polarization has pushed the development of highly sensitive, element-specific, and…”
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Current-induced dynamical tilting of chiral domain walls in curved microwires
Published in Applied physics letters (04-05-2020)“…We report on the investigation of current-induced domain wall motion of Néel domain walls in perpendicularly magnetized microwires with curved geometries in…”
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Multifocus off-axis zone plates for x-ray free-electron laser experiments
Published in Optica (20-08-2020)“…X-ray free-electron lasers (XFELs) are paving the way towards new experiments in many scientific fields, such as ultrafast science, nonlinear spectroscopy, and…”
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Ultra-dense planar metallic nanowire arrays with extremely large anisotropic optical and magnetic properties
Published in Nano research (01-07-2018)“…A nanofabrication method for the production of ultra-dense planar metallic nanowire arrays scalable to wafer-size is presented. The method is based on an…”
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Programmability of Co-antidot lattices of optimized geometry
Published in Scientific reports (01-02-2017)“…Programmability of stable magnetization configurations in a magnetic device is a highly desirable feature for a variety of applications, such as in…”
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Symmetry and localization properties of defect modes in magnonic superlattices
Published 03-12-2018“…Physical Review B 97, 174404 (2018) Symmetry and localization properties of defect modes of a one-dimensional bi-component magnonic superlattice are…”
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Spin-Wave Modes in Transition from a Thin Film to a Full Magnonic Crystal
Published 18-12-2018“…Phys. Rev. B 99, 024426 (2019) Spin-wave modes are studied under the gradual transition from a flat thin film to a 'full' (one-dimensional) magnonic crystal…”
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Both Urinary Excreted Melatonin and 6-Hydroxy-Melatonin Sulfate Are Good Representatives of Endogenous Serum Melatonin Concentration in Human
Published in Pediatric research (01-04-1999)Get full text
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The role of the internal demagnetizing field in a surface-modulated magnonic crystal
Published 20-10-2016“…Phys. Rev. B 95, 184405 (2017) Magnonic crystals with locally alternating properties and specific periodicities exhibit interesting effects, such as a…”
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