Search Results - "Langer, Ingrid"

Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors by Langer, Ingrid, Latek, Dorota

“…Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two neuropeptides that contribute to the regulation of…”
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Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor by Peyrassol, Xavier, Laeremans, Toon, Gouwy, Mieke, Lahura, Vannessa, Debulpaep, Maja, Van Damme, Jo, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid

“…The generation of Abs that recognize the native conformation of G protein-coupled receptors can be a challenging task because, like most multimembrane-spanning…”
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Signal Transduction by VIP and PACAP Receptors by Langer, Ingrid, Jeandriens, Jérôme, Couvineau, Alain, Sanmukh, Swapnil, Latek, Dorota

“…Homeostasis of the human immune system is regulated by many cellular components, including two neuropeptides, VIP and PACAP, primary stimuli for three class B…”
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Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells by Estienne, Anthony, Mellouk, Namya, Bongrani, Alice, Plotton, Ingrid, Langer, Ingrid, Ramé, Christelle, Petit, Claire, Guérif, Fabrice, Froment, Pascal, Dupont, Joëlle

“…Polycystic ovarian syndrome (PCOS) is the main cause of infertility in women. It is frequently associated with reduced progesterone production by human…”
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A Molecular Dynamics Study of Vasoactive Intestinal Peptide Receptor 1 and the Basis of Its Therapeutic Antagonism by Latek, Dorota, Langer, Ingrid, Krzysko, Krystiana, Charzewski, Lukasz

“…Vasoactive intestinal peptide receptor 1 (VPAC1) is a member of a secretin-like subfamily of G protein-coupled receptors. Its endogenous neuropeptide (VIP),…”
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Flavonoids and strigolactones in root exudates as signals in symbiotic and pathogenic plant-fungus interactions by Steinkellner, Siegrid, Lendzemo, Venasius, Langer, Ingrid, Schweiger, Peter, Khaosaad, Thanasan, Toussaint, Jean-Patrick, Vierheilig, Horst

“…Secondary plant compounds are important signals in several symbiotic and pathogenic plant-microbe interactions. The present review is limited to two groups of…”
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Mechanisms involved in VPAC receptors activation and regulation: lessons from pharmacological and mutagenesis studies by Langer, Ingrid

“…Vasoactive intestinal peptide (VIP) plays diverse and important role in human physiology and physiopathology and their receptors constitute potential targets…”
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Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function by Peyrassol, Xavier, Laeremans, Toon, Lahura, Vannessa, Debulpaep, Maja, El Hassan, Hassan, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid

“…Multi-membrane spanning proteins, such as G protein-coupled receptors (GPCRs) and ion channels, are extremely difficult to purify as native proteins…”
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Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G‑Protein Coupled Receptor Expression by Claes, Katrien, Vandewalle, Kristof, Laukens, Bram, Laeremans, Toon, Vosters, Olivier, Langer, Ingrid, Parmentier, Marc, Steyaert, Jan, Callewaert, Nico

“…Membrane protein research is still hampered by the generally very low levels at which these proteins are naturally expressed, necessitating heterologous…”
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Mechanism of Activation of a G Protein-coupled Receptor, the Human Cholecystokinin-2 Receptor by Marco, Esther, Foucaud, Magali, Langer, Ingrid, Escrieut, Chantal, Tikhonova, Irina G., Fourmy, Daniel

“…G protein-coupled receptors (GPCRs) represent a major focus in functional genomics programs and drug development research, but their important potential as…”
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Evidence for a direct and functional interaction between the regulators of G protein signaling-2 and phosphorylated C terminus of cholecystokinin-2 receptor by Langer, Ingrid, Tikhonova, Irina G, Boulègue, Cyril, Estève, Jean-Pierre, Vatinel, Sébastien, Ferrand, Audrey, Moroder, Luis, Robberecht, Patrick, Fourmy, Daniel

“…Signaling of G protein-coupled receptors (GPCRs) is regulated by different mechanisms. One of these involves regulators of G protein signaling (RGS), which are…”
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Media formulation influences in vitro ectomycorrhizal synthesis on the European aspen Populus tremula L by Langer, Ingrid, Krpata, Doris, Peintner, Ursula, Wenzel, Walter W, Schweiger, Peter

“…The effect of various media formulations on in vitro ectomycorrhizal synthesis of identified fungal strains with European aspen (Populus tremula L.) was tested…”
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Contribution of the Carboxyl Terminus of the VPAC1 Receptor to Agonist-induced Receptor Phosphorylation, Internalization, and Recycling by Langlet, Christelle, Langer, Ingrid, Vertongen, Pascale, Gaspard, Nathalie, Vanderwinden, Jean-Marie, Robberecht, Patrick

“…When exposed to vasoactive intestinal peptide (VIP), the human wild type VPAC1 receptor expressed in Chinese hamster ovary (CHO) cells is rapidly…”
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Effect of inactivating mutations on phosphorylation and internalization of the human VPAC2 receptor by Langer, Ingrid, Langlet, Christelle, Robberecht, Patrick

“…The VPAC2 receptor, as all members of the G-protein-coupled receptor (GPCR)-B family, has two highly conserved motifs in the third intracellular (IC3) loop: a…”
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Two Basic Residues of the h-VPAC1 Receptor Second Transmembrane Helix Are Essential for Ligand Binding and Signal Transduction by Solano, Rosa Maria, Langer, Ingrid, Perret, Jason, Vertongen, Pascale, Juarranz, Maria Guillerma, Robberecht, Patrick, Waelbroeck, Magali

“…We mutated the vasoactive intestinal peptide (VIP) Asp3 residue and two VPAC1receptor second transmembrane helix basic residues (Arg188and Lys195). VIP had a…”
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Impact of tillage on the incidence ofFusarium spp. in soil by Steinkellner, Siegrid, Langer, Ingrid

“…The influence of several long-term conventional and conservation tillage treatments on the incidence and the diversity ofFusarium spp. in soil was studied…”
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In memoriam - Patrick Robberecht (1944–2023) by Couvineau, Alain, Moratilla, Yasmina Juarranz, Langer, Ingrid

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Conformational switches in the VPAC1 receptor by Langer, Ingrid

“…The vasoactive intestinal peptide receptor 1 (VPAC1) belongs to family B of GPCRs and is activated upon binding of vasoactive intestinal peptide (VIP) and…”
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Evidence That Interspecies Polymorphism in the Human and Rat Cholecystokinin Receptor-2 Affects Structure of the Binding Site for the Endogenous Agonist Cholecystokinin by Langer, Ingrid, Tikhonova, Irina G., Travers, Marie-Agnès, Archer-Lahlou, Elodie, Escrieut, Chantal, Maigret, Bernard, Fourmy, Daniel

“…The cholecystokinin (CCK) receptor-2 exerts very important central and peripheral functions by binding the neuropeptides cholecystokinin or gastrin. Because…”
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Conformational switches in the VPAC 1 receptor by Langer, Ingrid

“…The vasoactive intestinal peptide receptor 1 (VPAC 1 ) belongs to family B of GPCRs and is activated upon binding of vasoactive intestinal peptide (VIP) and…”
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