Search Results - "Langenbach, R"
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1
Why there are two cyclooxygenase isozymes
Published in The Journal of clinical investigation (01-06-2001)Get full text
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Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice
Published in Cardiovascular research (2007)“…Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammation which contributes to the remodeling and eventual weakening of the vessel wall…”
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3
Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in min mice
Published in Cancer research (Chicago, Ill.) (01-09-2000)“…Two isoforms of cyclooxygenase (COX) are known, and to date most studies have implicated COX-2, rather than COX-1, as the isoform involved in colon…”
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4
Mesh fixation in open IPOM procedure with tackers or sutures? A randomized clinical trial with preliminary results
Published in Hernia : the journal of hernias and abdominal wall surgery (01-02-2020)“…Purpose In open intra-peritoneal onlay mesh (IPOM) hernia repair, mesh fixation can be done by tacks, sutures or fibrin glue. There are randomized controlled…”
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5
Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra
Published in Neuroscience letters (06-09-2002)“…Cyclooxygenases (COX), key enzymes in prostanoid biosynthesis, may represent important therapeutic targets in various neurodegenerative diseases. In the…”
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6
Comparison of biomaterials : three meshes and TAPP for inguinal hernia
Published in Surgical endoscopy (01-10-2006)“…In laparoscopic hernia repair the use of biocompatible materials is necessary. A prospective, double-blind study was projected to compare three different…”
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Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
Published in Cell (03-11-1995)“…Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely used nonsteroidal…”
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Randomized sham-controlled trial of acupuncture for postoperative pain control after stapled haemorrhoidopexy
Published in Colorectal disease (01-08-2012)“…Aim Haemorrhoidectomy usually causes moderate to strong postoperative pain. Chinese studies have found that acupuncture may have an analgesic effect in…”
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9
Independency of myocardial stunning of endothelial stunning?
Published in Basic research in cardiology (01-07-2007)“…Vascular endothelial cells play an important role in the control of vascular tone. The reasons for coronary endothelial dysfunction are complex and may involve…”
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10
The prostaglandin receptor EP2 activates multiple signaling pathways and -arrestin1 complex formation during mouse skin papilloma development
Published in Carcinogenesis (New York) (01-09-2009)“…Prostaglandin E[sub]2 (PGE[sub]2) is elevated in many tumor types, but PGE[sub]2's contributions to tumor growth are largely unknown. To investigate…”
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Airway Inflammation and Responsiveness in Prostaglandin H Synthase-Deficient Mice Exposed to Bacterial Lipopolysaccharide
Published in American journal of respiratory cell and molecular biology (01-10-2001)“…Bacterial lipopolysaccharide (LPS) is a risk factor for exacerbation of asthma and causes airway inflammation. The aim of this study was to examine the effects…”
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Comparison of biomaterials in the early postoperative period: Polypropylene meshes in laparoscopic inguinal hernia repair
Published in Surgical endoscopy (01-07-2003)Get full text
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13
External prolapse of the rectum: stapled prolapse resection, not only for older and frail patients
Published in Minerva chirurgica (01-08-2017)“…The perineal stapler prolapse resection (PSP-resection) was introduced in 2008 as an option to treat the external prolapse of the rectum, especially for older,…”
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14
Leukocyte Lipid Body Formation and Eicosanoid Generation: Cyclooxygenase-Independent Inhibition by Aspirin
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1996)“…Lipid bodies, cytoplasmic inclusions that develop in cells associated with inflammation, are inducible structures that might participate in generating…”
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15
Evidence for palliative enlargement of the right ventricular outflow tract in severe tetralogy of Fallot
Published in European journal of cardio-thoracic surgery (01-06-2005)“…Objective: If the pulmonary artery (PA) tree in patients with Fallot's tetralogy (TOF) is extremely hypoplastic, a shunt procedure may be difficult and not…”
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Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy
Published in Molecular and Cellular Biology (01-10-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cyclooxygenase knockout mice: Models for elucidating isoform-specific functions
Published in Biochemical pharmacology (15-10-1999)“…The development of cyclooxygenase (COX) deficient mice has allowed investigation into the individual physiological roles of the COX-1 and COX-2 isoforms. In…”
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Role of reactive oxygen species in LPS‐induced production of prostaglandin E 2 in microglia
Published in Journal of neurochemistry (01-02-2004)“…Abstract We determined the roles of reactive oxygen species (ROS) in the expression of cyclooxygenase‐2 (COX‐2) and the production of prostaglandin E 2 (PGE 2…”
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Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-06-2002)“…Nonsteroidal anti-inflammatory drugs are widely reported to inhibit carcinogenesis in humans and in rodents. These drugs are believed to act by inhibiting one…”
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Development of a human cell line by selection and drug-metabolizing gene transfection with increased capacity to activate promutagens
Published in Carcinogenesis (New York) (01-05-1989)“…We have isolated a human lymphoblastoid cell line with higher levels of native cytochrome P450IA1 activity and by DNA transfection introduced human cDNAs for a…”
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