Search Results - "Langen, Ramon CJ"

Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation by Leermakers, Pieter A., Kneppers, Anita E.M., Schols, Annemie M.W.J., Kelders, Marco C.J.M., Theije, Chiel C., Verdijk, Lex B., Loon, Luc J.C., Langen, Ramon C.J., Gosker, Harry R.

“…Introduction Physical inactivity significantly contributes to loss of muscle mass and performance in bed‐bound patients. Loss of skeletal muscle mitochondrial…”
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Distinct responses of protein turnover regulatory pathways in hypoxia- and semistarvation-induced muscle atrophy by de Theije, Chiel C, Langen, Ramon C J, Lamers, Wouter H, Schols, Annemie M W J, Köhler, S Eleonore

“…The balance of muscle protein synthesis and degradation determines skeletal muscle mass. We hypothesized that hypoxia-induced muscle atrophy and alterations in…”
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Glycogen Synthase Kinase 3β Suppresses Myogenic Differentiation through Negative Regulation of NFATc3 by van der Velden, Jos L.J., Schols, Annemie M.W.J., Willems, Jodil, Kelders, Marco C.J.M., Langen, Ramon C.J.

“…Skeletal muscle atrophy is a prominent and disabling feature in many chronic diseases. Prevention or reversal of muscle atrophy by stimulation of skeletal…”
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Preferential stimulation of myofibrillar proteins by amino acids in absence of increased mTORC1 signaling by Haegens, Astrid, Schols, Annemie M, Essen, Anon LM, Loon, Luc JC, Langen, Ramon CJ

“…An important goal of nutritional intervention in muscle wasting disorders is to stimulate protein synthesis. Branched chain amino acids (AA) have been…”
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Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy by Verhees, Koen J P, Pansters, Nicholas A M, Baarsma, Hoeke A, Remels, Alexander H V, Haegens, Astrid, de Theije, Chiel C, Schols, Annemie M W J, Gosens, Reinoud, Langen, Ramon C J

“…Chronic obstructive pulmonary disease (COPD) is accompanied by pulmonary inflammation and associated with extra-pulmonary manifestations, including skeletal…”
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Preserved muscle oxidative metabolic phenotype in newly diagnosed non‐small cell lung cancer cachexia by Op den Kamp, Celine M., Gosker, Harry R., Lagarde, Suzanne, Tan, Daniel Y., Snepvangers, Frank J., Dingemans, Anne‐Marie C., Langen, Ramon C.J., Schols, Annemie M.W.J.

“…Background Cachexia augments cancer‐related mortality and has devastating effects on quality of life. Pre‐clinical studies indicate that systemic…”
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Inflammatory signaling in skeletal muscle insulin resistance: green signal for nutritional intervention? by Hommelberg, Pascal PH, Langen, Ramon CJ, Schols, Annemie MWJ, Mensink, Ronald P, Plat, Jogchum

“…PURPOSE OF REVIEWTo review the evidence implying a role of inflammatory signaling pathways, specifically nuclear factor-κB and c-Jun NH2-terminal kinase, in…”
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Postprandial increase in AA plasma levels are sufficient to stimulate muscle specific and total protein accretion in vitro by Haegens, Astrid, Schols, Annemie M, Pennings, Bart, Essen, Anon LM, Loon, Luc JC, Langen, Ramon CJ

“…Skeletal muscle cell lines have been applied to model muscle growth in vitro. In this study we investigated whether specific amino acids (AA), at…”
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ENHANCED MYOGENIC DIFFERENTIATION BY EXTRACELLULAR MATRIX IS REGULATED AT THE EARLY STAGES OF MYOGENESIS by LANGEN, RAMON C. J, SCHOLS, ANNEMIE M. W. J, KELDERS, MARCO C. J. M, WOUTERS, EMIEL F. M, JANSSEN-HEININGER, YVONNE M. W

“…Myogenic cell lines have been used extensively in the study of skeletal muscle development, regeneration, and homeostasis. To induce myogenic differentiation,…”
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