Search Results - "Langen, Karl Josef"

Comparison of EEG microstates with resting state fMRI and FDG‐PET measures in the default mode network via simultaneously recorded trimodal (PET/MR/EEG) data by Rajkumar, Ravichandran, Farrher, Ezequiel, Mauler, Jörg, Sripad, Praveen, Régio Brambilla, Cláudia, Rota Kops, Elena, Scheins, Jürgen, Dammers, Jürgen, Lerche, Christoph, Langen, Karl‐Josef, Herzog, Hans, Biswal, Bharat, Shah, N. Jon, Neuner, Irene

“…Simultaneous trimodal positron emission tomography/magnetic resonance imaging/electroencephalography (PET/MRI/EEG) resting state (rs) brain data were acquired…”
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Contribution of PET imaging to radiotherapy planning and monitoring in glioma patients - a report of the PET/RANO group by Galldiks, Norbert, Niyazi, Maximilian, Grosu, Anca L, Kocher, Martin, Langen, Karl-Josef, Law, Ian, Minniti, Giuseppe, Kim, Michelle M, Tsien, Christina, Dhermain, Frederic, Soffietti, Riccardo, Mehta, Minesh P, Weller, Michael, Tonn, Jörg-Christian

“…Abstract The management of patients with glioma usually requires multimodality treatment including surgery, radiotherapy, and systemic therapy. Accurate…”
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Relaxometry and quantification in sodium MRI of cerebral gliomas: A FET‐PET and MRI small‐scale study by Worthoff, Wieland A., Shymanskaya, Aliaksandra, Lindemeyer, Johannes, Langen, Karl‐Josef, Shah, N. Jon

“…Sodium MRI is a promising method for assessing the metabolic properties of brain tumours. In a recent study, a strong relationship between semi‐quantitative…”
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Protease Responsive Nanogels for Transcytosis across the Blood−Brain Barrier and Intracellular Delivery of Radiopharmaceuticals to Brain Tumor Cells by Singh, Smriti, Drude, Natascha, Blank, Lena, Desai, Prachi Bharat, Königs, Hiltrud, Rütten, Stephan, Langen, Karl‐Josef, Möller, Martin, Mottaghy, Felix M., Morgenroth, Agnieszka

“…Despite profound advances in treatment approaches, gliomas remain associated with very poor prognoses. The residual cells after incomplete resection often…”
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Imaging of sodium in the brain: a brief review by Shah, N. Jon, Worthoff, Wieland A., Langen, Karl-Josef

“…Sodium‐based MRI plays a vital role in the study of metabolism and can unveil valuable information about emerging and existing pathology – in particular in the…”
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mGluR5 receptor availability is associated with lower levels of negative symptoms and better cognition in male patients with chronic schizophrenia by Régio Brambilla, Cláudia, Veselinović, Tanja, Rajkumar, Ravichandran, Mauler, Jörg, Orth, Linda, Ruch, Andrej, Ramkiran, Shukti, Heekeren, Karsten, Kawohl, Wolfram, Wyss, Christine, Kops, Elena Rota, Scheins, Jürgen, Tellmann, Lutz, Boers, Frank, Neumaier, Bernd, Ermert, Johannes, Herzog, Hans, Langen, Karl‐Josef, Jon Shah, N., Lerche, Christoph, Neuner, Irene

“…Consistent findings postulate disturbed glutamatergic function (more specifically a hypofunction of the ionotropic NMDA receptors) as an important…”
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Current Landscape and Emerging Fields of PET Imaging in Patients with Brain Tumors by Werner, Jan-Michael, Lohmann, Philipp, Fink, Gereon R, Langen, Karl-Josef, Galldiks, Norbert

“…The number of positron-emission tomography (PET) tracers used to evaluate patients with brain tumors has increased substantially over the last years. For the…”
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Predicting IDH genotype in gliomas using FET PET radiomics by Lohmann, Philipp, Lerche, Christoph, Bauer, Elena K., Steger, Jan, Stoffels, Gabriele, Blau, Tobias, Dunkl, Veronika, Kocher, Martin, Viswanathan, Shivakumar, Filss, Christian P., Stegmayr, Carina, Ruge, Maximillian I., Neumaier, Bernd, Shah, Nadim J., Fink, Gereon R., Langen, Karl-Josef, Galldiks, Norbert

“…Mutations in the isocitrate dehydrogenase (IDH mut) gene have gained paramount importance for the prognosis of glioma patients. To date, reliable techniques…”
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Sequential implementation of DSC-MR perfusion and dynamic [18F]FET PET allows efficient differentiation of glioma progression from treatment-related changes by Steidl, Eike, Langen, Karl-Josef, Hmeidan, Sarah Abu, Polomac, Nenad, Filss, Christian P., Galldiks, Norbert, Lohmann, Philipp, Keil, Fee, Filipski, Katharina, Mottaghy, Felix M., Shah, Nadim Jon, Steinbach, Joachim P., Hattingen, Elke, Maurer, Gabriele D.

“…Purpose Perfusion-weighted MRI (PWI) and O-(2-[ 18 F]fluoroethyl-)- l -tyrosine ([ 18 F]FET) PET are both applied to discriminate tumor progression (TP) from…”
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Use of advanced neuroimaging and artificial intelligence in meningiomas by Galldiks, Norbert, Angenstein, Frank, Werner, Jan‐Michael, Bauer, Elena K., Gutsche, Robin, Fink, Gereon R., Langen, Karl‐Josef, Lohmann, Philipp

“…Anatomical cross‐sectional imaging methods such as contrast‐enhanced MRI and CT are the standard for the delineation, treatment planning, and follow‐up of…”
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The use of amino acid PET and conventional MRI for monitoring of brain tumor therapy by Galldiks, Norbert, Law, Ian, Pope, Whitney B, Arbizu, Javier, Langen, Karl-Josef

“…Routine diagnostics and treatment monitoring of brain tumors is usually based on contrast-enhanced MRI. However, the capacity of conventional MRI to…”
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Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study by Liu, Jingjin, Nolte, Kay, Brook, Gary, Liebenstund, Lisa, Weinandy, Agnieszka, Höllig, Anke, Veldeman, Michael, Willuweit, Antje, Langen, Karl-Josef, Rossaint, Rolf, Coburn, Mark

“…In recent years, argon has been shown to exert neuroprotective effects in an array of models. However, the mechanisms by which argon exerts its neuroprotective…”
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Post-stroke treatment with argon preserved neurons and attenuated microglia/macrophage activation long-termly in a rat model of transient middle cerebral artery occlusion (tMCAO) by Liu, Jingjin, Veldeman, Michael, Höllig, Anke, Nolte, Kay, Liebenstund, Lisa, Willuweit, Antje, Langen, Karl-Josef, Rossaint, Rolf, Coburn, Mark

“…In a previous study from our group, argon has shown to significantly attenuate brain injury, reduce brain inflammation and enhance M 2 microglia/macrophage…”
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Investigational PET tracers in neuro-oncology-What's on the horizon? A report of the PET/RANO group by Galldiks, Norbert, Langen, Karl-Josef, Albert, Nathalie L, Law, Ian, Kim, Michelle M, Villanueva-Meyer, Javier E, Soffietti, Riccardo, Wen, Patrick Y, Weller, Michael, Tonn, Joerg C

“…Many studies in patients with brain tumors evaluating innovative PET tracers have been published in recent years, and the initial results are promising. Here,…”
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Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis by Lohmann, Philipp, Kocher, Martin, Ceccon, Garry, Bauer, Elena K., Stoffels, Gabriele, Viswanathan, Shivakumar, Ruge, Maximilian I., Neumaier, Bernd, Shah, Nadim J., Fink, Gereon R., Langen, Karl-Josef, Galldiks, Norbert

“…The aim of this study was to investigate the potential of combined textural feature analysis of contrast-enhanced MRI (CE-MRI) and static…”
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Brain Tumors by Herholz, Karl, MD, Langen, Karl-Josef, MD, Schiepers, Christiaan, MD, PhD, Mountz, James M., MD, PhD

“…This review addresses the specific contributions of nuclear medicine techniques, and especially positron emission tomography (PET), for diagnosis and…”
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Role of O -(2- 18 F-Fluoroethyl)-l-Tyrosine PET for Differentiation of Local Recurrent Brain Metastasis from Radiation Necrosis by Galldiks, Norbert, Stoffels, Gabriele, Filss, Christian P., Piroth, Marc D., Sabel, Michael, Ruge, Maximilian I., Herzog, Hans, Shah, Nadim J., Fink, Gereon R., Coenen, Heinz H., Langen, Karl-Josef

“…The aim of this study was to investigate the potential of O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis…”
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Prognostic value of pre-irradiation FET PET in patients with not completely resectable IDH-wildtype glioma and minimal or absent contrast enhancement by Rosen, Jurij, Stoffels, Gabriele, Lohmann, Philipp, Bauer, Elena K., Werner, Jan-Michael, Wollring, Michael, Rapp, Marion, Felsberg, Jörg, Kocher, Martin, Fink, Gereon R., Langen, Karl-Josef, Galldiks, Norbert

“…In glioma patients, complete resection of the contrast-enhancing portion is associated with improved survival, which, however, cannot be achieved in a…”
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Amino Acid PET - An Imaging Option to Identify Treatment Response, Posttherapeutic Effects, and Tumor Recurrence? by Galldiks, Norbert, Langen, Karl-Josef

“…Routine diagnostics and treatment monitoring in patients with primary and secondary brain tumors is usually based on contrast-enhanced standard MRI. However,…”
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Current trends in the use of O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) in neurooncology by Stegmayr, Carina, Stoffels, Gabriele, Filß, Christian, Heinzel, Alexander, Lohmann, Philipp, Willuweit, Antje, Ermert, Johannes, Coenen, Heinz H., Mottaghy, Felix M., Galldiks, Norbert, Langen, Karl-Josef

“…The diagnostic potential of PET using the amino acid analogue O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) in brain tumor diagnostics has been proven in many…”
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