Search Results - "Langen, J."

Bone regeneration induced by a 3D architectured hydrogel in a rat critical-size calvarial defect by Lohmann, P, Willuweit, A, Neffe, A.T, Geisler, S, Gebauer, T.P, Beer, S, Coenen, H.H, Fischer, H, Hermanns-Sachweh, B, Lendlein, A, Shah, N.J, Kiessling, F, Langen, K.-J

“…Abstract Bone regeneration can be stimulated by implantation of biomaterials, which is especially important for larger bone defects. Here, healing potency of…”
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Inflammation and Skeletal Muscle Wasting During Cachexia by Webster, Justine M, Kempen, Laura J A P, Hardy, Rowan S, Langen, Ramon C J

“…Cachexia is the involuntary loss of muscle and adipose tissue that strongly affects mortality and treatment efficacy in patients with cancer or chronic…”
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Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer by Niemeijer, A. N., Leung, D., Huisman, M. C., Bahce, I., Hoekstra, O. S., van Dongen, G. A. M. S., Boellaard, R., Du, S., Hayes, W., Smith, R., Windhorst, A. D., Hendrikse, N. H., Poot, A., Vugts, D. J., Thunnissen, E., Morin, P., Lipovsek, D., Donnelly, D. J., Bonacorsi, S. J., Velasquez, L. M., de Gruijl, T. D., Smit, E. F., de Langen, A. J.

“…PD-L1 immunohistochemistry correlates only moderately with patient survival and response to PD-(L)1 treatment. Heterogeneity of tumor PD-L1 expression might…”
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The mechanisms of cachexia underlying muscle dysfunction in COPD by Remels, A H V, Gosker, H R, Langen, R C J, Schols, A M W J

“…Pulmonary cachexia is a prevalent, debilitating, and well-recognized feature of COPD associated with increased mortality and loss of peripheral and respiratory…”
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Repeatability of Radiomic Features in Non-Small-Cell Lung Cancer [18F]FDG-PET/CT Studies: Impact of Reconstruction and Delineation by van Velden, Floris H. P., Kramer, Gerbrand M., Frings, Virginie, Nissen, Ida A., Mulder, Emma R., de Langen, Adrianus J., Hoekstra, Otto S., Smit, Egbert F., Boellaard, Ronald

“…Purpose To assess (1) the repeatability and (2) the impact of reconstruction methods and delineation on the repeatability of 105 radiomic features in…”
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MIPAS: an instrument for atmospheric and climate research by Fischer, H., Birk, M., Blom, C., Carli, B., Carlotti, M., von Clarmann, T., Delbouille, L., Dudhia, A., Ehhalt, D., Endemann, M., Flaud, J. M., Gessner, R., Kleinert, A., Koopman, R., Langen, J., López-Puertas, M., Mosner, P., Nett, H., Oelhaf, H., Perron, G., Remedios, J., Ridolfi, M., Stiller, G., Zander, R.

“…MIPAS, the Michelson Interferometer for Passive Atmospheric Sounding, is a mid-infrared emission spectrometer which is part of the core payload of ENVISAT. It…”
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Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI by da Silva, N. A., Lohmann, P., Fairney, J., Magill, A. W., Oros Peusquens, A.-M., Choi, C.-H., Stirnberg, R., Stoffels, G., Galldiks, N., Golay, X., Langen, K.-J., Jon Shah, N.

“…Purpose PET using radiolabelled amino acids has become a promising tool in the diagnostics of gliomas and brain metastasis. Current research is focused on the…”
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Applications of PET imaging of neurological tumors with radiolabeled amino acids by Galldiks, N, Langen, K J

“…Routine diagnostics and treatment monitoring of brain tumors is usually based on contrast-enhanced magnetic resonance imaging (MRI). However, the capacity of…”
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Hidden in plain sight: how individual ADHD stakeholders have conflicting ideas about ADHD but do not address their own ambivalence by van Langen, Myrte J. M., van Hulst, Branko M., Durston, Sarah

“…Psychiatric classifications refer to clusters of behavioral symptoms. We know much about how psychiatric classifications are intended to be used in theory. Yet…”
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Multicenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations by Koopman, Bart, Groen, Harry J.M., Ligtenberg, Marjolijn J.L., Grünberg, Katrien, Monkhorst, Kim, Langen, Adrianus J., Boelens, Mirjam C., Paats, Marthe S., Thüsen, Jan H., Dinjens, Winand N.M., Solleveld, Nienke, Wezel, Tom, Gelderblom, Hans, Hendriks, Lizza E., Speel, Ernst‐Jan M., Theunissen, Tom E., Kroeze, Leonie I., Mehra, Niven, Piet, Berber, Wekken, Anthonie J., Elst, Arja, Timens, Wim, Willems, Stefan M., Meijers, Ruud W.J., Leng, Wendy W.J., Lindert, Anne S.R., Radonic, Teodora, Hashemi, Sayed M.S., Heideman, Daniëlle A.M., Schuuring, Ed, Kempen, Léon C.

“…Background Molecular tumor boards (MTBs) provide rational, genomics‐driven, patient‐tailored treatment recommendations. Worldwide, MTBs differ in terms of…”
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Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting by Boosman, René J., Jebbink, Merel, Veldhuis, Wouter B., Groenland, Stefanie L., van Veggel, Bianca A. M. H., Moeskops, Pim, de Langen, Adrianus J., Beijnen, Jos H., Smit, Egbert F., Huitema, Alwin D. R., Steeghs, Neeltje

“…Background Osimertinib, an irreversible inhibitor of the epidermal growth factor receptor (EGFR) is an important drug in the treatment of EGFR-mutation…”
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Lost in explanation: internal conflicts in the discourse of ADHD psychoeducation by van Langen, Myrte J M, Szőke, Rebeka, Rijkelijkhuizen, Dominique N J, Durston, Sarah, van Hulst, Branko M

“…Psychiatric classifications are understood in many different ways. For children with ADHD and their parents, psychoeducation is an important source of…”
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Feasibility of whole‐genome sequencing‐based tumor diagnostics in routine pathology practice by Samsom, Kris G, Schipper, Luuk J, Roepman, Paul, Bosch, Linda JW, Lalezari, Ferry, Klompenhouwer, Elisabeth G, Langen, Adrianus J, Buffart, Tineke E, Riethorst, Immy, Schoenmaker, Lieke, Schout, Daoin, Noort, Vincent, Berg, Jose G, Bruijn, Ewart, Hoeven, Jacobus JM, Snellenberg, Hans, Kolk, Lizet E, Cuppen, Edwin, Voest, Emile E, Meijer, Gerrit A, Monkhorst, Kim

“…The current increase in number and diversity of targeted anticancer agents poses challenges to the logistics and timeliness of molecular diagnostics (MolDx),…”
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A phase 2 trial combining afatinib with cetuximab in patients with EGFR exon 20 insertion–positive non–small cell lung cancer by Veggel, Bianca A. M. H., Wekken, Anthonie J., Paats, Marthe S., Hendriks, Lizza E. L., Hashemi, Sayed M. S., Daletzakis, Antonios, Broek, Daan, Bosch, Linda J. W., Monkhorst, Kim, Smit, Egbert F., Langen, Adrianus J.

“…Background Epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations are the third most common EGFR mutations in patients with non–small…”
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Clinical Relevance of High Plasma Trough Levels of the Kinase Inhibitors Crizotinib, Alectinib, Osimertinib, Dabrafenib, and Trametinib in NSCLC Patients by Lin, Lishi, Barkman, Hannerieke J., Smit, Egbert F., de Langen, Adrianus J., Steeghs, Neeltje, Beijnen, Jos H., Huitema, Alwin D. R.

“…the study aims to evaluate whether high plasma trough levels of the kinase inhibitors (K.I.s) crizotinib, alectinib, osimertinib, dabrafenib, and trametinib…”
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Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy by de Theije, C C, Schols, A M W J, Lamers, W H, Neumann, D, Köhler, S E, Langen, R C J

“…Hypoxemia in humans may occur during high altitude mountaineering and in patients suffering from ventilatory insufficiencies such as cardiovascular- or…”
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Targeted nutritional intervention attenuates experimental lung cancer cachexia by Worp, Wouter R. P. H., Theys, Jan, Wolfs, Cecile J. A., Verhaegen, Frank, Schols, Annemie M. W. J., Helvoort, Ardy, Langen, Ramon C. J.

“…Background Cachexia, a syndrome with high prevalence in non‐small cell lung cancer patients, impairs quality of life and reduces tolerance and responsiveness…”
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Prognostic Value of Early [18 F]Fluoroethyltyrosine Positron Emission Tomography After Radiochemotherapy in Glioblastoma Multiforme by Piroth, Marc D., M.D, Pinkawa, Michael, M.D, Holy, Richard, M.D, Klotz, Jens, M.D, Nussen, Sandra, M.D, Stoffels, Gabriele, M.D, Coenen, Heinz H., Ph.D, Kaiser, Hans J., Ph.D, Langen, Karl J., M.D, Eble, Michael J., M.D

“…Purpose Early detection of treatment response in glioma patients after radiochemotherapy (RCX) is uncertain because treatment-related contrast enhancement in…”
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Evaluation of the Sensitivity of Metabolic Profiling by Rapid Evaporative Ionization Mass Spectrometry: Toward More Radical Oral Cavity Cancer Resections by Vaysse, Pierre-Maxence, Demers, Imke, van den Hout, Mari F. C. M., van de Worp, Wouter, Anthony, Ian G. M., Baijens, Laura W. J., Tan, Bing I., Lacko, Martin, Vaassen, Lauretta A. A., van Mierlo, Auke, Langen, Ramon C. J., Speel, Ernst-Jan M., Heeren, Ron M. A., Porta Siegel, Tiffany, Kremer, Bernd

“…Radical resection for patients with oral cavity cancer remains challenging. Rapid evaporative ionization mass spectrometry (REIMS) of electrosurgical vapors…”
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Cachexia in chronic obstructive pulmonary disease: new insights and therapeutic perspective by Sanders, Karin J. C., Kneppers, Anita E. M., Bool, Coby, Langen, Ramon C. J., Schols, Annemie M. W. J.

“…Cachexia and muscle wasting are well recognized as common and partly reversible features of chronic obstructive pulmonary disease (COPD), adversely affecting…”
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