Search Results - "Langella, P."

Faecalibacterium prausnitzii and human intestinal health by Miquel, S, Martín, R, Rossi, O, Bermúdez-Humarán, LG, Chatel, JM, Sokol, H, Thomas, M, Wells, JM, Langella, P

“…Highlights • Faecalibacterium prausnitzii is an ubiquitary bacterium of intestinal microbiota of all animals. • F. prausnitzii is a dominant member of human…”
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Display of recombinant proteins at the surface of lactic acid bacteria: strategies and applications by Michon, C, Langella, P, Eijsink, V G H, Mathiesen, G, Chatel, J M

“…Lactic acid bacteria (LAB) are promising vectors of choice to deliver active molecules to mucosal tissues. They are recognized as safe by the World Health…”
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Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease by Quévrain, E, Maubert, M A, Michon, C, Chain, F, Marquant, R, Tailhades, J, Miquel, S, Carlier, L, Bermúdez-Humarán, L G, Pigneur, B, Lequin, O, Kharrat, P, Thomas, G, Rainteau, D, Aubry, C, Breyner, N, Afonso, C, Lavielle, S, Grill, J-P, Chassaing, G, Chatel, J M, Trugnan, G, Xavier, R, Langella, P, Sokol, H, Seksik, P

“…Crohn's disease (CD)-associated dysbiosis is characterised by a loss of Faecalibacterium prausnitzii, whose culture supernatant exerts an anti-inflammatory…”
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A Commensal Bifidobacterium longum Strain Prevents Gluten-Related Immunopathology in Mice through Expression of a Serine Protease Inhibitor by McCarville, J L, Dong, J, Caminero, A, Bermudez-Brito, M, Jury, J, Murray, J A, Duboux, S, Steinmann, M, Delley, M, Tangyu, M, Langella, P, Mercenier, A, Bergonzelli, G, Verdu, E F

“…Microbiota-modulating strategies, including probiotic administration, have been tested for the treatment of chronic gastrointestinal diseases despite limited…”
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Lactococcus lactis, an efficient cell factory for recombinant protein production and secretion by Morello, E, Bermúdez-Humarán, L G, Llull, D, Solé, V, Miraglio, N, Langella, P, Poquet, I

“…The use of Gram-positive bacteria for heterologous protein production proves to be a useful choice due to easy protein secretion and purification. The lactic…”
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Over-production of exopolysaccharide by Lacticaseibacillus rhamnosus CNCM I-3690 strain cutbacks its beneficial effect on the host by Martín, R., Benítez-Cabello, A., Kulakauskas, S., Viana, M. V. C., Chamignon, C., Courtin, P., Carbonne, C., Chain, F., Pham, H. P., Derrien, Muriel, Bermúdez-Humarán, L. G., Chapot-Chartier, M. P., Smokvina, T., Langella, P.

“…Most lactobacilli produce extracellular polysaccharides that are considered to contribute to the probiotic effect of many strains. Lacticaseibacillus rhamnosus…”
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Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery by Barone, M, Ramayo-Caldas, Y, Estellé, J, Tambosco, K, Chadi, S, Maillard, F, Gallopin, M, Planchais, J, Chain, F, Kropp, C, Rios-Covian, D, Sokol, H, Brigidi, P, Langella, P, Martín, R

“…Most interactions between the host and its microbiota occur at the gut barrier, and primary colonizers are essential in the gut barrier maturation in the early…”
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Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models by Miquel, S., Martín, R., Lashermes, A., Gillet, M., Meleine, M., Gelot, A., Eschalier, A., Ardid, D., Bermúdez-Humarán, L. G., Sokol, H., Thomas, M., Theodorou, V., Langella, P., Carvalho, F. A.

“…Visceral pain and intestinal dysbiosis are associated with Irritable Bowel Syndrome (IBS), a common functional gastrointestinal disorder without available…”
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Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime by Leyrolle, Q, Decoeur, F, Briere, G, Amadieu, C, Quadros, A R A A, Voytyuk, I, Lacabanne, C, Benmamar-Badel, A, Bourel, J, Aubert, A, Sere, A, Chain, F, Schwendimann, L, Matrot, B, Bourgeois, T, Grégoire, S, Leblanc, J G, De Moreno De Leblanc, A, Langella, P, Fernandes, G R, Bretillon, L, Joffre, C, Uricaru, R, Thebault, P, Gressens, P, Chatel, J M, Layé, S, Nadjar, A

“…Maternal immune activation (MIA) and poor maternal nutritional habits are risk factors for the occurrence of neurodevelopmental disorders (NDD). Human studies…”
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Dissecting the respective roles of microbiota and host genetics in the susceptibility of Card9 -/- mice to colitis by Danne, C, Lamas, B, Lavelle, A, Michel, M-L, Da Costa, G, Pham, Hang-Phuong, Lefevre, A, Bridonneau, C, Bredon, M, Planchais, J, Straube, M, Emond, P, Langella, P, Sokol, H

“…The etiology of inflammatory bowel disease (IBD) is unclear but involves both genetics and environmental factors, including the gut microbiota. Indeed,…”
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Correction: Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery by Barone, M, Ramayo-Caldas, Y, Estellé, J, Tambosco, K, Chadi, S, Maillard, F, Gallopin, M, Planchais, J, Chain, F, Kropp, C, Rios-Covian, D, Sokol, H, Brigidi, P, Langella, P, Martín, R

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Immunotherapy of allergic diseases using probiotics or recombinant probiotics by Azevedo, M.S.P., Innocentin, S., Dorella, F.A., Rocha, C.S., Mariat, D., Pontes, D.S., Miyoshi, A., Azevedo, V., Langella, P., Chatel, J.‐M.

“…Summary Allergic diseases affect up to 30% of the western population, and their prevalence is increasing. Probiotics are able to modulate the mucosal immune…”
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Assessment of the safety of Levilactobacillus brevis CNCM I-5321, a probiotic candidate strain isolated from pulque with anti-proliferative activities by Torres-Maravilla, E, Boucard, A-S, Al Azzaz, J, Gontier, S, Kulakauskas, S, Langella, P, Bermúdez-Humarán, L G

“…Gut dysbiosis has been strongly correlated with colorectal cancer (CRC) development and the use of probiotics to modulate this imbalance represents a potential…”
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Gut microbiome and anticancer immune response: really hot Sht by Viaud, S, Daillère, R, Boneca, I G, Lepage, P, Langella, P, Chamaillard, M, Pittet, M J, Ghiringhelli, F, Trinchieri, G, Goldszmid, R, Zitvogel, L

“…The impact of gut microbiota in eliciting innate and adaptive immune responses beneficial for the host in the context of effective therapies against cancer has…”
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Opposing effect of Lactobacillus on in vitro Klebsiella pneumoniae in biofilm and in an in vivo intestinal colonisation model by Lagrafeuille, R, Miquel, S, Balestrino, D, Vareille-Delarbre, M, Chain, F, Langella, P, Forestier, C

“…Beneficial bacteria represent potential sources of therapy, particularly in the battle against antibiotic-resistant pathogens. The Gram-negative bacillus…”
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In vivo transfer of plasmid from food-grade transiting lactococci to murine epithelial cells by Chatel, J-M, Pothelune, L, Ah-Leung, S, Corthier, G, Wal, J-M, Langella, P

“…We recently demonstrated that noninvasive food-grade Lactococcus lactis (L. lactis) can deliver eukaryotic expression plasmid in mammalian cells in vitro …”
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Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis by Dessein, R, Gironella, M, Vignal, C, Peyrin-Biroulet, L, Sokol, H, Secher, T, Lacas-Gervais, S, Gratadoux, J-J, Lafont, F, Dagorn, J-C, Ryffel, B, Akira, S, Langella, P, Nùñez, G, Sirard, J-C, Iovanna, J, Simonet, M, Chamaillard, M

“…Yersinia pseudotuberculosis causes ileitis and mesenteric lymphadenitis by mainly invading the Peyer's patches that are positioned in the terminal ileum…”
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Signal Peptide and Propeptide Optimization for Heterologous Protein Secretion in Lactococcus lactis by LE LOIR, Y, NOUAILLE, S, COMMISSAIRE, J, BRETIGNY, L, GRUSS, A, LANGELLA, P

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Gut ecosystem: how microbes help us by Martín, R, Miquel, S, Ulmer, J, Langella, P, Bermúdez-Humarán, L G

“…The human gut houses one of the most complex and abundant ecosystems composed of up to 1013-1014 microorganisms. Although the anthropocentric concept of life…”
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An intranasal administration of Lactococcus lactis strains expressing recombinant interleukin-10 modulates acute allergic airway inflammation in a murine model by Marinho, F. A. V., Pacífico, L. G. G., Miyoshi, A., Azevedo, V., Le Loir, Y., Guimarães, V. D., Langella, P., Cassali, G. D., Fonseca, C. T., Oliveira, S. C.

“…Summary Background Around 300 million people world‐wide suffer from asthma, and the prevalence of allergic diseases has increased. Much effort has been used in…”
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