Search Results - "Lange, Yvonne"

Transverse distribution of plasma membrane bilayer cholesterol: Picking sides by Steck, Theodore L., Lange, Yvonne

“…The transverse asymmetry (sidedness) of phospholipids in plasma membrane bilayers is well characterized, distinctive, actively maintained and functionally…”
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Is reverse cholesterol transport regulated by active cholesterol? by Steck, Theodore L., Lange, Yvonne

“…This review considers the hypothesis that a small portion of plasma membrane cholesterol regulates reverse cholesterol transport in coordination with overall…”
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Active cholesterol 20 years on by Lange, Yvonne, Steck, Theodore L.

“…This review considers the following hypotheses, some well‐supported and some speculative. Almost all of the sterol molecules in plasma membranes are associated…”
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A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding by Lange, Yvonne, Tabei, S.M. Ali, Steck, Theodore L.

“…Almost all the cholesterol in cellular membranes is associated with phospholipids in simple stoichiometric complexes. This limits the binding of sterol ligands…”
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Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol by Lange, Yvonne, Steck, Theodore L.

“…We review evidence that sterols can form stoichiometric complexes with certain bilayer phospholipids, and sphingomyelin in particular. These complexes appear…”
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Stability and Stoichiometry of Bilayer Phospholipid–Cholesterol Complexes: Relationship to Cellular Sterol Distribution and Homeostasis by Lange, Yvonne, Tabei, S. M. Ali, Ye, Jin, Steck, Theodore L

“…Is cholesterol distributed among intracellular compartments by passive equilibration down its chemical gradient? If so, its distribution should reflect the…”
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Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells by Lange, Yvonne, Ye, Jin, Steck, Theodore L

“…A variety of intercalating amphipaths increase the chemical activity of plasma membrane cholesterol. To test whether intracellular cholesterol can be similarly…”
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How Cholesterol Homeostasis Is Regulated by Plasma Membrane Cholesterol in Excess of Phospholipids by Lange, Yvonne, Ye, Jin, Steck, Theodore L., McConnell, Harden M.

“…How do cells sense and control their cholesterol levels? Whereas most of the cell cholesterol is located in the plasma membrane, the effectors of its abundance…”
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Effectors of Rapid Homeostatic Responses of Endoplasmic Reticulum Cholesterol and 3-Hydroxy-3-methylglutaryl-CoA Reductase by Lange, Yvonne, Ory, Daniel S., Ye, Jin, Lanier, Michael H., Hsu, Fong-Fu, Steck, Theodore L.

“…The cholesterol content of the endoplasmic reticulum (ER) and the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) imbedded therein respond…”
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Essentially all excess fibroblast cholesterol moves from plasma membranes to intracellular compartments by Lange, Yvonne, Ye, Jin, Steck, Theodore L

“…It has been shown that modestly increasing plasma membrane cholesterol beyond its physiological set point greatly increases the endoplasmic reticulum and…”
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Activation of Membrane Cholesterol by 63 Amphipaths by Lange, Yvonne, Ye, Jin, Duban, Mark-Eugene, Steck, Theodore L

“…A few membrane-intercalating amphipaths have been observed to stimulate the interaction of cholesterol with cholesterol oxidase, saponin and cyclodextrin,…”
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Activation of Membrane Cholesterol by Displacement from Phospholipids by Lange, Yvonne, Ye, Jin, Steck, Theodore L.

“…We tested the hypothesis that certain membrane-intercalating agents increase the chemical activity of cholesterol by displacing it from its low activity…”
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Regulation of fibroblast mitochondrial 27-hydroxycholesterol production by active plasma membrane cholesterol by Lange, Yvonne, Steck, Theodore L., Ye, Jin, Lanier, Michael H., Molugu, Vasumathi, Ory, Daniel

“…Side chain oxysterols are cholesterol derivatives thought to signal the abundance of cell cholesterol to homeostatic effector proteins. Here, we investigated…”
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Cholesterol Movement in Niemann-Pick Type C Cells and in Cells Treated with Amphiphiles by Lange, Yvonne, Ye, Jin, Rigney, Mike, Steck, Theodore

“…Cholesterol accumulates to massive levels in cells from Niemann-Pick type C (NP-C) patients and in cells treated with class 2 amphiphiles that mimic NP-C…”
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Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol by Lange, Y, Ye, J, Rigney, M, Steck, T L

“…The abundance of cell cholesterol is governed by multiple regulatory proteins in the endoplasmic reticulum (ER) which, in turn, are under the control of the…”
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Salmonella enterica Serovar Typhimurium Requires Nonsterol Precursors of the Cholesterol Biosynthetic Pathway for Intracellular Proliferation by CATRON, Drew M, LANGE, Yvonne, BORENSZTAJN, Jayme, SYLVESTER, Matthew D, JONES, Bradley D, HALDAR, Kasturi

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Circulation of Cholesterol between Lysosomes and the Plasma Membrane by Lange, Y, Ye, J, Steck, T L

“…The cholesterol in the lysosomes of cultured human fibroblasts was determined to constitute ∼6% of the cell total. This pool was enlarged by as much as…”
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Quantitation of the Pool of Cholesterol Associated with Acyl-CoA:Cholesterol Acyltransferase in Human Fibroblasts by Lange, Yvonne, Steck, Theodore L.

“…The esterification of cholesterol in homogenates of human fibroblasts was explored as a means of estimating the size of the pool of cholesterol associated with…”
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Active cholesterol 20years on by Lange, Yvonne, Steck, Theodore L

“…This review considers the following hypotheses, some well‐supported and some speculative. Almost all of the sterol molecules in plasma membranes are associated…”
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Dynamics of lysosomal cholesterol in Niemann-Pick type C and normal human fibroblasts by Lange, Yvonne, Ye, Jin, Rigney, Mike, Steck, Theodore L

“…The dynamics of endolysosomal cholesterol were investigated in Niemann-Pick type C (NPC) cells and in human fibroblasts treated with class 2 amphiphiles to…”
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