Search Results - "Lange, Tim"

Identification of miR-16 as an endogenous reference gene for the normalization of urinary exosomal miRNA expression data from CKD patients by Lange, Tim, Stracke, Sylvia, Rettig, Rainer, Lendeckel, Uwe, Kuhn, Jana, Schlüter, Rabea, Rippe, Volkhard, Endlich, Karlhans, Endlich, Nicole

“…Chronic kidney disease (CKD) is a severe disorder with an increasing incidence worldwide. An early detection may help to prevent its progression and to…”
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Myeloid-derived suppressor cells in influenza virus-induced asthma exacerbation by van Geffen, Chiel, Lange, Tim, Kolahian, Saeed

“…Myeloid-derived suppressor cells (MDSCs) are a phenotypically heterogenous group of cells that potently suppress the immune response. A growing body of…”
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Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models by Siegerist, Florian, Lange, Tim, Iervolino, Anna, Koppe, Thor Magnus, Zhou, Weibin, Capasso, Giovambattista, Endlich, Karlhans, Endlich, Nicole

“…The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot process architecture, which…”
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Generation of a human induced pluripotent stem cell line (UMGACBi001-A) from urine cells of a chronic kidney disease patient with hypertension, diabetic nephropathy and acute sepsis by Lange, Tim, Bach, Sophia-Marie, Koppe, Thor-Magnus, Klann, Anja, Weise, Anja, Alexander Pilz, Robin, Loth, Norina, Rheinbaben, Sabrina von, Stracke, Sylvia, Endlich, Nicole

“…Chronic kidney disease is a major public health burden associated with a drastically reduced quality of living and life span that lacks suitable,…”
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The ShGlomAssay Combines High-Throughput Drug Screening With Downstream Analyses and Reveals the Protective Role of Vitamin D3 and Calcipotriol on Podocytes by Ristov, Marie-Christin, Lange, Tim, Artelt, Nadine, Nath, Neetika, Kuss, Andreas W., Gehrig, Jochen, Lindenmeyer, Maja, Cohen, Clemens D., Gul, Sheraz, Endlich, Karlhans, Völker, Uwe, Endlich, Nicole

“…Chronic kidney disease (CKD) is a major public health burden affecting more than 500 million people worldwide. Podocytopathies are the main cause for the…”
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Total Asymmetric Synthesis of the Putative Structure of the Cytotoxic Diterpenoid (−)-Sclerophytin A and of the Authentic Natural Sclerophytins A and B by Bernardelli, Patrick, Moradei, Oscar M, Friedrich, Dirk, Yang, Jiong, Gallou, Fabrice, Dyck, Brian P, Doskotch, Raymond W, Lange, Tim, Paquette, Leo A

“…An enantioselective synthetic route to the thermodynamically most stable diastereomer of the structure assigned to sclerophytin A (5) has been realized. The…”
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3633 DIRECT EXOSOME TRANSFECTION WITH FLUORESCENTLY LABELED SMALL RNAS IS A USEFUL TOOL FOR EXOSOMAL CARGO TRAFFICKING AND RNAI IN CULTURED PODOCYTES by Lange, Tim, Schüter, Rabea, Endlich, Nicole

“…Abstract Background and Aims Podocytes, highly-specialized renal epithelial cells, display the outer aspect of the glomerular filtration barrier. Changes of…”
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Recent advances in microwave-assisted combinatorial synthesis and library generation by Lange, Tim, Lindell, Stephen

“…Progress and developments made in microwave-assisted combinatorial synthesis and library production since 2002 are reviewed. The use of microwave technology in…”
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Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling by Paolini, Alessio, Sharipova, Dinara, Lange, Tim, Abdelilah-Seyfried, Salim

“…ABSTRACT During zebrafish heart formation, cardiac progenitor cells converge at the embryonic midline where they form the cardiac cone. Subsequently, this…”
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Correction: Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling by Paolini, Alessio, Sharipova, Dinara, Lange, Tim, Abdelilah-Seyfried, Salim

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BMP4 regulates asymmetric Pkd2 distribution in mouse nodal immotile cilia and ciliary mechanosensing required for left-right determination by Katoh, Takanobu A, Lange, Tim, Nakajima, Yoshiro, Yashiro, Kenta, Okada, Yasushi, Hamada, Hiroshi

“…Mouse nodal immotile cilia mechanically sense the bending direction for left-right (L-R) determination and activate the left-side-specific signaling cascade,…”
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Usability and usefulness of (electronic) patient identification systems—A cross-sectional evaluation in German-speaking radiation oncology departments by Baehr, Andrea, Grohmann, Maximilian, Guberina, Maja, Schulze, Katrin, Lange, Tim, Nestle, Ursula, Ernst, Philipp

“…Purpose Patient misidentification in radiation oncology (RO) is a significant concern due to the potential harm to patient health and the burden on healthcare…”
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The impact of IL‐10 and IL‐17 on myeloid‐derived suppressor cells in vitro and in vivo in a murine model of asthma by Vetter, Charlotte, Schieb, Jakob, Vedder, Nora, Lange, Tim, Brunn, Tobias, Geffen, Chiel, Gercke, Philipp, Kolahian, Saeed

“…Myeloid‐derived suppressor cells (MDSCs) hold promise for clinical applications due to their immunosuppressive properties, particularly in the context of…”
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A Novel High-Content Screening Assay Identified Belinostat as Protective in a FSGS-Like Zebrafish Model by Schindler, Maximilian, Siegerist, Florian, Lange, Tim, Simm, Stefan, Bach, Sophia-Marie, Klawitter, Marianne, Gehrig, Jochen, Gul, Sheraz, Endlich, Nicole

“…FSGS affects the complex three-dimensional morphology of podocytes, resulting in loss of filtration barrier function and the development of sclerotic lesions…”
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FC076: Development of a High-Throughput in Vivo Drug Screening Assay Using a FSGS-Like Zebrafish Model by Schindler, Maximilian, Siegerist, Florian, Lange, Tim, Bach, Sophia-Marie, Klawitter, Marianne, Gehrig, Jochen, Ellinger, Bernhard, Gul, Sheraz, Endlich, Nicole

“…Abstract BACKGROUND AND AIMS Focal segmental sclerosis (FSGS) is a severe histopathological condition which often results in end-stage renal disease. Loss of…”
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MiR‐21 is up‐regulated in urinary exosomes of chronic kidney disease patients and after glomerular injury by Lange, Tim, Artelt, Nadine, Kindt, Frances, Stracke, Sylvia, Rettig, Rainer, Lendeckel, Uwe, Chadjichristos, Christos E., Kavvadas, Panagiotis, Chatziantoniou, Christos, Endlich, Karlhans, Endlich, Nicole

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Design Knowledge for Virtual Learning Companions from a Value-centered Perspective by Schlimbach, Ricarda, Khosrawi-Rad, Bijan, Lange, Tim C., Strohmann, Timo, Robra-Bissantz, Susanne

“…The increasing popularity of conversational agents such as ChatGPT has sparked interest in their potential use in educational contexts but undermines the role…”
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P0053A METHOD FOR THE ISOLATION OF FLUORESCENT GLOMERULI FROM ZEBRAFISH LARVAE by Iervolino, Anna, Lange, Tim, Siegerist, Florian, Schindler, Maximilian, Capasso, Giovambattista, Endlich, Karlhans, Endlich, Nicole

“…Abstract Background and Aims The zebrafish is a powerful animal model to study the glomerular morphology and the function of the permselectivity of the…”
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An Educational Business Model Ideation Tool – Insights from a Design Science Project by Schlimbach, Ricarda, Lange, Tim C., Wagner, Felix, Robra-Bissantz, Susanne, Schoormann, Thorsten

“…Nowadays, it is crucial to teach business model ideation skills in education beyond disciplinary boundaries to shape students’ abilities to innovate processes,…”
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MO030IDENTIFICATION OF REGULATED MRNAS AND MIRNAS IN GLOMERULI ISOLATED FROM AN FSGS-LIKE ZEBRAFISH MODEL by Iervolino, Anna, Lange, Tim, Siccardi, Sabrina, Siegerist, Florian, Caruso, Francesca Pia, Ceccarelli, Michele, Endlich, Karlhans, Capasso, Giovambattista, Endlich, Nicole

“…Abstract Background and Aims The zebrafish (Danio rerio) is a powerful animal model to study glomerular morphology and the function of the permselectivity of…”
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