Search Results - "Lange, Kerstin"
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Barriers and Strategies in Guideline Implementation-A Scoping Review
Published in Healthcare (Basel) (29-06-2016)“…Research indicates that clinical guidelines are often not applied. The success of their implementation depends on the consideration of a variety of barriers…”
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Surface acoustic wave biosensors: a review
Published in Analytical and bioanalytical chemistry (01-07-2008)“…This review presents an overview of 20 years of worldwide development in the field of biosensors based on special types of surface acoustic wave (SAW) devices…”
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Revisiting lab-on-a-chip technology for drug discovery
Published in Nature reviews. Drug discovery (01-08-2012)“…Key Points Recent progress in lab-on-a-chip (LOC) technology and microfluidics is reviewed in this article, with a special focus on drug discovery. We…”
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From dithiocarbamates to branched dithiocarbazates: Compounds with potent antischistosomal activity
Published in Archiv der Pharmazie (Weinheim) (01-03-2023)“…Schistosomiasis or bilharzia is caused by blood flukes of the genus Schistosoma and represents a considerable health and economic burden in tropical and…”
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Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol
Published in Antiviral research (01-03-2020)“…Rocaglates, a class of natural compounds isolated from plants of the genus Aglaia, are potent inhibitors of translation initiation. They are proposed to form…”
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Microfluidic Impedance Biosensor Chips Using Sensing Layers Based on DNA-Based Self-Assembled Monolayers for Label-Free Detection of Proteins
Published in Biosensors (Basel) (13-03-2021)“…A microfluidic chip for electrochemical impedance spectroscopy (EIS) is presented as bio-sensor for label-free detection of proteins by using the example of…”
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Biosensors with label-free detection designed for diagnostic applications
Published in Analytical and bioanalytical chemistry (01-11-2010)“…Since the first biosensor was introduced in 1962 by Clark and Lyons, there has been increasing demand for such analytical devices in diagnostic applications…”
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Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti‐schistosomal Activity
Published in ChemMedChem (06-11-2019)“…The parasitic disease schistosomiasis is the cause of more than 200 000 human deaths per year. Although the disease is treatable, there is one major…”
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Acoustic Biosensors Coated With Phosphorylcholine Groups for Label-Free Detection of Human C-Reactive Protein in Serum
Published in IEEE sensors journal (01-08-2015)“…Mass-sensitive biosensor devices based on surface acoustic waves (SAWs) were coated with commercially available 2-methacryloyloxyethyl phosphorylcholine (MPC)…”
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10
Transformation and acceleration of the construction supply chain through smart factories
Published in Acta Polytechnica CTU proceedings (21-12-2022)“…The European building stock is in high need of refurbishment due to its contribution to excessive global energy consumption. In the North-Sea Region (NSR)…”
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Biarylalkyl Carboxylic Acid Derivatives as Novel Antischistosomal Agents
Published in ChemMedChem (05-07-2016)“…Parasitic platyhelminths are responsible for serious infectious diseases, such as schistosomiasis, which affect humans as well as animals across vast regions…”
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Analysis of transcriptional regulation of the human miR-17-92 cluster; evidence for involvement of Pim-1
Published in International journal of molecular sciences (07-06-2013)“…The human polycistronic miRNA cluster miR-17-92 is frequently overexpressed in hematopoietic malignancies and cancers. Its transcription is in part controlled…”
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Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses
Published in Antiviral research (01-02-2018)“…Coronaviruses (CoV) and picornaviruses are plus-strand RNA viruses that use 5′ cap-dependent and cap-independent strategies, respectively, for viral mRNA…”
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Bulk and Surface Acoustic Wave Biosensors for Milk Analysis
Published in Biosensors (Basel) (05-08-2022)“…Milk and dairy products are common foods and, therefore, are subject to regular controls. Such controls cover both the identification and quantification of…”
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PEI-complexed LNA antiseeds as miRNA inhibitors
Published in RNA biology (01-08-2012)“…Antisense inhibition of oncogenic or other disease-related miRNAs and miRNA families in vivo may provide novel therapeutic strategies. However, this approach…”
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Design and integration of a generic disposable array-compatible sensor housing into an integrated disposable indirect microfluidic flow injection analysis system
Published in Biomedical microdevices (01-10-2011)“…We describe an integration strategy for arbitrary sensors intended to be used as biosensors in biomedical or bioanalytical applications. For such devices ease…”
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Enrichment and identification of Δ9-Tetrahydrocannabinolic acid synthase from Pichia pastoris culture supernatants
Published in Data in brief (01-09-2015)“…This data article refers to the report Δ9-Tetrahydrocannabinolic acid synthase (THCAS) production in Pichia pastoris enables chemical synthesis of cannabinoids…”
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The natural compound silvestrol is a potent inhibitor of Ebola virus replication
Published in Antiviral research (01-01-2017)“…The DEAD-box RNA helicase eIF4A, which is part of the heterotrimeric translation initiation complex in eukaryotes, is an important novel drug target in cancer…”
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Biophotonic sensors with integrated Si3N4-organic hybrid (SiNOH) lasers for point-of-care diagnostics
Published in Light, science & applications (26-03-2021)“…Early and efficient disease diagnosis with low-cost point-of-care devices is gaining importance for personalized medicine and public health protection. Within…”
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A Surface Acoustic Wave Biosensor Concept with Low Flow Cell Volumes for Label-Free Detection
Published in Analytical chemistry (Washington) (15-10-2003)“…Special surface acoustic wave (SAW) devices using horizontally polarized surface shear waves can be operated in water. They allow an easy detection of…”
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