Search Results - "Lange, Beverly"

Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial by Freyer, David R, Prof, Chen, Lu, PhD, Krailo, Mark D, Prof, Knight, Kristin, MS, Villaluna, Doojduen, MS, Bliss, Bonnie, MA, Pollock, Brad H, Prof, Ramdas, Jagadeesh, MD, Lange, Beverly, Prof, Van Hoff, David, BSN, VanSoelen, Michele L, MSN, Wiernikowski, John, PharmD, Neuwelt, Edward A, Prof, Sung, Lillian, Prof

“…Summary Background Sodium thiosulfate is an antioxidant shown in preclinical studies in animals to prevent cisplatin-induced hearing loss with timed…”
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NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report by Ostronoff, Fabiana, Othus, Megan, Gerbing, Robert B., Loken, Michael R., Raimondi, Susana C., Hirsch, Betsy A., Lange, Beverly J., Petersdorf, Stephen, Radich, Jerald, Appelbaum, Frederick R., Gamis, Alan S., Alonzo, Todd A., Meshinchi, Soheil

“…NUP98/NSD1 has recently been reported in association with poor outcome in acute myeloid leukemia (AML). Previous studies also observed a high overlap between…”
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Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors by Castellino, Sharon M, Ullrich, Nicole J, Whelen, Megan J, Lange, Beverly J

“…Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction, commonly months to years after treatment for pediatric brain tumors,…”
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Microbiologically documented infections and infection-related mortality in children with acute myeloid leukemia by Sung, Lillian, Lange, Beverly J., Gerbing, Robert B., Alonzo, Todd A., Feusner, James

“…The primary objective was to describe the prevalence and characteristics of microbiologically defined infections and infection-related mortality (IRM) in 492…”
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Outcomes in CCG-2961, a Children's Oncology Group Phase 3 Trial for untreated pediatric acute myeloid leukemia: a report from the Children's Oncology Group by Lange, Beverly J., Smith, Franklin O., Feusner, James, Barnard, Dorothy R., Dinndorf, Patricia, Feig, Stephen, Heerema, Nyla A., Arndt, Carola, Arceci, Robert J., Seibel, Nita, Weiman, Margie, Dusenbery, Kathryn, Shannon, Kevin, Luna-Fineman, Sandra, Gerbing, Robert B., Alonzo, Todd A.

“…CCG-2961 incorporated 3 new agents, idarubicin, fludarabine and interleukin-2, into a phase 3 AML trial using intensive-timing remission…”
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Differences in Outcomes of Newly Diagnosed Acute Myeloid Leukemia for Adolescent/Young Adult and Younger Patients: A Report from the Children's Oncology Group by CANNER, Jason, ALONZO, Todd A, HORAN, John, FRANKLIN, Janet, FREYER, David R, GAMIS, Alan, GERBING, Robert B, LANGE, Beverly J, MESHINCHI, Soheil, WOODS, William G, PERENTESIS, John

“…Studies comparing survival of adolescent and young adult (AYA) patients to that of younger patients with newly diagnosed acute myeloid leukemia (AML) have…”
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Obesity and Outcome in Pediatric Acute Lymphoblastic Leukemia by BUTTURINI, Anna M, DOREY, Frederick J, SATHER, Harland, TRIGG, Michael, BLEYER, W. Archie, CARROLL, William L, LANGE, Beverly J, HENRY, David W, GAYNON, Paul S, FU, Cecilia, FRANKLIN, Janet, SIEGEL, Stuart E, SEIBEL, Nita L, ROGERS, Paul C

“…To evaluate the effect of obesity (defined as a body mass index > 95th percentile for age and sex at diagnosis) on outcome of pediatric acute lymphoblastic…”
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Clinical implications of FLT3 mutations in pediatric AML by Meshinchi, Soheil, Alonzo, Todd A., Stirewalt, Derek L., Zwaan, Michel, Zimmerman, Martin, Reinhardt, Dirk, Kaspers, Gertjan J.L., Heerema, Nyla A., Gerbing, Robert, Lange, Beverly J., Radich, Jerald P.

“…Activating mutations of the FLT3 gene occur because of an internal tandem duplication of the juxta-membrane domain (FLT3/ITD) or point mutation of the…”
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Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML by Pollard, Jessica A., Alonzo, Todd A., Gerbing, Robert B., Ho, Phoenix A., Zeng, Rong, Ravindranath, Yaddanapudi, Dahl, Gary, Lacayo, Norman J., Becton, David, Chang, Myron, Weinstein, Howard J., Hirsch, Betsy, Raimondi, Susana C., Heerema, Nyla A., Woods, William G., Lange, Beverly J., Hurwitz, Craig, Arceci, Robert J., Radich, Jerald P., Bernstein, Irwin D., Heinrich, Michael C., Meshinchi, Soheil

“…KIT receptor tyrosine kinase mutations are implicated as a prognostic factor in adults with core binding factor (CBF) acute myeloid leukemia (AML). However,…”
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Mortality in Overweight and Underweight Children With Acute Myeloid Leukemia by Lange, Beverly J, Gerbing, Robert B, Feusner, James, Skolnik, Jeffrey, Sacks, Nancy, Smith, Franklin O, Alonzo, Todd A

“…CONTEXT Current treatment for acute myeloid leukemia (AML) in children cures about half the patients. Of the other half, most succumb to leukemia, but 5% to…”
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Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group by Ho, Phoenix A., Alonzo, Todd A., Gerbing, Robert B., Pollard, Jessica, Stirewalt, Derek L., Hurwitz, Craig, Heerema, Nyla A., Hirsch, Betsy, Raimondi, Susana C., Lange, Beverly, Franklin, Janet L., Radich, Jerald P., Meshinchi, Soheil

“…CEBPA mutations have been associated with improved outcome in adult acute myeloid leukemia (AML). We evaluated the prevalence and prognostic significance of…”
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A Pilot Study of Low-Dose Craniospinal Irradiation in Patients With Newly Diagnosed Average-Risk Medulloblastoma by Minturn, Jane E, Mochizuki, Aaron Y, Partap, Sonia, Belasco, Jean B, Lange, Beverly J, Li, Yimei, Phillips, Peter C, Gibbs, Iris C, Fisher, Paul G, Fisher, Michael J, Janss, Anna J

“…Medulloblastoma is one of the most common malignant brain tumors in children. To date, the treatment of average-risk (non-metastatic, completely resected)…”
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Bone-marrow relapse in paediatric acute lymphoblastic leukaemia by Bailey, L Charles, Dr, Lange, Beverly J, Prof, Rheingold, Susan R, MD, Bunin, Nancy J, Prof

“…Summary Marrow relapse is the major obstacle to cure for 10–15% of young patients with acute lymphoblastic leukaemia (ALL). Recent investigations into the…”
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Superior outcome of pediatric acute myeloid leukemia patients with orbital and CNS myeloid sarcoma: A report from the Children's Oncology Group by Johnston, Donna L., Alonzo, Todd A., Gerbing, Robert B., Lange, Beverly J., Woods, William G.

“…Background Extramedullary leukemia (EML) is common in pediatric acute myeloid leukemia (AML) and occurs as leukemia cells within the cerebrospinal fluid (CSF)…”
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Impact of Disease Risk on Efficacy of Matched Related Bone Marrow Transplantation for Pediatric Acute Myeloid Leukemia: The Children's Oncology Group by HORAN, John T, ALONZO, Todd A, LYMAN, Gary H, GERBING, Robert B, LANGE, Beverly J, RAVINDRANATH, Yaddanapudi, BECTON, David, SMITH, Franklin O, WOODS, William G

“…There is considerable variation in the use of HLA-matched related bone marrow transplantation (BMT) for the treatment of pediatric patients with newly…”
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Structural and numerical variation of FLT3/ITD in pediatric AML by Meshinchi, Soheil, Stirewalt, Derek L., Alonzo, Todd A., Boggon, Titus J., Gerbing, Robert B., Rocnik, Jennifer L., Lange, Beverly J., Gilliland, D. Gary, Radich, Jerald P.

“…FLT3 internal tandem duplication (FLT3/ITD) is a common somatic mutation in acute myeloid leukemia (AML) with significant variation in the position, length,…”
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Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia by Buyse, Marc, Squifflet, Pierre, Lange, Beverly J., Alonzo, Todd A., Larson, Richard A., Kolitz, Jonathan E., George, Stephen L., Bloomfield, Clara D., Castaigne, Sylvie, Chevret, Sylvie, Blaise, Didier, Maraninchi, Dominique, Lucchesi, Kathryn J., Burzykowski, Tomasz

“…IL-2 is a natural, T cell–derived cytokine that stimulates the cytotoxic functions of T and natural killer cells. IL-2 monotherapy has been evaluated in…”
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FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report by Redell, Michele S., Ruiz, Marcos J., Gerbing, Robert B., Alonzo, Todd A., Lange, Beverly J., Tweardy, David J., Meshinchi, Soheil

“…Signal transducer and activator of transcription 3 (Stat3) and Stat5 are critical signaling intermediates that promote survival in myeloid leukemias. We…”
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Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group by Ho, Phoenix A., Zeng, Rong, Alonzo, Todd A., Gerbing, Robert B., Miller, Kristen L., Pollard, Jessica A., Stirewalt, Derek L., Heerema, Nyla A., Raimondi, Susana C., Hirsch, Betsy, Franklin, Janet L., Lange, Beverly, Meshinchi, Soheil

“…Recent studies of WT1 mutations in acute myeloid leukemia (AML) mostly report an association with unfavorable clinical outcome. We screened 842 patients…”
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Robert J. Arceci, MD, PhD, 1950-2015 by Woods, William G., Lange, Beverly J.

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