Search Results - "Lang, Yange"
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Therapeutic Potential of a Scorpion Venom-Derived Antimicrobial Peptide and Its Homologs Against Antibiotic-Resistant Gram-Positive Bacteria
Published in Frontiers in microbiology (29-05-2018)“…The alarming rise in the prevalence of antibiotic resistance among pathogenic bacteria poses a unique challenge for the development of effective therapeutic…”
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A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA
Published in Molecular therapy. Nucleic acids (2016)“…Hepatitis B virus (HBV) infection is a major cause of chronic active hepatitis, cirrhosis, and primary hepatocellular carcinoma, all of which are severe…”
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Affinity binding of aptamers to agarose with DNA tetrahedron for removal of hepatitis B virus surface antigen
Published in Colloids and surfaces, B, Biointerfaces (01-06-2019)“…[Display omitted] •Attaching aptamers to agarose through DNA tetrahedral structure to build a novel type of immunosorbent.•This immunosorbent could remove…”
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A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles
Published in The Journal of biological chemistry (04-01-2019)“…Viral infections still threaten human health all over the world, and many people die from viral diseases every year. However, there are no effective vaccines…”
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Systematic identification of four antibacterial peptides from the venom of the scorpion Mesobuthus martensii
Published in Toxicon (Oxford) (01-02-2019)Get full text
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The Kv1.3 ion channel acts as a host factor restricting viral entry
Published in The FASEB journal (01-02-2021)“…Virus entry into cells is the initial stage of infection and involves multiple steps, and interfering viral entry represents potential antiviral approaches…”
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Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1
Published in Theranostics (2018)“…HSV is one of the most widespread human viral pathogens. HSV-1 infects a large portion of the human population and causes severe diseases. The current clinical…”
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A p7 Ion Channel-derived Peptide Inhibits Hepatitis C Virus Infection in Vitro
Published in The Journal of biological chemistry (18-09-2015)“…Viral infection is an early stage of its life cycle and represents a promising target for antiviral drug development. Here we designed and characterized three…”
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Molecular characterisation and expression analysis of defensin genes from the scorpion Mesobuthus martensii
Published in Toxicon (Oxford) (01-02-2019)Get full text
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Molecular basis for the toxin insensitivity of scorpion voltage-gated potassium channel MmKv1
Published in Biochemical journal (01-05-2016)“…Scorpions are insensitive to their own venoms, which contain various neurotoxins specific for mammalian or insect ion channels, whose molecular mechanism…”
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Molecular characterization and expression analysis of CSαβ defensin genes from the scorpion Mesobuthus martensii
Published in Bioscience reports (22-12-2017)“…Defensins are important components of innate host defence system against bacteria, fungi, parasites and viruses. Here, we predicted six potential defensin…”
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