Search Results - "Lang, XiaoE"
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The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study
Published in Translational psychiatry (04-02-2021)“…The associated factors of suicide attempts in patients with major depressive disorder (MDD) comorbid with anxiety remains unclear. To the best of our…”
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The prevalence and clinical correlates of metabolic syndrome and cardiometabolic alterations in 430 drug-naive patients in their first episode of schizophrenia
Published in Psychopharmacology (01-12-2021)“…Rationale Although metabolic abnormalities and metabolic syndrome (MetS) have been extensively investigated in schizophrenia, few studies have examined them in…”
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Effects of low-dose combined olanzapine and sertraline on negative and depressive symptoms in treatment-resistant outpatients with acute exacerbated schizophrenia
Published in Frontiers in pharmacology (21-04-2023)“…Treatment-resistant schizophrenia (TRS) is a major clinical challenge. Current antipsychotic medications do not adequately address negative and depressive…”
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Gender differences in risk factors for suicide attempts among young, first-episode and drug-naive major depressive disorder patients with anxiety symptoms
Published in Frontiers in psychiatry (08-08-2024)“…Suicide attempts and anxiety are common commodities in patients with major depressive disorder (MDD), and suicide attempts are often associated with anxiety…”
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5
Glucose Metabolism and Sex Hormones in Male Patients with Medication-naïve First-episode Schizophrenia: A Large-scale Cross-sectional Study
Published in Current neuropharmacology (01-01-2024)“…Background: Schizophrenia (SCZ) usually begins in early adult life. The underlying molecular mechanisms of SCZ remain unclear. There is evidence for the…”
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Efficacy of low-dose risperidone in combination with sertraline in first-episode drug-naïve patients with schizophrenia: a randomized controlled open-label study
Published in Journal of translational medicine (04-07-2023)“…Despite advances in pharmacology, the treatment of schizophrenia (SZ) remains a challenge due to relapse after antipsychotic discontinuation and multiple…”
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Prevalence and clinical correlates of abnormal lipid metabolism in first-episode and drug-naïve patients with major depressive disorder with abnormal glucose metabolism
Published in Scientific reports (18-05-2023)“…Comorbid glucose metabolism abnormalities are very common in patients with major depressive disorder (MDD), and glucose metabolism and lipid metabolism are…”
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Clinical symptoms, thyroid dysfunction, and metabolic disturbances in first-episode drug-naïve major depressive disorder patients with suicide attempts: A network perspective
Published in Frontiers in endocrinology (Lausanne) (24-02-2023)“…Co-occurrence of thyroid dysfunction, metabolic disturbances, and worsening clinical symptoms in major depressive disorder (MDD) patients with suicidal…”
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Sex difference in the interrelationship between TNF-α and oxidative stress status in first-episode drug-naïve schizophrenia
Published in Journal of neuroinflammation (15-09-2021)“…Increasing evidence indicates that dysregulated TNF-α and oxidative stress (OxS) contribute to the pathophysiology of schizophrenia. Additionally, previous…”
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10
Association of thyroid function with abnormal lipid metabolism in young patients with first-episode and drug naïve major depressive disorder
Published in Frontiers in psychiatry (14-02-2023)“…Abnormal lipid metabolism in patients with major depressive disorder (MDD) has received increasing attention. The coexistence of MDD and abnormal thyroid…”
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Correction: The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study
Published in Translational psychiatry (16-05-2022)Get full text
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12
Gender differences in prevalence and clinical risk factors of suicide attempts in young adults with first-episode drug-naive major depressive disorder
Published in BJPsych open (05-01-2024)“…Suicide rates in adolescents with major depressive disorder (MDD) change with age and gender. Early adulthood is an important transitional stage between late…”
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Association and interaction between overweight/obesity and suicide attempts in young first-episode and drug-naïve patients with major depressive disorder
Published in Heliyon (01-11-2024)“…This research's objective was to explore the correlation of overweight/obesity and suicide attempts in young patients with major depressive disorder (MDD) and…”
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Prevalence and correlates of dyslipidemia in first-episode and drug-naïve major depressive disorder patients with comorbid abnormal glucose metabolism: Sex differences
Published in Frontiers in psychiatry (30-01-2023)“…Lipid metabolism is associated with glucose metabolism, but whether there are variations between sexes in risk factors and prevalence of abnormal lipid…”
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Sexual dimorphism in the relationship between Forkhead-Box P2 and BMI with cognitive deficits in schizophrenia
Published in Frontiers in aging neuroscience (03-08-2022)“…FOXP2 , cognitive deficits, and schizophrenia are associated with neurodegenerative pathophyisiology. Mounting evidence suggests that body mass index (BMI) and…”
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Comparison of Efficacy and Safety Between Low-Dose Ziprasidone in Combination With Sertraline and Ziprasidone Monotherapy for Treatment-Resistant Patients With Acute Exacerbation Schizophrenia: A Randomized Controlled Trial
Published in Frontiers in pharmacology (26-04-2022)“…Treatment-resistant schizophrenia (TRS) is a prevalent clinical problem with heterogeneous presentations. However, the clinical trial designs for new…”
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Prevalence and clinical correlates of subclinical hypothyroidism in first-episode drug-naive patients with major depressive disorder in a large sample of Chinese
Published in Journal of affective disorders (15-02-2020)“…•Subclinical hypothyroidism (SCH) was assayed in 1718 major depressive disorder (MDD).•Severe SCH patients had significantly lower education and later onset of…”
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Sex differences in metabolic disorder patterns of first-episode drug-naive patients with schizophrenia
Published in Psychoneuroendocrinology (01-02-2021)“…•There was a sex difference in the prevalence of metabolic disturbance patterns of first-episode drug-naive schizophrenia.•There was a sex difference in the…”
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Interaction between TNF-α and oxidative stress status in first-episode drug-naïve schizophrenia
Published in Psychoneuroendocrinology (01-04-2020)“…•TNF-α increases in FEDN schizophrenia patients which is positively associated with negative symptoms.•GSH-Px decreases in FEDN schizophrenia patients which is…”
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Prevalence, demographic characteristics, and clinical features of suicide risk in first episode drug-naïve schizophrenia patients with comorbid severe anxiety
Published in Journal of psychiatric research (01-08-2024)“…Both anxiety symptoms and suicide risk are common in schizophrenia. However, previous findings about the association between anxiety and suicide risk in…”
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