Search Results - "Lang, Gerhard K."
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1
Quantity and quality of image artifacts in optical coherence tomography angiography
Published in PloS one (25-01-2019)“…To analyze quality and frequency of OCTA artifacts and to evaluate their impact on the interpretability of OCTA images. 75 patients with diabetic retinopathy…”
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2
Comparison of foveal avascular zone between optical coherence tomography angiography and fluorescein angiography in patients with retinal vein occlusion
Published in PloS one (04-06-2019)“…To compare area of foveal avascular zone (FAZ) in different retinal vascular layers in optical coherence tomography angiography (OCTA) and fluorescein…”
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3
Advanced Non-Destructive Ocular Visualization Methods by Improved X-Ray Imaging Techniques
Published in PloS one (27-01-2017)“…Due to limited X-ray contrast, the use of micro-CT in histology is so far not as widespread as predicted. While specific staining procedures-mostly using…”
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Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure
Published in Journal of diabetes research (2020)“…Inhibitors of dipeptidyl peptidase-4 (DPP-4) are widely used to treat diabetes mellitus, but data concerning their effects on the barrier stability of retinal…”
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Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165
Published in Cellular physiology and biochemistry (2017)“…Abstract Background/Aims: Hallmark of diabetic macular edema is the enhanced permeability of retinal endothelial cells (REC) induced by vascular endothelial…”
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Type of culture medium determines properties of cultivated retinal endothelial cells: induction of substantial phenotypic conversion by standard DMEM
Published in Heliyon (01-01-2021)“…Contradictory behavior of microvascular retinal endothelial cells (REC) - a reliable in vitro model to study retinal diseases - have recently been reported…”
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Transport and fate of aflibercept in VEGF-A165-challenged retinal endothelial cells
Published in Experimental eye research (01-09-2020)“…Retinal vessels are at least in part involved in clearing of Fc terminus-containing proteins from the vitreous. In vitro, the Fc fusion protein aflibercept is…”
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Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells
Published in Experimental eye research (01-05-2014)“…Members of the vascular endothelial growth factor (VEGF) family differently regulate processes in retinal endothelial cells (REC) which are crucially involved…”
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VEGF receptor 2 inhibitor nintedanib completely reverts VEGF-A165-induced disturbances of barriers formed by retinal endothelial cells or long-term cultivated ARPE-19 cells
Published in Experimental eye research (01-05-2020)“…Various severe ocular diseases are associated with an elevated intravitreal expression of VEGF-A which increases the permeability of retinal endothelial cells…”
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10
Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor
Published in Experimental eye research (01-02-2016)“…Bevacizumab is one of the VEGF-binding proteins that are established in clinical practice to treat various ocular diseases. In view of therapeutic long-term…”
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11
Fate of the Fc fusion protein aflibercept in retinal endothelial cells: competition of recycling and degradation
Published in Graefe's archive for clinical and experimental ophthalmology (01-01-2019)“…Purpose Intravitreal injection of the VEGF-binding protein aflibercept is widely used to treat various ocular diseases. In vitro, immortalized bovine retinal…”
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12
VEGF but not PlGF disturbs the barrier of retinal endothelial cells
Published in Experimental eye research (01-10-2013)“…Elevated permeability of retinal endothelial cells (REC), as observed in diabetic retinopathy (DR), is induced by extended exposure to ≥25 ng/ml vascular…”
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13
Accurate OCT-angiography Interpretation - Detection and Exclusion of Artifacts
Published in Klinische Monatsblatter fur Augenheilkunde (01-09-2017)“…Optical coherence tomography angiography (OCTA) provides, non-invasively, a three-dimensional visualization of the microvasculature of the retina and choroid…”
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14
Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells
Published in Experimental eye research (01-01-2017)“…Retinal endothelial cells (REC) likely contribute to the clearance of intravitreally injected IgG. Because this is of high relevance to the pharmacokinetic…”
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15
Effect of growth factors on proliferation and expression of growth factor receptors in a human lens epithelial cell line
Published in Journal of cataract and refractive surgery (01-03-2006)“…To investigate the effect of basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), insulin-like growth factor 1 (IGF-1), and transforming…”
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16
Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A 165
Published in Cellular physiology and biochemistry (01-10-2017)“…Background/Aims: Hallmark of diabetic macular edema is the enhanced permeability of retinal endothelial cells (REC) induced by vascular endothelial growth…”
Get full text
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17
In Vitro Study of Subablative Er : YAG Laser and Diode Laser Therapy vs. Thermal Cautery in Microbial Keratitis
Published in Klinische Monatsblatter fur Augenheilkunde (01-11-2019)“…In microbial keratitis, thermal cautery leads to thermal necrosis associated with germ reduction. Subablative heating of the cornea using an Er : YAG laser or…”
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18
Free-Floating Intraocular Cysts
Published in Klinische Monatsblatter fur Augenheilkunde (01-09-2018)“…Free-floating intraocular cysts may be found in the anterior chamber (FZV) and the vitreous (FZG). The first description of a cyst was 150 years ago, and they…”
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Visualization of Retinal Neovascularization with Optical Coherence Tomography Angiography in Comparison with Fluorescein Angiography
Published in Klinische Monatsblatter fur Augenheilkunde (01-11-2019)“…Comparison of retinal neovascularizations of the disc (NVD) and elsewhere (NVE) in optical coherence tomography angiography (OCTA) and fluorescein angiography…”
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20
The Importance of the Preoperative Information from a Patient's Perspective - a Structured Interview of 100 Ophthalmological University-Based Outpatients
Published in Klinische Monatsblatter fur Augenheilkunde (01-03-2020)“…The patient's knowledge about their illness, as well as their expectations regarding pre-intervention, consultation and treatment, may differ from the…”
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