Search Results - "Lang, F"

The PAR proteins: from molecular circuits to dynamic self-stabilizing cell polarity by Lang, Charles F, Munro, Edwin

“…PAR proteins constitute a highly conserved network of scaffolding proteins, adaptors and enzymes that form and stabilize cortical asymmetries in response to…”
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Fast estimation of the look-elsewhere effect using Gaussian random fields by Qin, Juehang, Lang, Rafael F.

“…We discuss the use of Gaussian random fields to estimate the look-elsewhere effect correction. We show that Gaussian random fields can be used to model the…”
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Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma by Li, X, Liu, Y, Granberg, K J, Wang, Q, Moore, L M, Ji, P, Gumin, J, Sulman, E P, Calin, G A, Haapasalo, H, Nykter, M, Shmulevich, I, Fuller, G N, Lang, F F, Zhang, W

“…MIR-491 is commonly co-deleted with its adjacent CDKN2A on chromosome 9p21.3 in glioblastoma multiforme (GBM). However, it is not known whether deletion of…”
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Psychopathological long-term outcome of schizophrenia - a review by Lang, F. U., Kösters, M., Lang, S., Becker, T., Jäger, M.

“…Objective In the past, the comparability of empirical studies that examined the course and outcome of schizophrenia was limited by their use of different…”
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Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma by Lang, Frederick F, Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W K Alfred, Sawaya, Raymond, Weinberg, Jeffrey S, Prabhu, Sujit S, Rao, Ganesh, Fuller, Gregory N, Aldape, Kenneth D, Gumin, Joy, Vence, Luis M, Wistuba, Ignacio, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Dirven, Clemens M F, Tejada, Sonia, Valle, Ricardo D, Alonso, Marta M, Ewald, Brett, Peterkin, Joanna J, Tufaro, Frank, Fueyo, Juan

“…Purpose DNX-2401 (Delta-24-RGD; tasadenoturev) is a tumor-selective, replication-competent oncolytic adenovirus. Preclinical studies demonstrated antiglioma…”
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Mesenchymal stem cells as natural biofactories for exosomes carrying miR-124a in the treatment of gliomas by Lang, Frederick M, Hossain, Anwar, Gumin, Joy, Momin, Eric N, Shimizu, Yuzaburo, Ledbetter, Dan, Shahar, Tal, Yamashita, Shinji, Parker Kerrigan, Brittany, Fueyo, Juan, Sawaya, Raymond, Lang, Frederick F

“…MicroRNAs (miRs) are promising new therapeutics for glioblastoma. However, which miRs are most effective against glioblastomas and how these miRs should be…”
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Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target by Abdelfattah, Nourhan, Kumar, Parveen, Wang, Caiyi, Leu, Jia-Shiun, Flynn, William F., Gao, Ruli, Baskin, David S., Pichumani, Kumar, Ijare, Omkar B., Wood, Stephanie L., Powell, Suzanne Z., Haviland, David L., Parker Kerrigan, Brittany C., Lang, Frederick F., Prabhu, Sujit S., Huntoon, Kristin M., Jiang, Wen, Kim, Betty Y. S., George, Joshy, Yun, Kyuson

“…A major rate-limiting step in developing more effective immunotherapies for GBM is our inadequate understanding of the cellular complexity and the molecular…”
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Extent of Resection of Glioblastoma Revisited: Personalized Survival Modeling Facilitates More Accurate Survival Prediction and Supports a Maximum-Safe-Resection Approach to Surgery by MARKO, Nicholas F, WEIL, Robert J, SCHROEDER, Jason L, LANG, Frederick F, SUKI, Dima, SAWAYA, Raymond E

“…Approximately 12,000 glioblastomas are diagnosed annually in the United States. The median survival rate for this disease is 12 months, but individual survival…”
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Recommended conventions for reporting results from direct dark matter searches by Baxter, D., Bloch, I. M., Bodnia, E., Chen, X., Conrad, J., Di Gangi, P., Dobson, J. E. Y., Durnford, D., Haselschwardt, S. J., Kaboth, A., Lang, R. F., Lin, Q., Lippincott, W. H., Liu, J., Manalaysay, A., McCabe, C., Morå, K. D., Naim, D., Neilson, R., Olcina, I., Piro, M. -C., Selvi, M., von Krosigk, B., Westerdale, S., Yang, Y., Zhou, N.

“…The field of dark matter detection is a highly visible and highly competitive one. In this paper, we propose recommendations for presenting dark matter direct…”
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Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination by Jiang, Hong, Rivera-Molina, Yisel, Gomez-Manzano, Candelaria, Clise-Dwyer, Karen, Bover, Laura, Vence, Luis M, Yuan, Ying, Lang, Frederick F, Toniatti, Carlo, Hossain, Mohammad B, Fueyo, Juan

“…Oncolytic viruses selectively lyse tumor cells, disrupt immunosuppression within the tumor, and reactivate antitumor immunity, but they have yet to live up to…”
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Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 by Figueroa, Javier, Phillips, Lynette M, Shahar, Tal, Hossain, Anwar, Gumin, Joy, Kim, Hoon, Bean, Andrew J, Calin, George A, Fueyo, Juan, Walters, Edgar T, Kalluri, Raghu, Verhaak, Roel G, Lang, Frederick F

“…Tumor-stromal communications impact tumorigenesis in ways that are incompletely understood. Here, we show that glioma-associated human mesenchymal stem cells…”
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Soil phosphorus supply controls P nutrition strategies of beech forest ecosystems in Central Europe by Lang, F., Krüger, J., Amelung, W., Willbold, S., Frossard, E., Bünemann, E. K., Bauhus, J., Nitschke, R., Kandeler, E., Marhan, S., Schulz, S., Bergkemper, F., Schloter, M., Luster, J., Guggisberg, F., Kaiser, K., Mikutta, R., Guggenberger, G., Polle, A., Pena, R., Prietzel, J., Rodionov, A., Talkner, U., Meesenburg, H., von Wilpert, K., Hölscher, A., Dietrich, H. P., Chmara, I.

“…Phosphorus availability may shape plant–microorganism–soil interactions in forest ecosystems. Our aim was to quantify the interactions between soil P…”
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Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a by Tiwary, Shweta, Morales, John E., Kwiatkowski, Sam C., Lang, Frederick F., Rao, Ganesh, McCarty, Joseph H.

“…Disruption of the blood-brain barrier (BBB) by cancer cells is linked to metastatic tumor initiation and progression; however, the pathways that drive these…”
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Axial QCT: Clinical Applications and New Developments by Link, Thomas M, Lang, Thomas F

“…Abstract Quantitative computed tomography (QCT) is currently undergoing a renaissance, with an increasing number of studies being published and the definition…”
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Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL‐6/gp130/STAT3 Pathway by Hossain, Anwar, Gumin, Joy, Gao, Feng, Figueroa, Javier, Shinojima, Naoki, Takezaki, Tatsuya, Priebe, Waldemar, Villarreal, Diana, Kang, Seok‐Gu, Joyce, Celine, Sulman, Erik, Wang, Qianghu, Marini, Frank C., Andreeff, Michael, Colman, Howard, Lang, Frederick F.

“…Although mesenchymal stem cells (MSCs) have been implicated as stromal components of several cancers, their ultimate contribution to tumorigenesis and their…”
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Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation by Do, Catherine, Lang, Charles F., Lin, John, Darbary, Huferesh, Krupska, Izabela, Gaba, Aulona, Petukhova, Lynn, Vonsattel, Jean-Paul, Gallagher, Mary P., Goland, Robin S., Clynes, Raphael A., Dwork, Andrew, Kral, John G., Monk, Catherine, Christiano, Angela M., Tycko, Benjamin

“…Haplotype-dependent allele-specific methylation (hap-ASM) can impact disease susceptibility, but maps of this phenomenon using stringent criteria in…”
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Ultracold triplet molecules in the rovibrational ground state by Lang, F, Winkler, K, Strauss, C, Grimm, R, Denschlag, J Hecker

“…We report here on the production of an ultracold gas of tightly bound Rb2 triplet molecules in the rovibrational ground state, close to quantum degeneracy…”
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Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas by Alonso, Marta M, Diez-Valle, Ricardo, Manterola, Lorea, Rubio, Angel, Liu, Dan, Cortes-Santiago, Nahir, Urquiza, Leire, Jauregi, Patricia, Lopez de Munain, Adolfo, Sampron, Nicolás, Aramburu, Ander, Tejada-Solís, Sonia, Vicente, Carmen, Odero, María D, Bandrés, Eva, García-Foncillas, Jesús, Idoate, Miguel A, Lang, Frederick F, Fueyo, Juan, Gomez-Manzano, Candelaria

“…We undertook this study to understand how the transcription factor Sox2 contributes to the malignant phenotype of glioblastoma multiforme (GBM), the most…”
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Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients by Figueroa, Javier M, Skog, Johan, Akers, Johnny, Li, Hongying, Komotar, Ricardo, Jensen, Randy, Ringel, Florian, Yang, Isaac, Kalkanis, Steven, Thompson, Reid, LoGuidice, Lori, Berghoff, Emily, Parsa, Andrew, Liau, Linda, Curry, William, Cahill, Daniel, Bettegowda, Chetan, Lang, Frederick F, Chiocca, E Antonio, Henson, John, Kim, Ryan, Breakefield, Xandra, Chen, Clark, Messer, Karen, Hochberg, Fred, Carter, Bob S

“…RNAs within extracellular vesicles (EVs) have potential as diagnostic biomarkers for patients with cancer and are identified in a variety of biofluids…”
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Anisotropic local modification of crystal field levels in Pr-based pyrochlores: a muon-induced effect modeled using density functional theory by Foronda, F R, Lang, F, Möller, J S, Lancaster, T, Boothroyd, A T, Pratt, F L, Giblin, S R, Prabhakaran, D, Blundell, S J

“…Although muon spin relaxation is commonly used to probe local magnetic order, spin freezing, and spin dynamics, we identify an experimental situation in which…”
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