Search Results - "Lang, Emma"
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Assessment of Diagnostic Strategy for Early Recognition of Bullous and Nonbullous Variants of Pemphigoid
Published in JAMA dermatology (Chicago, Ill.) (01-02-2019)“…A substantial number of patients with bullous pemphigoid do not develop skin blisters and may not have received the correct diagnosis. Diagnostic criteria and…”
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Pyruvate decarboxylase and thiamine biosynthetic genes are regulated differently by Pdc2 in S. cerevisiae and C. glabrata
Published in PloS one (07-06-2023)“…Understanding metabolism in the pathogen Candida glabrata is key to identifying new targets for antifungals. The thiamine biosynthetic (THI) pathway is…”
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Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors
Published in PLoS neglected tropical diseases (01-03-2015)“…New mode-of-action insecticides are sought to provide continued control of pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We…”
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A Novel cis Element Achieves the Same Solution as an Ancestral cis Element During Thiamine Starvation in Candida glabrata
Published in G3 : genes - genomes - genetics (01-01-2020)“…Regulatory networks often converge on very similar sequences to drive transcriptional programs due to constraints on what transcription factors are present. To…”
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Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2022)“…Cellular quiescence is a state of reversible cell cycle arrest that is associated with tissue dormancy. Timely regulated entry into and exit from quiescence is…”
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Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Published in Nature communications (10-09-2018)“…Epithelial sheet spreading is a fundamental cellular process that must be coordinated with cell division and differentiation to restore tissue integrity. Here…”
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Endometriosis as a rare cause of small bowel obstruction
Published in ANZ journal of surgery (01-11-2020)Get full text
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Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides
Published in Pesticide biochemistry and physiology (01-07-2013)“…[Display omitted] •The PIDP was established to pursue target-based insecticide discovery.•Screens identified agonists and antagonists of mosquito and tick…”
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Topology-guided polar ordering of collective cell migration
Published in Science advances (19-04-2024)“…The ability of epithelial monolayers to self-organize into a dynamic polarized state, where cells migrate in a uniform direction, is essential for tissue…”
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Influence of acute promyelocytic leukemia therapeutic drugs on nuclear pore complex density and integrity
Published in Biochemical and biophysical research communications (15-05-2018)“…During cell division, a large number of nuclear proteins are released into the cytoplasm due to nuclear envelope breakdown. Timely nuclear import of these…”
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The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling
Published in Blood (26-07-2012)“…Arsenic in the form of arsenic trioxide (ATO) is used as a therapeutic drug for treatment of acute promyelocytic leukemia (APL). The mechanism by which this…”
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PML Bodies in Mitosis
Published in Cells (Basel, Switzerland) (14-08-2019)“…Promyelocytic leukemia (PML) bodies are dynamic intracellular structures that recruit and release a variety of different proteins in response to stress, virus…”
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The Inner Membrane Protein PilG Interacts with DNA and the Secretin PilQ in Transformation
Published in PloS one (06-08-2015)“…Expression of type IV pili (Tfp), filamentous appendages emanating from the bacterial surface, is indispensable for efficient neisserial transformation. Tfp…”
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Lithium neurotoxicity: the development of irreversible neurological impairment despite standard monitoring of serum lithium levels
Published in Journal of clinical neuroscience (01-05-2002)“…We report the case of a 44 year old man who presented with a two-month history of dysarthria, ataxia and leg weakness whilst on maintenance lithium for bipolar…”
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Role of Transcription Factor Pdc2 in the Thiamine Signal Transduction Pathway in Candida glabrata and Saccharomyces cerevisiae
Published in The FASEB journal (01-05-2022)“…Abstract only Pdc2 is critical for the transcriptional response to thiamine starvation in S. cerevisiae and C. glabrata . In this study, we determined how Pdc2…”
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Role of Transcription Factor Pdc2 in the Thiamine Signal Transduction Pathway in Candida glabrataand Saccharomyces cerevisiae
Published in The FASEB journal (01-05-2022)“…Pdc2 is critical for the transcriptional response to thiamine starvation in S. cerevisiae and C. glabrata. In this study, we determined how Pdc2 drives…”
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Promyelocytic leukemia bodies tether to early endosomes during mitosis
Published in Cell cycle (Georgetown, Tex.) (01-06-2014)“…During mitosis the nuclear envelope breaks down, leading to potential interactions between cytoplasmic and nuclear components. PML bodies are nuclear…”
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Meconium ileus and pancreatic sufficiency with D1152H mutation: A case report and review of the literature
Published in Journal of cystic fibrosis (01-11-2023)“…•Meconium ileus may be the first clinical presentation in patients with D1152H.•Sweat testing alone in patients with D1152H is insufficient to suggest against…”
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Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Published in Nucleus (Austin, Tex.) (04-07-2017)“…Selective nuclear import in eukaryotic cells involves sequential interactions between nuclear import receptors and phenylalanine-glycine (FG)-repeat…”
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Identification of neisserial DNA binding components
Published in Microbiology (Society for General Microbiology) (01-03-2009)“…1 Centre for Molecular Biology and Neuroscience, Institute of Microbiology, University of Oslo, N-0027 Oslo, Norway 2 Centre for Molecular Biology and…”
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