Search Results - "Lang, Dirk M."

Lipid Raft- and Protein Kinase C-mediated Synergism between Glucocorticoid- and Gonadotropin-releasing Hormone Signaling Results in Decreased Cell Proliferation by Wehmeyer, Lancelot, Du Toit, Andrea, Lang, Dirk M., Hapgood, Janet P.

“…Cross-talk between the glucocorticoid receptor (GR) and other receptors is emerging as a mechanism for fine-tuning cellular responses. We have previously shown…”
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Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome by Gessner, Sophia, Martin, Zela Alexandria-Mae, Reiche, Michael A, Santos, Joana A, Dinkele, Ryan, Ramudzuli, Atondaho, Dhar, Neeraj, de Wet, Timothy J, Anoosheh, Saber, Lang, Dirk M, Aaron, Jesse, Chew, Teng-Leong, Herrmann, Jennifer, Müller, Rolf, McKinney, John D, Woodgate, Roger, Mizrahi, Valerie, Venclovas, Česlovas, Lamers, Meindert H, Warner, Digby F

“…A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence of drug resistance in during anti-tuberculosis (TB) chemotherapy. However,…”
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Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape by Parihar, Suraj P, Guler, Reto, Lang, Dirk M, Suzuki, Harukazu, Marais, A David, Brombacher, Frank

“…Statins are well-known cholesterol lowering drugs targeting HMG-CoA-reductase, reducing the risk of coronary disorders and hypercholesterolemia. Statins are…”
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Characterisation of innate fungal recognition in the lung by Faro-Trindade, Inês, Willment, Janet A, Kerrigan, Ann M, Redelinghuys, Pierre, Hadebe, Sabelo, Reid, Delyth M, Srinivasan, Naren, Wainwright, Helen, Lang, Dirk M, Steele, Chad, Brown, Gordon D

“…The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface…”
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Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2 by Stuermer, C A, Lang, D M, Kirsch, F, Wiechers, M, Deininger, S O, Plattner, H

“…Using confocal laser scanning and double immunogold electron microscopy, we demonstrate that reggie-1 and -2 are colocalized in < or =0.1-microm plasma…”
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Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation by Parihar, Suraj P., Guler, Reto, Khutlang, Rethabile, Lang, Dirk M., Hurdayal, Ramona, Mhlanga, Musa M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank

“…Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby reducing the risk of coronary disorders and hypercholesterolemia…”
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Intracellular mechanics and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments by Higgins, Ghodeejah, Higgins, Faatiemah, Peres, Jade, Lang, Dirk M., Abdalrahman, Tamer, Zaman, Muhammad H., Prince, Sharon, Franz, Thomas

“…Cell stiffness and T-box transcription factor 3 (TBX3) expression have been identified as biomarkers of melanoma metastasis in 2D environments. This study…”
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Vimentin Modulates Infectious Internalization of Human Papillomavirus 16 Pseudovirions by Schäfer, Georgia, Graham, Lisa M, Lang, Dirk M, Blumenthal, Melissa J, Bergant Marušič, Martina, Katz, Arieh A

“…Human papillomavirus (HPV) infection is the most common viral infection of the reproductive tract, with virtually all cases of cervical cancer being…”
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Cytoskeletal tubulin competes with actin to increase deformability of metastatic melanoma cells by Higgins, Ghodeejah, Peres, Jade, Abdalrahman, Tamer, Zaman, Muhammad H., Lang, Dirk M., Prince, Sharon, Franz, Thomas

“…The formation of membrane protrusions during migration is reliant upon the cells’ cytoskeletal structure and stiffness. It has been reported that actin…”
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Effect of paclitaxel treatment on cellular mechanics and morphology of human oesophageal squamous cell carcinoma in 2D and 3D environments by Kiwanuka, Martin, Higgins, Ghodeejah, Ngcobo, Silindile, Nagawa, Juliet, Lang, Dirk M, Zaman, Muhammad H, Davies, Neil H, Franz, Thomas

“…During chemotherapy, structural and mechanical changes in malignant cells have been observed in several cancers, including leukaemia and pancreatic and…”
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Nogo‐A does not inhibit retinal axon regeneration in the lizard Gallotia galloti by Lang, Dirk M., Romero‐Alemán, Maria del Mar, Dobson, Bryony, Santos, Elena, Monzón‐Mayor, Maximina

“…ABSTRACT The myelin‐associated protein Nogo‐A contributes to the failure of axon regeneration in the mammalian central nervous system (CNS). Inhibition of axon…”
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Evolution of duplicated reggie genes in zebrafish and goldfish by Málaga-Trillo, Edward, Laessing, Ute, Lang, Dirk M, Meyer, Axel, Stuermer, Claudia A O

“…Invertebrates, tetrapod vertebrates, and fish might be expected to differ in their number of gene copies, possibly due the occurrence of genome duplication…”
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A novel assay of antimycobacterial activity and phagocytosis by human neutrophils by Lowe, David M, Bangani, Nonzwakazi, Mehta, Meera R, Lang, Dirk M, Rossi, Adriano G, Wilkinson, Katalin A, Wilkinson, Robert J, Martineau, Adrian R

“…Summary Despite abundant evidence that neutrophils arrive early at sites of mycobacterial disease and phagocytose organisms, techniques to assay phagocytosis…”
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Tenascin‐R and axon growth‐promoting molecules are up‐regulated in the regenerating visual pathway of the lizard (Gallotia galloti) by Lang, Dirk M., Monzon‐Mayor, Maximina, del Mar Romero‐Aleman, Maria, Yanes, Carmen, Santos, Elena, Pesheva, Penka

“…It is currently unclear whether retinal ganglion cell (RGC) axon regeneration depends on down‐regulation of axon growth‐inhibitory proteins, and to what extent…”
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Early coevolution of adhesive but not antiadhesive tenascin-R ligand-receptor pairs in vertebrates: A phylogenetic study by Pesheva, Penka, Probstmeier, Rainer, Lang, Dirk M., McBride, Ruth, Hsu, Nai-Jen, Gennarini, Gianfranco, Spiess, Eberhard, Peshev, Zolo

“…Axon growth inhibitory CNS matrix proteins, such as tenascin-R (TN-R), have been supposed to contribute to the poor regenerative capacity of adult mammalian…”
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Topographic Restriction of TAG-1 Expression in the Developing Retinotectal Pathway and Target Dependent Reexpression during Axon Regeneration by Lang, Dirk M., Warren, James T., Klisa, Christiane, Stuermer, Claudia A.O.

“…TAG-1, a glycosylphosphatidyl inositol (GPI)-anchored protein of the immunoglobulin (Ig) superfamily, exhibits an unusual spatiotemporal expression pattern in…”
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Modulation of the Inhibitory Substrate Properties of Oligodendrocytes by Platelet-Derived Growth Factor by Lang, Dirk M, Hille, Michael G, Schwab, Martin E, Stuermer, Claudia A. O

“…Although growth cones typically collapse after encountering O1/galactocerebroside (GalC)-positive oligodendrocytes, the majority of growth cones traversed…”
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Baseline brain perfusion and brain structure in patients with major depression: a multimodal magnetic resonance imaging study by Vasic, Nenad, MD, Dudek, Manuela, Otte, Stefanie, MD, Grön, Georg, PhD, Sosic-Vasic, Zrinka, PhD, Connemann, Bernhard J., MD, von Strombeck, Anna, PhD, Sambataro, Fabio, MD, PhD, Lang, Dirk, MD, Wolf, Nadine D., MD, Wolf, Robert C

“…Background Abnormal regional cerebral blood flow (rCBF) and grey matter volume have been frequently reported in patients with major depressive disorder (MDD)…”
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Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape: e75490 by Parihar, Suraj P, Guler, Reto, Lang, Dirk M, Suzuki, Harukazu, Marais, A David, Brombacher, Frank

“…Statins are well-known cholesterol lowering drugs targeting HMG-CoA-reductase, reducing the risk of coronary disorders and hypercholesterolemia. Statins are…”
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Regeneration of retinal axons in the lizard Gallotia galloti is not linked to generation of new retinal ganglion cells by Lang, Dirk M., del Mar Romero‐Aleman, Maria, Arbelo‐Galvan, Juan‐Francisco, Stuermer, Claudia A.O., Monzon‐Mayor, Maximina

“…Using anterograde tracing with HRP and antibodies (ABs) against neurofilaments, we show that regrowth of retinal ganglion cell (RGC) axons in the lizard…”
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