Search Results - "Lang, Christian A."

Three-dimensional Analysis and Reconstruction of Additively Manufactured Materials in the Cloud-Based BisQue Infrastructure by Polonsky, Andrew T., Lang, Christian A., Kvilekval, Kristian G., Latypov, Marat I., Echlin, McLean P., Manjunath, B. S., Pollock, Tresa M.

“…A microstructure analytics and 3D reconstruction software package, DREAM.3D, was integrated as a module into a cloud-based platform, BisQue. Parallelization of…”
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Modulating ALS-Related Amyloidogenic TDP-43307–319 Oligomeric Aggregates with Computationally Derived Therapeutic Molecules by Laos, Veronica, Bishop, Dezmond, Lang, Christian A, Marsh, Nicole M, Cantrell, Kristi Lazar, Buratto, Steven K, Singh, Ambuj K, Bowers, Michael T

“…TDP-43 aggregates are a salient feature of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and a variety of other neurodegenerative…”
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Inhibiting and Remodeling Toxic Amyloid-Beta Oligomer Formation Using a Computationally Designed Drug Molecule That Targets Alzheimer’s Disease by Downey, Matthew A., Giammona, Maxwell J., Lang, Christian A., Buratto, Steven K., Singh, Ambuj, Bowers, Michael T.

“…Alzheimer’s disease (AD) is rapidly reaching epidemic status among a burgeoning aging population. Much evidence suggests the toxicity of this amyloid disease…”
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Modulating ALS-Related Amyloidogenic TDP-43 307-319 Oligomeric Aggregates with Computationally Derived Therapeutic Molecules by Laos, Veronica, Bishop, Dezmond, Lang, Christian A, Marsh, Nicole M, Cantrell, Kristi Lazar, Buratto, Steven K, Singh, Ambuj K, Bowers, Michael T

“…TDP-43 aggregates are a salient feature of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and a variety of other neurodegenerative…”
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Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking by Lang, Christian A., Ray, Soumya S., Liu, Min, Singh, Ambuj K., Cuny, Gregory D.

“…[Display omitted] Joint pharmacophore space (JPS), ensemble docking and sequential JPS-ensemble docking were used to select three panels of compounds (10 per…”
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BisQue for 3D Materials Science in the Cloud: Microstructure–Property Linkages by Latypov, Marat I., Khan, Amil, Lang, Christian A., Kvilekval, Kris, Polonsky, Andrew T., Echlin, McLean P., Beyerlein, Irene J., Manjunath, B. S., Pollock, Tresa M.

“…Accelerating the design and development of new advanced materials is one of the priorities in modern materials science. These efforts are critically dependent…”
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WhiteWater: Distributed Processing of Fast Streams by Stanoi, I., Mihaila, G.A., Lang, C.A., Palpanas, T.

“…Monitoring systems today often involve continuous queries over streaming data in a distributed collaborative fashion. The distribution of query operators over…”
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Increasing Buffer-Locality for Multiple Relational Table Scans through Grouping and Throttling by Lang, C.A., Bhattacharjee, B., Malkemus, T., Padmanabhan, S., Kwai Wong

“…Decision support (DSS) workloads generally contain multiple large concurrent scan operations. These are often executed as relational table scans which can take…”
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Poster Session: Improved Buffer Size Adaptation through Cache/Controller Coupling by Lang, Christian A., Bhattacharjee, Bishwaranjan, Malkemus, Tim, Stanoi, Ioana

“…Database workloads seldom remain static. A system tuned by an expert for the current environment, might not always remain optimal. To deal with this situation,…”
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Making the threshold algorithm access cost aware by Lang, C.A., Yuan-Chi Chang, Smith, J.R.

“…Assume a database storing N objects with d numerical attributes or feature values. All objects in the database can be assigned an overall score that is derived…”
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Hint and run: accelerating XPath queries by Stanoi, I., Lang, C.A., Padmanabhan, S.

“…XML documents are often represented as DOM structures or trees. In some instances, due to the complexity of queries, XPath queries are better evaluated by…”
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Joining massive high-dimensional datasets by Kahveci, T., Lang, C.A., Singh, A.K.

“…We consider the problem of joining massive datasets. We propose two techniques for minimizing disk I/O cost of join operations for both spatial and sequence…”
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