Search Results - "Lane, S W"

Protein Composition of Immunoprecipitated Synaptic Ribbons by Kantardzhieva, A, Peppi, M, Lane, W. S, Sewell, W. F

“…The synaptic ribbon is an electron-dense structure found in hair cells and photoreceptors. The ribbon is surrounded by neurotransmitter-filled vesicles and…”
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Epo-induced erythroid maturation is dependent on Plcγ1 signaling by Schnöder, T M, Arreba-Tutusaus, P, Griehl, I, Bullinger, L, Buschbeck, M, Lane, S W, Döhner, K, Plass, C, Lipka, D B, Heidel, F H, Fischer, T

“…Erythropoiesis is a tightly regulated process. Development of red blood cells occurs through differentiation of hematopoietic stem cells (HSCs) into more…”
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Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase by Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Elledge, S. J., Conaway, R. C., Harper, J. W., Conaway, J. W.

“…The von Hippel-Lindau (VHL) tumor suppressor gene is mutated in most human kidney cancers. The VHL protein is part of a complex that includes Elongin B,…”
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A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm by Casolari, D. A., Nguyen, T., Butcher, C. M., Iarossi, D. G., Hahn, C. N., Bray, S. C., Neufing, P., Parker, W. T., Feng, J., Maung, K. Z. Y., Wee, A., Vidovic, L., Kok, C. H., Bardy, P. G., Branford, S., Lewis, I. D., Lane, S. W., Scott, H. S., Ross, D. M., D’Andrea, R. J.

“…We describe a novel ERBB1/EGFR somatic mutation (p. C329R; c.985 T > C) identified in a patient with JAK2 V617F Polycythaemia Vera (PV). This substitution…”
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Antiangiogenic Activity of the Cleaved Conformation of the Serpin Antithrombin by O'Reilly, Michael S., Pirie-Shepherd, Steven, Lane, William S., Folkman, Judah

“…Antithrombin, a member of the serpin family, functions as an inhibitor of thrombin and other enzymes. Cleavage of the carboxyl-terminal loop of antithrombin…”
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The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins by Reinberg, Danny, Orphanides, George, Wu, Wei-Hua, Lane, William S, Hampsey, Michael

“…The regulation of gene expression depends critically upon chromatin structure. Transcription of protein-coding genes can be reconstituted on naked DNA with…”
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A protein phosphatase functions to recycle RNA polymerase II by Cho, H, Kim, T K, Mancebo, H, Lane, W S, Flores, O, Reinberg, D

“…Transcription is regulated by the state of phosphorylation of a heptapeptide repeat known as the carboxy-terminal domain (CTD) present in the largest subunit…”
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Snf1: A Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription by Lo, Wan-Sheng, Duggan, Laura, N. C. Tolga Emre, Belotserkovskya, Rimma, Lane, William S., Shiekhattar, Ramin, Berger, Shelley L.

“…Modification of histones is an important element in the regulation of gene expression. Previous work suggested a link between acetylation and phosphorylation,…”
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Requirement of RSF and FACT for Transcription of Chromatin Templates in Vitro by LeRoy, Gary, Orphanides, George, Lane, William S., Reinberg, Danny

“…Transcription of naked DNA in vitro requires the general transcription factors and RNA polymerase II. However, this minimal set of factors is not sufficient…”
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Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles by CHICZ, R. M, URBAN, R. G, GORGA, J. C, VIGNALI, D. A. A, LANE, W. S, STROMINGER, J. L

“…Naturally processed peptides were acid extracted from immunoaffinity-purified HLA-DR2, DR3, DR4, DR7, and DR8. Using the complementary techniques of mass…”
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Identification of self peptides bound to purified HLA-B27 by Jardetzky, T. S, Lane, W. S, Robinson, R. A, Madden, D. R, Wiley, D. C

“…A pool of endogenous peptides bound to the human class I MHC molecule, HLA-B27, has been isolated. Microsequence analysis of the pool and of 11 HPLC-purified…”
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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response by Livingston, David M, Weaver, David T, Wu, Xiaohua, Ranganathan, Velvizhi, Weisman, David S, Heine, Walter F, Ciccone, David N, O'Neill, Ted B, Crick, Kindra E, Pierce, Kerry A, Lane, William S, Rathbun, Gary

“…Nijmegen breakage syndrome (NBS) is characterized by extreme radiation sensitivity, chromosomal instability and cancer. The phenotypes are similar to those of…”
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Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin by Fenteany, Gabriel, Standaert, Robert F., Lane, William S., Choi, Soongyu, Corey, E. J., Schreiber, Stuart L.

“…Lactacystin is a Streptomyces metabolite that inhibits cell cycle progression and induces neurite outgrowth in a murine neuroblastoma cell line…”
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A mammalian protein targeted by G1-arresting rapamycin-receptor complex by Brown, Eric J, Albers, Mark W, Bum Shin, Tae, ichikawa, Kazuo, Keith, Curtis T, Lane, William S, Schreiber, Stuart L

“…The structurally related natural products rapamycin and FK506 bind to the same intracellular receptor, FKBP12, yet the resulting complexes interfere with…”
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SR proteins: a conserved family of pre-mRNA splicing factors by ZAHLER, A. M, LANE, W. S, STOLK, J. A, ROTH, M. B

“…We demonstrate that four different proteins from calf thymus are able to restore splicing in the same splicing-deficient extract using several different…”
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Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes by Chong, C-E, Venugopal, P, Stokes, P H, Lee, Y K, Brautigan, P J, Yeung, D T O, Babic, M, Engler, G A, Lane, S W, Klingler-Hoffmann, M, Matthews, J M, D'Andrea, R J, Brown, A L, Hahn, C N, Scott, H S

“…Heterozygous GATA2 mutations underlie an array of complex hematopoietic and lymphatic diseases. Analysis of the literature reporting three recurrent GATA2…”
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Role of IRS-2 in insulin and cytokine signalling by Sun, Xiao Jian, Wang, Ling-Mei, Zhang, Yitao, Yenush, Lynne, Myers Jr, Martin G, Glasheen, Erin, Lane, William S, Pierce, Jacalyn H, White, Morris F

“…The protein IRS-1 acts as an interface between signalling proteins with Src-homology-2 domains (SH2 proteins) and the receptors for insulin, IGF-1, growth…”
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RBP1 Recruits the mSIN3-Histone Deacetylase Complex to the Pocket of Retinoblastoma Tumor Suppressor Family Proteins Found in Limited Discrete Regions of the Nucleus at Growth Arrest by Lai, Albert, Kennedy, Brian K., Barbie, David A., Bertos, Nicholas R., Yang, Xiang Jiao, Theberge, Marie-Christine, Tsai, Shih-Chang, Seto, Edward, Zhang, Yi, Kuzmichev, Andrei, Lane, William S., Reinberg, Danny, Harlow, Ed, Branton, Philip E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A serine kinase regulates intracellular localization of splicing factors in the cell cycle by Gui, Jian-Fang, Lane, William S, Fu, Xiang-Dong

“…Small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP splicing factors containing a serine/arginine-rich domain (SR proteins) concentrate in…”
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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes by Liu, J, Farmer, Jr, J D, Lane, W S, Friedman, J, Weissman, I, Schreiber, S L

“…Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their similar mechanisms of inhibition…”
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