Search Results - "Lane, Rebecca"
-
1
The role of mitochondrial dysfunction in age-related diseases
Published in Biochimica et biophysica acta (01-11-2015)“…The aging process is accompanied by the onset of disease and a general decline in wellness. Insights into the aging process have revealed a number of cellular…”
Get full text
Journal Article -
2
Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing
Published in Scientific reports (06-01-2015)“…Exosomes are vesicles which have garnered interest due to their diagnostic and therapeutic potential. Isolation of pure yields of exosomes from complex…”
Get full text
Journal Article -
3
Optimizing Size Exclusion Chromatography for Extracellular Vesicle Enrichment and Proteomic Analysis from Clinically Relevant Samples
Published in Proteomics (Weinheim) (01-04-2019)“…The field of extracellular vesicle (EV) research has rapidly expanded in recent years, with particular interest in their potential as circulating biomarkers…”
Get full text
Journal Article -
4
Purification Protocols for Extracellular Vesicles
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…This chapter provides a description of some of the standard methods used for the isolation of extracellular vesicles (EVs) from a variety of biological fluids,…”
Get more information
Journal Article -
5
Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysis
Published in Proteomics (Weinheim) (01-06-2024)“…Much recent research has been dedicated to exploring the utility of extracellular vesicles (EVs) as circulating disease biomarkers. Underpinning this work is…”
Get full text
Journal Article -
6
The Growing Impact of Micro/Nanomaterial‐Based Systems in Precision Oncology: Translating “Multiomics” Technologies
Published in Advanced functional materials (01-09-2020)“…The field of precision oncology is rapidly progressing toward integrated “multiomics” analysis of multiple molecular species (such as DNA, RNA, or proteins) to…”
Get full text
Journal Article -
7
DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans
Published in PLoS genetics (01-07-2016)“…Mitochondrial dysfunction underlies numerous age-related pathologies. In an effort to uncover how the detrimental effects of mitochondrial dysfunction might be…”
Get full text
Journal Article -
8
Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2020)“…Herpesviruses are ubiquitous human pathogens that cause a wide range of health complications. Currently, there is an incomplete understanding of cellular…”
Get full text
Journal Article -
9
Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma
Published in Science advances (01-02-2020)“…Monitoring targeted therapy in real time for cancer patients could provide vital information about the development of drug resistance and improve therapeutic…”
Get full text
Journal Article -
10
Systematic review of educational interventions to improve the menstrual health of young adolescent girls
Published in BMJ open (08-06-2022)“…ObjectivesTo systematically review interventions that include an element of menstrual education delivered to young adolescent girls.DesignThis was a systematic…”
Get full text
Journal Article -
11
Assessing the Feasibility of a Multicenter Transition Intervention Model Across Adolescent Secure Services in England (MOVING FORWARD): Protocol for a Feasibility Cluster Randomized Controlled Trial
Published in JMIR research protocols (01-10-2021)“…Background Young people moving from adolescent secure inpatient units to adult care in the United Kingdom have multiple and complex needs and are more likely…”
Get full text
Journal Article -
12
Early Mobilization in the Intensive Care Unit to Improve Long-Term Recovery
Published in Critical care clinics (01-10-2018)“…This article outlines the effect of early mobilization on the long-term recovery of patients following critical illness. It investigates the safety of…”
Get full text
Journal Article -
13
The effect of gun control laws on hospital admissions for children in the United States
Published in The journal of trauma and acute care surgery (01-10-2016)“…Gun control laws vary greatly between states within the United States. We hypothesized that states with strict gun laws have lower mortality and resource…”
Get full text
Journal Article -
14
Iatrogenic cardiac perforation due to pacemaker and defibrillator leads: a contemporary multicentre experience
Published in Europace (London, England) (22-11-2022)“…To determine the incidence, clinical features, management, and outcomes of pacemaker (PM) and implantable cardioverter-defibrillator (ICD) lead cardiac…”
Get full text
Journal Article -
15
Development of the A‐STEP: A new incremental maximal exercise capacity step test in cystic fibrosis
Published in Pediatric pulmonology (01-12-2021)“…Background Exercise testing is important in people with cystic fibrosis (pwCF). The aim was to develop an incremental maximal step test to assess exercise…”
Get full text
Journal Article -
16
Psychological Distress and Its Mediating Effect on Experiences of Online Risk: The Case for Vulnerable Young People
Published in Frontiers in education (Lausanne) (10-08-2022)“…There is strong evidence showing that vulnerable children and adolescents, such as children who are carers for their family, in care themselves, or who have a…”
Get full text
Journal Article -
17
Success and Safety of Endoscopic Retrograde Cholangiopancreatography in Children
Published in Journal of pediatric surgery (01-07-2017)“…Abstract Purpose Despite its diagnostic and therapeutic utility, endoscopic retrograde cholangiopancreatography (ERCP) is underutilized in children. Methods…”
Get full text
Journal Article -
18
Rationale and design of a randomised trial of intravenous iron in patients with heart failure
Published in Heart (British Cardiac Society) (01-12-2022)“…For patients with a reduced left ventricular ejection fraction (LVEF) heart failure with reduced ejection fraction (HFrEF) and iron deficiency, administration…”
Get more information
Journal Article -
19
Multiomics: The Growing Impact of Micro/Nanomaterial‐Based Systems in Precision Oncology: Translating “Multiomics” Technologies (Adv. Funct. Mater. 37/2020)
Published in Advanced functional materials (01-09-2020)“…In article number 1909306, Simon Puttick, Kevin M. Koo, Matt Trau, and co‐workers discuss the use of micro/nanomaterial‐based systems to facilitate…”
Get full text
Journal Article -
20
Feasibility of the A‐STEP for the assessment of exercise capacity in people with cystic fibrosis
Published in Pediatric pulmonology (01-10-2022)“…Objectives To evaluate feasibility of the Alfred Step Test Exercise Protocol (A‐STEP) for the assessment of exercise capacity in adults and children with…”
Get full text
Journal Article