Search Results - "Lane, Lucas A"

Physical Chemistry of Nanomedicine: Understanding the Complex Behaviors of Nanoparticles in Vivo by Lane, Lucas A, Qian, Ximei, Smith, Andrew M, Nie, Shuming

“…Nanomedicine is an interdisciplinary field of research at the interface of science, engineering, and medicine, with broad clinical applications ranging from…”
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SERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Tagging by Lane, Lucas A, Qian, Ximei, Nie, Shuming

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Stimuli-responsive nanoparticles for targeting the tumor microenvironment by Du, Jinzhi, Lane, Lucas A., Nie, Shuming

“…One of the most challenging and clinically important goals in nanomedicine is to deliver imaging and therapeutic agents to solid tumors. Here we discuss the…”
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Emergence of two near-infrared windows for in vivo and intraoperative SERS by Lane, Lucas A, Xue, Ruiyang, Nie, Shuming

“…[Display omitted] •The first NIR clear window (650–950nm) is far superior for in vivo and intraoperative optical imaging than visible light.•The second NIR…”
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AMP coated SERS NanoTags with hydrophobic locking: Maximizing brightness, stability, and cellular targetability by Lane, Lucas A., Zhang, Jinglei, Wang, Yiqing

“…[Display omitted] Developing innovative surface-enhanced Raman scattering (SERS) nanotags continues to attract significant attention due to their unparalleled…”
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Probing the biological obstacles of nanomedicine with gold nanoparticles by Li, Bin, Lane, Lucas A.

“…Despite massive growth in nanomedicine research to date, the field still lacks fundamental understanding of how certain physical and chemical features of a…”
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Compact and Blinking-Suppressed Quantum Dots for Single-Particle Tracking in Live Cells by Lane, Lucas A, Smith, Andrew M, Lian, Tianquan, Nie, Shuming

“…Quantum dots (QDs) offer distinct advantages over organic dyes and fluorescent proteins for biological imaging applications because of their brightness,…”
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Alternating stealth polymer coatings between administrations minimizes toxic and antibody immune responses towards nanomedicine treatment regimens by Li, Bin, Chu, Feng, Lu, Qian, Wang, Yiqing, Lane, Lucas A.

“…In efforts to achieve minimal systemic toxicity and high tumor delivery efficiencies in cancer therapy, various nanomedicine formulations having stealth…”
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Mapping the spatial distribution of charge carriers in quantum-confined heterostructures by Smith, Andrew M., Lane, Lucas A., Nie, Shuming

“…Quantum-confined nanostructures are considered ‘artificial atoms’ because the wavefunctions of their charge carriers resemble those of atomic orbitals. For…”
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Enhanced Detection Specificity and Sensitivity of Alzheimer’s Disease Using Amyloid-β-Targeted Quantum Dots by Quan, Li, Wu, Jiangxiao, Lane, Lucas A, Wang, Jianquan, Lu, Qian, Gu, Zheng, Wang, Yiqing

“…Diagnostics of Alzheimer’s disease (AD) commonly employ the use of fluorescent thioflavin derivatives having affinity for the amyloid-β (Aβ) proteins…”
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Method for Real-Time Tissue Quantification of Indocyanine Green Revealing Optimal Conditions for Near Infrared Fluorescence Guided Surgery by Wang, Ziyang, Ni, Kena, Zhang, Xudong, Ai, Shichao, Guan, Wenxian, Cai, Huiming, Wang, Yiqing, Lu, Qian, Lane, Lucas A

“…Near infrared fluorescence guided surgery (NIRFGS) offers better distinction between cancerous and normal tissues compared to surgeries relying on a surgeon’s…”
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Functionalized, Long-Circulating, and Ultrasmall Gold Nanocarriers for Overcoming the Barriers of Low Nanoparticle Delivery Efficiency and Poor Tumor Penetration by Lee, Kate Y. J, Lee, Gee Young, Lane, Lucas A, Li, Bin, Wang, Jianquan, Lu, Qian, Wang, Yiqing, Nie, Shuming

“…The development of sophisticated nanoplatforms for in vivo targeted delivery of therapeutic agents to solid tumors has the potential for not only improving…”
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An unusual role of folate in the self-assembly of heparin-folate conjugates into nanoparticles by Wang, Jianquan, Ma, Daoshuang, Lu, Qian, Wu, Shaoxiong, Lee, Gee Young, Lane, Lucas A, Li, Bin, Quan, Li, Wang, Yiqing, Nie, Shuming

“…Tumor targeting agents including antibodies, peptides, and small molecules, are often used to improve the delivery efficiency of nanoparticles. Despite…”
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Quantitative Examination of the Active Targeting Effect: The Key Factor for Maximal Tumor Accumulation and Retention of Short-Circulated Biopolymeric Nanocarriers by Wang, Jianquan, Lee, Gee Young, Lu, Qian, Peng, Xianghong, Wu, Jiangxiao, Wu, Siyuan, Kairdolf, Brad A, Nie, Shuming, Wang, Yiqing, Lane, Lucas A

“…Targeted and nontargeted biopolymeric nanoparticles with identical hydrodynamic sizes and surface charges were quantitatively examined in terms of the…”
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SERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Imaging by Lane, Lucas A, Qian, Ximei, Nie, Shuming

“…A look at how diagnostic and therapeutic nanoparticles have evolved in the field of biomedicine, science and engineering is presented. Topics addressed include…”
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