Search Results - "Landvik, Nina E."
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Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region
Published in Journal of human genetics (01-11-2012)“…Interleukin-1β (IL-1β), encoded by the IL1B gene, is a cytokine important in regulation of the inflammatory response. Elevated levels of IL1B expression have…”
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DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
Published in Cancer Immunology, Immunotherapy (01-02-2013)“…Epidemiologic and experimental evidences support the concept that inflammation promotes the development and progression of cancers. Interleukins (ILs) regulate…”
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A combination of functional polymorphisms in the CASP8 , MMP1 , IL10 and SEPS1 genes affects risk of non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-02-2011)“…Abstract Exposure to tobacco smoke as well as environmental and occupational factors is the major cause of lung cancer. Non-small cell lung cancer (NSCLC) is…”
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A specific interleukin-1B haplotype correlates with high levels of IL1B mRNA in the lung and increased risk of non-small cell lung cancer
Published in Carcinogenesis (New York) (01-07-2009)“…Epidemiological evidence suggests a relationship between chronic inflammation and lung cancer. Inflammation in the lung may be modulated by host genetic…”
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Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations
Published in International journal of cancer (15-04-2013)“…Genome‐wide association studies have demonstrated that genetic polymorphisms influence the risk of developing lung cancer. Nicotinic acetylcholine receptor…”
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The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung
Published in Carcinogenesis (New York) (01-08-2009)“…Genome-wide association studies have provided evidence that common variation at 5p15.33 [telomerase reverse transcriptase (TERT)-cleft lip and palate…”
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Functional characterization of polymorphisms in the human TFPI gene
Published in Biochemical and biophysical research communications (18-06-2010)“…Tissue factor pathway inhibitor (TFPI) is the primary physiological inhibitor of tissue factor (TF) induced coagulation. Low plasma TFPI levels have been shown…”
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Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: Possible implications for their mutagenic and carcinogenic effects
Published in Toxicology (Amsterdam) (07-03-2007)“…Abstract Nitrated-polycyclic aromatic hydrocarbons (nitro-PAHs) and diesel exhaust particle extracts (DEPE) induced apoptosis in Hepa1c1c7 cells with the…”
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Different mechanisms involved in apoptosis following exposure to benzo[ a]pyrene in F258 and Hepa1c1c7 cells
Published in Chemico-biological interactions (05-04-2007)“…The present study compares and elucidates possible mechanisms why B[ a]P induces different cell signals and triggers apparently different apoptotic pathways in…”
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1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells
Published in Toxicology and applied pharmacology (15-07-2008)“…Mechanistic studies of nitro-PAHs (polycyclic aromatic hydrocarbons) of interest might help elucidate which chemical characteristics are most important in…”
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Gene variants and lung cancer risk
Published in BMC proceedings (24-09-2010)“…Polymorphisms have been investigated to determine whether variations in phase I and phase II metabolism, DNA repair genes and inflammatory genes predict risk…”
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