Search Results - "Landrum, John T"

Biologic mechanisms of the protective role of lutein and Zeaxanthin in the eye by Krinsky, Norman I, Landrum, John T, Bone, Richard A

“…The macular region of the primate retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and…”
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Lutein, Zeaxanthin, and the Macular Pigment by Landrum, John T, Bone, Richard A

“…The predominant carotenoids of the macular pigment are lutein, zeaxanthin, and meso-zeaxanthin. The regular distribution pattern of these carotenoids within…”
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Comparison of Antioxidant Properties of Dehydrolutein with Lutein and Zeaxanthin, and their Effects on Cultured Retinal Pigment Epithelial Cells by Różanowska, Małgorzata B., Czuba-Pelech, Barbara, Landrum, John T., Różanowski, Bartosz

“…Dehydrolutein accumulates in substantial concentrations in the retina. The aim of this study was to compare antioxidant properties of dehydrolutein with other…”
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Efficacy of Diacetate Esters of Macular Carotenoids: Effect of Supplementation on Macular Pigment by Bone, Richard A., Mukherjee, Anirbaan, Landrum, John T.

“…The accumulation of the carotenoids lutein, zeaxanthin, and mesozeaxanthin in the center of the human retina, and known as the macula lutea or macular pigment,…”
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Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin by Bone, Richard A, Landrum, John T, Cao, Yisi, Howard, Alan N, Alvarez-Calderon, Francesca

“…Age-related macular degeneration (AMD) is a disease with multiple risk factors, many of which appear to involve oxidative stress. Macular pigment, with its…”
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Dose-dependent response of serum lutein and macular pigment optical density to supplementation with lutein esters by Bone, Richard A., Landrum, John T.

“…We conducted a study to determine the effect of different doses of a lutein supplement on serum lutein concentration and macular pigment optical density…”
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Lutein and Zeaxanthin in the Eyes, Serum and Diet of Human Subjects by Bone, Richard A, Landrum, John T, Dixon, Zisca, Chen, Yin, Llerena, Cristina M

“…Inverse associations have been reported between the incidence of advanced, neovascular, age-related macular degeneration (AMD) and the combined lutein (L) and…”
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A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement by LANDRUM, JOHN T, BONE, RICHARD A, JOA, HILDA, KILBURN, MARK D, MOORE, LINDA L, SPRAGUE, KATHLEEN E

“…A low density of macular pigment may represent a risk factor for age-related macular degeneration (AMD) by permitting greater blue light damage. This study was…”
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Comments on Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: CREST - Report 1 by Bone, Richard A, Landrum, John T

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Direct Observation of Differences of Carotenoid Polyene Chain cis/trans Isomers Resulting from Structural Topology by Schenk, Emily R, Mendez, Vanesa, Landrum, John T, Ridgeway, Mark E, Park, Melvin A, Fernandez-Lima, Francisco

“…In the present paper, trapped ion mobility spectrometry (TIMS) and theoretical calculations have been used to study carotenoid geometrical motifs generated by…”
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Analysis of macular carotenoids in the developing macaque retina: The timeline of macular pigment development by Landrum, John T, Mendez, Vanesa, Cao, Yisi, Gomez, Ramon, Neuringer, Martha

“…In the mature retina, the components of the macular pigment, lutein (L), R,R-zeaxanthin (RRZ), R,S-zeaxanthin (RSZ, meso-zeaxanthin) are most concentrated in…”
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Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans by Bone, Richard A, Landrum, John T, Guerra, Luis H, Ruiz, Camilo A

“…Age-related macular degeneration (AMD) is thought to be the result of a lifetime of oxidative insult that results in photoreceptor death within the macula…”
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Heterochromatic flicker photometry by Bone, Richard A., Landrum, John T.

“…Measurement of the macular pigment optical density (MPOD) by heterochromatic flicker photometry (HFP) is accomplished by viewing a small circular stimulus that…”
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Dose-Ranging Study of Lutein Supplementation in Persons Aged 60 Years or Older by Rosenthal, Julie M, Kim, Jonghyeon, de Monastario, Francisco, Thompson, Darby J. S, Bone, Richard A, Landrum, John T, de Moura, Fabiana F, Khachik, Frederick, Chen, Huiping, Schleicher, Rosemary L, Ferris, Frederick L., III, Chew, Emily Y

“…To examine the dose-response relationship between oral lutein supplementation and serum lutein concentrations in persons aged 60 years and older, with or…”
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The conformation of end-groups is one determinant of carotenoid topology suitable for high fidelity molecular recognition: A study of β- and ε-end-groups by Landrum, John T., Chatfield, David C., Mebel, Alex M., Alvarez-Calderon, Francesca, Fernandez, Melissa V.

“…Conformation affects a carotenoid’s ability to bind selectively to proteins. We calculated adiabatic energy profiles for rotating the ring end-groups around…”
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Carotenoids. Guest editors' introduction by Landrum, John T, Wang, Xiang-Dong, Wurtzel, Eleanore T

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Distribution of Lutein and Zeaxanthin Stereoisomers in the Human Retina by BONE, RICHARD A., LANDRUM, JOHN T., FRIEDES, LARRY M., GOMEZ, CHRISTINA M., KILBURN, MARK D., MENENDEZ, EUGENIO, VIDAL, IVONNE, WANG, WEILI

“…The distribution of macular pigment stereoisomers in the human retina has been mapped and a pathway to account for the presence of the non-dietary…”
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Highlight on carotenoids by Mayne, Susan T.

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Macular pigment and the edge hypothesis of flicker photometry by Bone, Richard A., Landrum, John T., Gibert, Jorge C.

“…Heterochromatic flicker photometry is commonly used to measure macular pigment optical density (MPOD) in the human retina. It has been proposed, and accepted…”
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Methodologies for the measurement of the macular pigment by Landrum, John T., van Kuijk, Frederik J.G.M

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