Search Results - "Landro, A."
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A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels
Published in Nature medicine (01-09-2017)“…On the basis of new mechanistic studies of a mutant form of the apolipoprotein apoC-III that protects against coronary heart disease, Khetarpal et al. have…”
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2
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
Published in Biochemical journal (01-03-2016)“…AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that serves as a pleotropic regulator of whole body energy homoeostasis. AMPK exists…”
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3
Target-controlled infusion during MitraClip procedures in deep-sedation with spontaneous breathing
Published in European review for medical and pharmacological sciences (01-11-2022)“…Percutaneous mitral valve repair with the MitraClip system is an alternative procedure for high-risk patients not suitable for conventional surgery. The…”
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4
The constellation of dietary factors in adolescent acne: a semantic connectivity map approach
Published in Journal of the European Academy of Dermatology and Venereology (01-01-2016)“…Background Different lifestyle and dietetic factors have been linked with the onset and severity of acne. Objective To assess the complex interconnection…”
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5
Hidradenitis suppurativa epidemiology: from the first Italian registry in 2009 to the most recent epidemiology updates – Italian Registry Hidradenitis Suppurativa project 2
Published in Journal of the European Academy of Dermatology and Venereology (01-10-2019)“…Background The incidence of hidradenitis suppurativa (HS) is still not fully established with only a few studies reporting its estimates. Prevalence estimates…”
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New insights into potential risk factors and associations in genital lichen sclerosus: Data from a multicentre Italian study on 729 consecutive cases
Published in Journal of the European Academy of Dermatology and Venereology (01-04-2017)“…Background Limited data are available on risk factors associated with lichen sclerosus and no data are available on gender differences in genital lichen…”
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An original exploration of genital lichen sclerosus: the semantic connectivity map
Published in Journal of the European Academy of Dermatology and Venereology (01-02-2019)Get full text
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Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis
Published in Biochemical journal (01-02-2012)“…GK (glucokinase) is an enzyme central to glucose metabolism that displays positive co-operativity to substrate glucose. Small-molecule GKAs (GK activators)…”
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9
Persistent leukoderma after henna tattoo
Published in Contact dermatitis (01-02-2007)Get full text
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10
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
Published in Cell (18-10-1996)“…An estimated 1% of the global human population is infected by hepatitis C viruses (HCVs), and there are no broadly effective treatments for the debilitating…”
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11
Allergic reaction with persistent hypopigmentation due to temporary tattoing with henna in a baby
Published in Contact dermatitis (01-06-2005)Get full text
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Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells
Published in Journal of Virology (01-05-1997)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
'Lucky Luke' contact dermatitis from diapers with negative patch tests
Published in Contact dermatitis (01-01-2002)Get full text
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14
Metal-Binding Site in a Class I tRNA Synthetase Localized to a Cysteine Cluster Inserted Into Nucleotide-Binding Fold
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1993)“…The 10 class I aminoacyl-tRNA synthetases share a common N-terminal nucleotide-binding fold. Idiosyncratic polypeptide insertions into this fold introduce…”
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15
The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: Mechanistic and crystallographic evidence for stereospecific alkylation by (R)-.alpha.-phenylglycidate
Published in Biochemistry (Easton) (01-01-1994)“…The mechanism of irreversible inactivation of mandelate racemase (MR) from Pseudomonas putida by alpha-phenylglycidate (alpha PGA) has been investigated…”
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16
Mechanistic Role of an NS4A Peptide Cofactor with the Truncated NS3 Protease of Hepatitis C Virus: Elucidation of the NS4A Stimulatory Effect via Kinetic Analysis and Inhibitor Mapping
Published in Biochemistry (Easton) (05-08-1997)“…Infection by hepatitis C viruses (HCVs) is a serious medical problem with no broadly effective treatment available for the progression of chronic hepatitis…”
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17
Warty linear streaks of the palm and sole: possible late manifestations of incontinentia pigmenti
Published in British journal of dermatology (1951) (01-11-2000)Get full text
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18
Zinc-dependent cell growth conferred by mutant tRNA synthetase
Published in The Journal of biological chemistry (12-08-1994)“…We present evidence that zinc bound near the C terminus of a long tRNA synthetase polypeptide, and at a location far in the sequence from the catalytic domain,…”
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19
Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms
Published in Structure (London) (05-08-2014)“…AMP-activated protein kinase (AMPK) is a principal metabolic regulator affecting growth and response to cellular stress. Comprised of catalytic and regulatory…”
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Mechanism of the reaction catalyzed by mandelate racemase. 3. Asymmetry in reactions catalyzed by the H297N mutant
Published in Biochemistry (Easton) (01-09-1991)“…The two preceding papers [Powers, V. M., Koo, C. W., Kenyon, G. L., Gerlt, J. A., & Kozarich, J. W. (1991) Biochemistry (first paper of three in this issue);…”
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