Search Results - "Landomiel, Flavie"

Biased Signaling and Allosteric Modulation at the FSHR by Landomiel, Flavie, De Pascali, Francesco, Raynaud, Pauline, Jean-Alphonse, Frédéric, Yvinec, Romain, Pellissier, Lucie P, Bozon, Véronique, Bruneau, Gilles, Crépieux, Pascale, Poupon, Anne, Reiter, Eric

“…Knowledge on G protein-coupled receptor (GPCRs) structure and mechanism of activation has profoundly evolved over the past years. The way drugs targeting this…”
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Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor by De Pascali, Francesco, Ayoub, Mohammed Akli, Benevelli, Riccardo, Sposini, Silvia, Lehoux, Jordan, Gallay, Nathalie, Raynaud, Pauline, Landomiel, Flavie, Jean-Alphonse, Frédéric, Gauthier, Christophe, Pellissier, Lucie P., Crépieux, Pascale, Poupon, Anne, Inoue, Asuka, Joubert, Nicolas, Viaud-Massuard, Marie-Claude, Casarini, Livio, Simoni, Manuela, Hanyaloglu, Aylin C., Nataraja, Selva G., Yu, Henry N., Palmer, Stephen S., Yvinec, Romain, Reiter, Eric

“…Follicle-stimulating hormone receptor (FSHR) plays a key role in reproduction through the activation of multiple signaling pathways. Low molecular weight (LMW)…”
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Follicle-Stimulating Hormone Receptor: Advances and Remaining Challenges by De Pascali, Francesco, Tréfier, Aurélie, Landomiel, Flavie, Bozon, Véronique, Bruneau, Gilles, Yvinec, Romain, Poupon, Anne, Crépieux, Pascale, Reiter, Eric

“…Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR)…”
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β-arrestin signalling and bias in hormone-responsive GPCRs by Reiter, Eric, Ayoub, Mohammed Akli, Pellissier, Lucie P., Landomiel, Flavie, Musnier, Astrid, Tréfier, Aurélie, Gandia, Jorge, De Pascali, Francesco, Tahir, Shifa, Yvinec, Romain, Bruneau, Gilles, Poupon, Anne, Crépieux, Pascale

“…G protein-coupled receptors (GPCRs) play crucial roles in the ability of target organs to respond to hormonal cues. GPCRs’ activation mechanisms have long been…”
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Unraveling the molecular architecture of a G protein-coupled receptor/β-arrestin/Erk module complex by Bourquard, Thomas, Landomiel, Flavie, Reiter, Eric, Crépieux, Pascale, Ritchie, David W., Azé, Jérôme, Poupon, Anne

“…β-arrestins serve as signaling scaffolds downstream of G protein-coupled receptors and thus play a crucial role in a plethora of cellular processes. Although…”
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Biased signalling in follicle stimulating hormone action by Landomiel, Flavie, Gallay, Nathalie, Jégot, Gwenhael, Tranchant, Thibaud, Durand, Guillaume, Bourquard, Thomas, Crépieux, Pascale, Poupon, Anne, Reiter, Eric

“…•FSHR-induced signalling is a highly complex process that is not limited to coupling with the Gαs–cAMP–PKA pathway.•A specific subset of GPCR conformations are…”
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Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays by Ayoub, Mohammed Akli, Landomiel, Flavie, Gallay, Nathalie, Jégot, Gwenhael, Poupon, Anne, Crépieux, Pascale, Reiter, Eric

“…Gonadotropin receptors belong to the super family of G protein-coupled receptors and mediate the physiological effects of follicle-stimulating hormone (FSHR)…”
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G protein‐dependent signaling triggers a β‐arrestin‐scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation by Trefier, Aurelie, Musnier, Astrid, Landomiel, Flavie, Bourquard, Thomas, Boulo, Thomas, Ayoub, Mohammed Akli, Leon, Kelly, Bruneau, Gilles, Chevalier, Manon, Durand, Guillaume, Blache, Marie‐Claire, Inoue, Asuka, Fontaine, Joel, Gauthier, Christophe, Tesseraud, Sophie, Reiter, Eric, Poupon, Anne, Crepieux, Pascale

“…Many interaction partners of β‐arrestins intervene in the control of mRNA translation. However, how β‐arrestins regulate this cellular process has been poorly…”
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Unraveling the molecular architecture of a G protein-coupled receptor/[beta]-arrestin/Erk module complex by Bourquard, Thomas, Landomiel, Flavie, Reiter, Eric, Crépieux, Pascale, Ritchie, David W, Azé, Jérôme, Poupon, Anne

“…β-arrestins serve as signaling scaffolds downstream of G protein-coupled receptors, and thus play a crucial role in a plethora of cellular processes. Although…”
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Follicle-stimulating hormone receptor: Advances and remaining challenges by De Pascali, Francesco, Tréfier, Aurélie, Landomiel, Flavie, Bozon, Véronique, Bruneau, Gilles, Yvinec, Romain, Poupon, Anne, Crépieux, Pascale, Reiter, Eric

“…In: Arun K. Shukla (ed.), dir., G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A (p. 1-58). International Review…”
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