Search Results - "Landman, Nick"

Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma by Landman, Nick, Hulsman, Danielle, Badhai, Jitendra, Kopparam, Jawahar, Puppe, Julian, Pandey, Gaurav Kumar, van Lohuizen, Maarten

“…Background More than half of mesothelioma tumours show alterations in the tumour suppressor gene BAP1 . BAP1-deficient mesothelioma is shown to be sensitive to…”
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Retinoids and EZH2 inhibitors cooperate to orchestrate anti-oncogenic effects on bladder cancer cells by Ozgun, Gizem, Yaras, Tutku, Akman, Burcu, Özden-Yılmaz, Gülden, Landman, Nick, Karakülah, Gökhan, van Lohuizen, Maarten, Senturk, Serif, Erkek-Ozhan, Serap

“…The highly mutated nature of bladder cancers harboring mutations in chromatin regulatory genes opposing Polycomb-mediated repression highlights the importance…”
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Abstract 175: Mechanical transduction mediated by Integrin-ILK dependent actin dynamics drives stem-plasticity leading experimental metastatic colonization of prostate cancer leading experimental metastatic colonization of prostate cancer by Chen, Lanpeng, Coppola, Stefano, Landman, Nick, Groenewoud, Arwin, Schmidt, Thomas, Snaar-Jagalska, B.Ewa

“…Incurable bone metastasis is a main cause of death in prostate cancer. Metastasis is believed to be initiated by a small subpopulation of cancer cells termed…”
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Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma by Badhai, Jitendra, Landman, Nick, Pandey, Gaurav Kumar, Song, Ji-Ying, Hulsman, Danielle, Krijgsman, Oscar, Chandrasekaran, Gayathri, Berns, Anton, van Lohuizen, Maarten

“…Malignant mesothelioma is a highly aggressive tumor with a survival of only 4-18 months after diagnosis. Treatment options for this disease are limited. Immune…”
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Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma by Pandey, Gaurav Kumar, Landman, Nick, Neikes, Hannah K., Hulsman, Danielle, Lieftink, Cor, Beijersbergen, Roderick, Kolluri, Krishna Kalyan, Janes, Sam M., Vermeulen, Michiel, Badhai, Jitendra, van Lohuizen, Maarten

“…More than half of patients with malignant mesothelioma show alterations in the BAP1 tumor-suppressor gene. Being a member of the Polycomb repressive…”
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