Search Results - "Landman, Allison"

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance by Das Thakur, Meghna, Salangsang, Fernando, Landman, Allison S., Sellers, William R., Pryer, Nancy K., Levesque, Mitchell P., Dummer, Reinhard, McMahon, Martin, Stuart, Darrin D.

“…BRAF inhibitors such as vemurafenib have shown promising effects in patients with BRAF-mutant melanomas, but the tumours generally develop resistance;…”
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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage by Berman, Seth D, Calo, Eliezer, Landman, Allison S, Danielian, Paul S, Miller, Emily S, West, Julie C, Fonhoue, Borel Djouedjong, Caron, Alicia, Bronson, Roderick, Bouxsein, Mary L, Mukherjee, Siddhartha, Lees, Jacqueline A

“…Mutation of the RB-1 and p53 tumor suppressors is associated with the development of human osteosarcoma. With the goal of generating a mouse model of this…”
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Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase by van Veen, J Edward, Scherzer, Michael, Boshuizen, Julia, Chu, Mollee, Liu, Annie, Landman, Allison, Green, Shon, Trejo, Christy, McMahon, Martin

“…Human lung adenocarcinoma exhibits a propensity for de-differentiation, complicating diagnosis and treatment, and predicting poorer patient survival. In…”
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Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration by Joyce, Peter I, Fratta, Pietro, Landman, Allison S, Mcgoldrick, Philip, Wackerhage, Henning, Groves, Michael, Busam, Bharani Shiva, Galino, Jorge, Corrochano, Silvia, Beskina, Olga A, Esapa, Christopher, Ryder, Edward, Carter, Sarah, Stewart, Michelle, Codner, Gemma, Hilton, Helen, Teboul, Lydia, Tucker, Jennifer, Lionikas, Arimantas, Estabel, Jeanne, Ramirez-Solis, Ramiro, White, Jacqueline K, Brandner, Sebastian, Plagnol, Vincent, Bennet, David L H, Abramov, Andrey Y, Greensmith, Linda, Fisher, Elizabeth M C, Acevedo-Arozena, Abraham

“…Zinc finger motifs are distributed amongst many eukaryotic protein families, directing nucleic acid-protein and protein-protein interactions. Zinc finger…”
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SSO 2024 by Landman, Allison

“…In a secondary analysis of the phase 2 adaptively randomised I-SPY2 trial presented by Judy C Boughey (Mayo Clinic, Rochester, MN, USA), outcomes were compared…”
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2023 ASCO Annual Meeting by Landman, Allison

“…Neoadjuvant treatment in lung cancer Combining neoadjuvant pembrolizumab and ramucirumab in patients with PD-L1-positive, resectable, stage IB–IIIA…”
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Mechanisms of Rad52-Independent Spontaneous and UV-Induced Mitotic Recombination in Saccharomyces cerevisiae by Coïc, Eric, Feldman, Taya, Landman, Allison S, Haber, James E

“…In wild-type diploid cells, heteroallelic recombination between his4A and his4C alleles leads mostly to His+ gene conversions that have a parental…”
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2021 World Conference on Lung Cancer by Landman, Allison

“…POSEIDON Melissa Johnson (Sarah Cannon Research Institute, Nashville, TN, USA) presented results from a randomised, open-label, phase 3 study of 1013 patients…”
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ESTRO 2020 Online Congress by Landman, Allison

“…In a study presented by Thierry De Baère (Institut Gustave Roussy, Villejuif, France), NBTXR3 at four dose levels (10%, 15%, 22%, and 33% of tumour volume) was…”
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The G1 Cyclin Cln3 Promotes Cell Cycle Entry via the Transcription Factor Swi6 by Wijnen, Herman, Landman, Allison, Futcher, Bruce

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Global cancer surgery: a vital service to eliminate false economy by Landman, Allison, Collingridge, David

“…8 years on from publication of the first surgery Commission in The Lancet Oncology, some progress has been made, such as the launch of WHO's Breast Health…”
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49th SIOP Congress by Landman, Allison

“…Omitting radiotherapy for Wilm's tumour Xiaofei Sun (Sun Yat Sen University Cancer Center, Guangzhou, China) presented interim results from a multicentre,…”
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European Society of Medical Oncology 2016 Congress by Landman, Allison

“…Selinexor in gynaecological cancer Treatment with selinexor, a first-in-class inhibitor of the nuclear export protein XPO1, led to disease control and overall…”
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2016 ASCO Gastrointestinal Cancers Symposium by Landman, Allison

“…GATSBY trial Results from the adaptive phase 2/3 randomised GATSBY trial presented by Yoon-Koo Kang (University of Ulsan College of Medicine, Seoul, South…”
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Treating childhood cancer: a necessity not a choice by Landman, Allison, Collingridge, David

“…Owing to population growth and inequitable access to cancer care, 80% of the global cancer burden–in terms of both incidence and mortality is estimated to fall…”
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16th World Conference on Lung Cancer by Landman, Allison

“…Suresh Ramalingam (Atlanta, GA, USA) presented data for an expansion cohort of AURA in which 60 patients with treatment-naive EGFR mutation-positive advanced…”
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Working together to reduce the burden of pancreatic cancer by Landman, Allison, Feetham, Laura, Stuckey, Daniel

“…The global incidence of pancreatic cancer in 2017 was 5·7 per 100 000 person-years, up from 5·0 per 100 000 person-years in 1990; the number of deaths also…”
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A genetic modifier suggests that endurance exercise exacerbates Huntington's disease by Corrochano, Silvia, Blanco, Gonzalo, Williams, Debbie, Wettstein, Jessica, Simon, Michelle, Kumar, Saumya, Moir, Lee, Agnew, Thomas, Stewart, Michelle, Landman, Allison, Kotiadis, Vassilios N, Duchen, Michael R, Wackerhage, Henning, Rubinsztein, David C, Brown, Steve D M, Acevedo-Arozena, Abraham

“…Abstract Polyglutamine expansions in the huntingtin gene cause Huntington's disease (HD). Huntingtin is ubiquitously expressed, leading to pathological…”
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Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAF V600E oncoprotein kinase by van Veen, J Edward, Scherzer, Michael, Boshuizen, Julia, Chu, Mollee, Liu, Annie, Landman, Allison, Green, Shon, Trejo, Christy, McMahon, Martin

“…Human lung adenocarcinoma exhibits a propensity for de-differentiation, complicating diagnosis and treatment, and predicting poorer patient survival. In…”
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The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6 by Wijnen, Herman, Landman, Allison, Futcher, Bruce

“…In Saccharomyces cerevisiae (budding yeast), commitment to cell division in late G(1) is promoted by the G(1) cyclin Cln3 and its associated cyclin-dependent…”
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