Search Results - "Landgraf, Matthias"
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1
Regulation of neuronal development and function by ROS
Published in FEBS letters (01-03-2018)“…Reactive oxygen species (ROS) have long been studied as destructive agents in the context of nervous system ageing, disease and degeneration. Their roles as…”
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2
Neurogenesis reunited
Published in eLife (15-03-2016)“…Experiments on fruit flies are shedding new light on the evolution and development of the nervous system in metamorphosing insects…”
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3
Plug-and-Play Genetic Access to Drosophila Cell Types using Exchangeable Exon Cassettes
Published in Cell reports (Cambridge) (03-03-2015)“…Genetically encoded effectors are important tools for probing cellular function in living animals, but improved methods for directing their expression to…”
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4
Balance of activity during a critical period tunes a developing network
Published in eLife (09-01-2024)“…Developing neural circuits are influenced by activity and are especially sensitive to changes in activity during critical periods (CPs) of development. Changes…”
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5
Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila
Published in eLife (17-12-2018)“…Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the…”
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6
Nitric oxide mediates activity-dependent change to synaptic excitation during a critical period in Drosophila
Published in Scientific reports (13-10-2021)“…The emergence of coordinated network function during nervous system development is often associated with critical periods. These phases are sensitive to…”
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7
Analyzing Major Track Quality Indices and Introducing a Universally Applicable TQI
Published in Applied sciences (01-12-2020)“…Adequate railway track condition is a prerequisite for safe and reliable railway operation. Many track quality indices (TQIs) have been developed with the aim…”
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8
Connectomics Analysis Reveals First-, Second-, and Third-Order Thermosensory and Hygrosensory Neurons in the Adult Drosophila Brain
Published in Current biology (17-08-2020)“…Animals exhibit innate and learned preferences for temperature and humidity—conditions critical for their survival and reproduction. Leveraging a whole-brain…”
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9
Selective Inhibition Mediates the Sequential Recruitment of Motor Pools
Published in Neuron (Cambridge, Mass.) (03-08-2016)“…Locomotor systems generate diverse motor patterns to produce the movements underlying behavior, requiring that motor neurons be recruited at various phases of…”
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10
A Methodology Linking Tamping Processes and Railway Track Behaviour
Published in Applied sciences (01-02-2023)“…Today’s railway transport is built upon high-performance infrastructure. Cost-effective yet sustainable infrastructure presumes tracks with a precise and…”
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11
Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…In recent years, Drosophila melanogaster has emerged as a powerful model for neuronal circuit development, pathology, and function. A major impediment to these…”
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12
Electrophysiological Validation of Monosynaptic Connectivity between Premotor Interneurons and the aCC Motoneuron in the Drosophila Larval CNS
Published in The Journal of neuroscience (31-08-2022)“…The connectome project aims to map the synaptic connectivity of entire larval and adult fly neural networks, which is essential for understanding nervous…”
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13
Critical periods in Drosophila neural network development: Importance to network tuning and therapeutic potential
Published in Frontiers in physiology (02-12-2022)“…Critical periods are phases of heightened plasticity that occur during the development of neural networks. Beginning with pioneering work of Hubel and Wiesel,…”
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14
Development of Connectivity in a Motoneuronal Network in Drosophila Larvae
Published in Current biology (02-03-2015)“…Much of our understanding of how neural networks develop is based on studies of sensory systems, revealing often highly stereotyped patterns of connections,…”
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15
Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system
Published in PLoS biology (22-09-2009)“…A fundamental strategy for organising connections in the nervous system is the formation of neural maps. Map formation has been most intensively studied in…”
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16
Structural homeostasis: compensatory adjustments of dendritic arbor geometry in response to variations of synaptic input
Published in PLoS biology (01-10-2008)“…As the nervous system develops, there is an inherent variability in the connections formed between differentiating neurons. Despite this variability, neural…”
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17
Reactive Oxygen Species Mediate Activity-Regulated Dendritic Plasticity Through NADPH Oxidase and Aquaporin Regulation
Published in Frontiers in cellular neuroscience (05-07-2021)“…Neurons utilize plasticity of dendritic arbors as part of a larger suite of adaptive plasticity mechanisms. This explicitly manifests with motoneurons in the…”
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18
Dendritic growth gated by a steroid hormone receptor underlies increases in activity in the developing Drosophila locomotor system
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2013)“…As animals grow, their nervous systems also increase in size. How growth in the central nervous system is regulated and its functional consequences are…”
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19
Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases
Published in Frontiers in cellular neuroscience (13-01-2023)“…Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals. An…”
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20
A Cartesian Coordinate Robot for Dispensing Fruit Fly Food
Published in Journal of open hardware (31-07-2018)“…The fruit fly, 'Drosophila melanogaster', continues to be one of the most widely used model organisms in biomedical research. Though chosen for its ease of…”
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