Search Results - "Landersdorfer, C"

Using machine learning to optimize antibiotic combinations: dosing strategies for meropenem and polymyxin B against carbapenem-resistant Acinetobacter baumannii by Smith, N.M., Lenhard, J.R., Boissonneault, K.R., Landersdorfer, C.B., Bulitta, J.B., Holden, P.N., Forrest, A., Nation, R.L., Li, J., Tsuji, B.T.

“…Increased rates of carbapenem-resistant strains of Acinetobacter baumannii have forced clinicians to rely upon last-line agents, such as the polymyxins, or…”
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Population Pharmacokinetic Comparison and Pharmacodynamic Breakpoints of Ceftazidime in Cystic Fibrosis Patients and Healthy Volunteers by BULITTA, J. B, LANDERSDORFER, C. B, HILTTNER, S. J, DRUSANO, G. L, KINZIG, M, HOLZGRABE, U, STEPHAN, U, SÖRGEL, F

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Evaluation of enrofloxacin use in koalas (Phascolarctos cinereus) via population pharmacokinetics and Monte Carlo simulation by Black, L. A, Landersdorfer, C. B, Bulitta, J. B, Griffith, J. E, Govendir, M

“…Clinically normal koalas (n = 6) received a single dose of intravenous enrofloxacin (10 mg/kg). Serial plasma samples were collected over 24 h, and…”
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Comparable Population Pharmacokinetics and Pharmacodynamic Breakpoints of Cefpirome in Cystic Fibrosis Patients and Healthy Volunteers by BULITTA, J. B, KINZIG, M, LANDERSDORFER, C. B, HOLZGRABE, U, STEPHAN, U, SÖRGEL, F

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New Semiphysiological Absorption Model To Assess the Pharmacodynamic Profile of Cefuroxime Axetil Using Nonparametric and Parametric Population Pharmacokinetics by BULITTA, J. B, LANDERSDORFER, C. B, KINZIG, M, HOLZGRABE, U, SORGEL, F

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Pharmacokinetics of polymyxin B in patients on continuous venovenous haemodialysis by Sandri, Ana M, Landersdorfer, Cornelia B, Jacob, Jovan, Boniatti, Márcio M, Dalarosa, Micheline G, Falci, Diego R, Behle, Tainá F, Saitovitch, David, Wang, Jiping, Forrest, Alan, Nation, Roger L, Zavascki, Alexandre P, Li, Jian

“…To evaluate the pharmacokinetics of polymyxin B in patients on continuous venovenous haemodialysis (CVVHD) after intravenous administration of unadjusted…”
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Pharmacokinetics and pharmacodynamics of antibiotics in intensive care by Sörgel, F, Höhl, R, Glaser, R, Stelzer, C, Munz, M, Vormittag, M, Kinzig, M, Bulitta, J, Landersdorfer, C, Junger, A, Christ, M, Wilhelm, M, Holzgrabe, U

“…Optimized dosage regimens of antibiotics have remained obscure since their introduction. During the last two decades pharmacokinetic(PK)-pharmacodynamic(PD)…”
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Shape does matter: short high-concentration exposure minimizes resistance emergence for fluoroquinolones in Pseudomonas aeruginosa by Rees, Vanessa E, Bulitta, Jürgen B, Nation, Roger L, Tsuji, Brian T, Sörgel, Fritz, Landersdorfer, Cornelia B

“…For fluoroquinolones, the area under the free plasma concentration-time curve divided by the MIC (fAUC/MIC) best predicts bacterial killing in mice and…”
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Evaluation of enrofloxacin use in koalas ( P hascolarctos cinereus ) via population pharmacokinetics and M onte C arlo simulation by Black, L. A., Landersdorfer, C. B., Bulitta, J. B., Griffith, J. E., Govendir, M.

“…Clinically normal koalas ( n  = 6) received a single dose of intravenous enrofloxacin (10 mg/kg). Serial plasma samples were collected over 24 h, and…”
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Reply to Pai by Landersdorfer, Cornelia B., Nation, Roger L., Forrest, Alan, Sandri, Ana M., Zavascki, Alexandre P., Li, Jian

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Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers by KRUEGER, Wolfgang A, BULITTA, Jurgen, KINZIG-SCHIPPERS, Martina, LANDERSDORFER, Cornelia, HOLZGRABE, Ulrike, NABER, Kurt G, DRUSANO, George L, SÖRGEL, Fritz

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First-Dose Pharmacokinetics of Lithium Carbonate in Children and Adolescents by FINDLING, Robert L, LANDERSDORFER, Cornelia B, FABER, Jon, TAYLOR-ZAPATA, Perdita, JUSKO, William J, KAFANTARIS, Vivian, PAVULURI, Mani, MCNAMARA, Nora K, MCCLELLAN, Jon, FRAZIER, Jean A, SIKICH, Linmarie, KOWATCH, Robert, LINGLER, Jacqui

“…This study examines the pharmacokinetics of oral doses of lithium carbonate immediate-release capsules after administration of 600 or 900 mg in children and…”
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Acrylamide: increased concentrations in homemade food and first evidence of its variable absorption from food, variable metabolism and placental and breast milk transfer in humans by Sörgel, Fritz, Weissenbacher, Rainer, Kinzig-Schippers, Martina, Hofmann, Annette, Illauer, Michael, Skott, Andreas, Landersdorfer, Cornelia

“…We have developed a liquid chromatography/mass spectrometry (LC-MS/MS) assay to determine acrylamide in various body fluids. The assay also allows the reliable…”
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Pharmakokinetik und Pharmakodynamik von Antibiotika in der Intensivmedizin by Sörgel, F., Höhl, R., Glaser, R., Stelzer, C., Munz, M., Vormittag, M., Kinzig, M., Bulitta, J., Landersdorfer, C., Junger, A., Christ, M., Wilhelm, M., Holzgrabe, U.

“…Zusammenfassung Die optimale Dosierung von Antibiotika ist seit ihrer Einführung unklar geblieben. In den letzten 20 Jahren wurden 3…”
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