Search Results - "Lanchote, Vera L"

Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli by Abichabki, Nathália, Zacharias, Luísa V., Moreira, Natália C., Bellissimo-Rodrigues, Fernando, Moreira, Fernanda L., Benzi, Jhohann R. L., Ogasawara, Tânia M. C., Ferreira, Joseane C., Ribeiro, Camila M., Pavan, Fernando R., Pereira, Leonardo R. L., Brancini, Guilherme T. P., Braga, Gilberto Ú. L., Zuardi, Antonio W., Hallak, Jaime E. C., Crippa, José A. S., Lanchote, Vera L., Cantón, Rafael, Darini, Ana Lúcia C., Andrade, Leonardo N.

“…This study aimed to assess the ultrapure cannabidiol (CBD) antibacterial activity and to investigate the antibacterial activity of the combination CBD +…”
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Omeprazole preferentially inhibits the metabolism of (+)‐(S)‐citalopram in healthy volunteers by Rocha, Adriana, Coelho, Eduardo B., Sampaio, Stefânia A., Lanchote, Vera L.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Citalopram (CITA) pharmacokinetics are enantioselective in healthy volunteers and the metabolism of (+)‐(S)‐CITA to…”
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Chronic ethanol consumption enhances phenylephrine-induced contraction in the isolated rat aorta by Tirapelli, Carlos R, Al-Khoury, Johny, Bkaily, Ghassan, D'Orléans-Juste, Pedro, Lanchote, Vera L, Uyemura, Sergio A, de Oliveira, Ana M

“…Changes in reactivity to phenylephrine in aortas isolated from 2-, 6-, and 10-week ethanol-treated rats and their age-matched control and isocaloric rats were…”
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Evaluation of potential herbal-drug interactions of a standardized propolis extract (EPP-AF®) using an in vivo cocktail approach by Cusinato, Diego A.C., Martinez, Edson Z., Cintra, Mônica T.C., Filgueira, Gabriela C.O., Berretta, Andresa A., Lanchote, Vera L., Coelho, Eduardo B.

“…Propolis has been employed extensively in many cultures since ancient times as antiseptic, wound healing, anti-pyretic and others due to its biological and…”
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Ethanol consumption enhances endothelin-1-induced contraction in the isolated rat carotid by Tirapelli, Carlos R, Casolari, Débora A, Montezano, Augusto C, Yogi, Alvaro, Tostes, Rita C, Legros, Eurode, D'Orléans-Juste, Pedro, Lanchote, Vera L, Uyemura, Sérgio A, de Oliveira, Ana M

“…We investigated the mechanisms involved in the enhancement of endothelin (ET)-1 vascular reactivity induced by ethanol consumption. Ethanol intake for 2, 6,…”
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A highly sensitive LC–MS–MS assay for analysis of midazolam and its major metabolite in human plasma: Applications to drug metabolism by Jabor, Valquiria A.P., Coelho, Eduardo B., dos Santos, Neife A.G., Bonato, Pierina S., Lanchote, Vera L.

“…The present report describes a rapid, selective and a highly sensitive assay for midazolam (MDZ) and its major metabolite 1-hydroxymidazolam (1-OH-MDZ) in…”
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Population pharmacokinetics of carvedilol enantiomers and their metabolites in healthy subjects and type-2 diabetes patients by Nardotto, Glauco H.B., Lanchote, Vera L., Coelho, Eduardo B., Della Pasqua, Oscar

“…Carvedilol, a drug available as a racemic mixture, is metabolised into hydroxyphenylcarvedilol (OHC) by CYP2D6 and O-desmethylcarvedilol (DMC) by CYP2C9…”
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Detection of allopurinol and oxypurinol in canine urine by HPLC/MS-MS: Focus on veterinary clinical pharmacokinetics by Godoy, Ana Leonor P.C., de Jesus, Clauceane, Gonçalves, Rafaela S., Azeredo, Francine Johansson, Rocha, Adriana, Marques, Maria P., Lanchote, Vera L., Larangeira, Daniela F., Barrouin-Melo, Stella Maria

“…•Concentrations of allopurinol and oxypurinol in canine urine were determined.•HPLC-MS/MS is suitable for allopurinol and oxypurinol quantification in canine…”
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Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis by Arroyo, Gianfranco, Bustos, Javier A, Lescano, Andres G, Gonzales, Isidro, Saavedra, Herbert, Rodriguez, Silvia, Pretell, E Javier, Bonato, Pierina S, Lanchote, Vera L, Takayanagui, Osvaldo M, Horton, John, Gonzalez, Armando E, Gilman, Robert H, Garcia, Hector H

“…Abstract Background The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole…”
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Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis by Garcia, Hector H., Lescano, Andres G., Lanchote, Vera L., Pretell, E. Javier, Gonzales, Isidro, Bustos, Javier A., Takayanagui, Osvaldo M., Bonato, Pierina S., Horton, John, Saavedra, Herbert, Gonzalez, Armando E., Gilman, Robert H.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The antiparasitic drugs albendazole and prazoquantel have been used together before for geohelminths, echinococcosis…”
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Post‐marketing assessment of generic tamoxifen in Brazilian breast cancer patients by Ximenez, João P., Lanchote, Vera L., Bello, Marcelo A., Iocken, Fernanda H. S., Obadia, Renata C. M., Sousa, Valéria P., Suarez‐Kurtz, Guilherme

“…Generic formulations of tamoxifen are commonly prescribed to oestrogen receptor‐positive breast cancer patients at the Brazilian National Cancer Institute…”
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Enantioselective analysis of ibuprofen in human plasma by anionic cyclodextrin-modified electrokinetic chromatography by Jabor, Valquíria A. P., Lanchote, Vera L., Bonato, Pierina S.

“…This paper reports the development of a rapid method for the enantioselective analysis of the nonsteroidal anti‐inflammatory drug ibuprofen in human plasma by…”
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Influence of chronic kidney disease and haemodialysis treatment on pharmacokinetics of nebivolol enantiomers by Neves, Daniel V., Lanchote, Vera L., Moysés Neto, Miguel, Cardeal da Costa, José A., Vieira, Carolina P., Coelho, Eduardo B.

“…Aim The present study evaluated the pharmacodynamics and pharmacokinetics of nebivolol enantiomers in patients with chronic kidney disease (CKD) and in…”
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Pharmacokinetics and pharmacodynamics of rocuronium in young adult and elderly patients undergoing elective surgery by Varrique, Renan M., Lauretti, Gabriela R., Matsumoto, Julia A., Lanchote, Vera L., de Moraes, Natalia V.

“…Objective To evaluate the impact of advanced age on rocuronium kinetic disposition in ASA I–III patients undergoing elective surgeries. Methods Young adult…”
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Effects of Type 2 Diabetes Mellitus in Patients on Treatment With Glibenclamide and Metformin on Carvedilol Enantiomers Metabolism by Nardotto, Glauco H. B., Coelho, Eduardo B., Paiva, Carlos E., Lanchote, Vera L.

“…Carvedilol is available in clinical practice as a racemate in which (S)‐(–)‐carvedilol is a β‐ and α1‐adrenergic antagonist and (R)‐(+)‐carvedilol is only an…”
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Busulfan dosing algorithm and sampling strategy in stem cell transplantation patients by Castro, Francine A., Piana, Chiara, Simões, Belinda P., Lanchote, Vera L., Della Pasqua, O.

“…Aim The aim of this investigation was to develop a model‐based dosing algorithm for busulfan and identify an optimal sampling scheme for use in routine…”
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Enantioselective analysis of citalopram and demethylcitalopram in human and rat plasma by chiral LC-MS/MS: Application to pharmacokinetics by Rocha, Adriana, Marques, Maria P., Coelho, Eduardo B., Lanchote, Vera L.

“…Citalopram (CITA) is available as a racemic mixture and as a pure enantiomer. Its antidepressive action is related to the (+)‐(S)‐CITA and to the metabolite…”
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Impact of fraction unbound, CYP3A, and CYP2D6 in vivo activities, and other potential covariates to the clearance of tramadol enantiomers in patients with neuropathic pain by de Moraes, Natália V., Lauretti, Gabriela R., Coelho, Eduardo B., Godoy, Ana Leonor P. C., Neves, Daniel V., Lanchote, Vera L.

“…The pharmacokinetics of tramadol is characterized by a large interindividual variability, which is partially attributed to polymorphic CYP2D6 metabolism. The…”
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Effect of Type 2 Diabetes Mellitus on the Pharmacokinetics of Metformin in Obese Pregnant Women by de Oliveira Baraldi, Cláudia, Moisés, Elaine C. D., de Jesus Ponte Carvalho, Teresa M., de Jesus Antunes, Natalícia, Lanchote, Vera L., Duarte, Geraldo, Cavalli, Ricardo Carvalho

“…Background and Objective The use of metformin throughout gestation by women with polycystic ovary syndrome (PCOS) and type 2 diabetes mellitus (T2DM)…”
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EFETIVIDADE DA TERAPIA ANTIMICROBIANA EM PACIENTE SÉPTICO GRANDE QUEIMADO COM DISFUNÇÃO RENAL E LESÃO OCULAR GRAVE EM TERAPIA INTENSIVA COM VANCOMICINA-PIPERACILINA/TAZOBACTANA ATRAVÉS DA ABORDAGEM FARMACOCINÉTICA‐FARMACODINÂMICA by Santos, Maria Severina, Duarte, Nilo J.C., Junior, João M. da Silva, Junior, Elson M. Silva, Sandre, Aline, Rocha, Adriana, Duarte, Alberto S.J., Gomez, David S., Lanchote, Vera L., Santos, Silvia R.C.J.

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