Time to earliest peak serum antibody response to influenza vaccine in the elderly

The earliest time at which serum antibody levels peak following administration of an influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 1 and 2 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses...

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Bibliographic Details
Published in:	Clinical and diagnostic laboratory immunology Vol. 4; no. 4; pp. 491 - 492
Main Authors:	Gross, P A, Russo, C, Dran, S, Cataruozolo, P, Munk, G, Lancey, S C
Format:	Journal Article
Language:	English
Published:	United States 01-07-1997
Subjects:	Aged Antibodies, Viral - blood Female Humans Influenza Vaccines - immunology Male Time Factors
Online Access:	Get full text
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Summary:	The earliest time at which serum antibody levels peak following administration of an influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 1 and 2 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91 (H1N1), A/Johannesburg/33/94 (H3N2), and B/Harbin/7/94 was used. The hemagglutination inhibition (HAI) antibody titers at 1 week after vaccination were significantly lower than the HAI titers at 2 weeks postvaccination for all three vaccine components.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	1071-412X 1098-6588
DOI:	10.1128/cdli.4.4.491-492.1997