Search Results - "Lana McMillan"
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Quantitative Mass Spectrometry by SILAC in Haloferax volcanii
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…The development of mass spectrometry (MS)-based proteomics methods has been critical in providing new insight about cellular processes and adaptations in all…”
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Multiplex quantitative SILAC for analysis of archaeal proteomes: a case study of oxidative stress responses
Published in Environmental microbiology (01-01-2018)“…Summary Stable isotope labelling of amino acids in cell culture (SILAC) is a quantitative proteomic method that can illuminate new pathways used by cells to…”
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Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents
Published in Applied and environmental microbiology (15-01-2016)“…Soluble inorganic pyrophosphatases (PPAs) that hydrolyze inorganic pyrophosphate (PPi) to orthophosphate (Pi) are commonly used to accelerate and detect…”
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4
GlpR is a direct transcriptional repressor of fructose metabolic genes in Haloferax volcanii
Published in Journal of bacteriology (01-09-2018)“…DeoR-type helix-turn-helix (HTH) domain proteins are transcriptional regulators of sugar and nucleoside metabolism in diverse bacteria and occur in select…”
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Molecular Factors of Hypochlorite Tolerance in the Hypersaline Archaeon Haloferax volcanii
Published in Genes (20-11-2018)“…Halophilic archaea thrive in hypersaline conditions associated with desiccation, ultraviolet (UV) irradiation and redox active compounds, and thus are…”
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429 Implementing a practical induction programme in a tertiary teaching hospital
Published in Archives of disease in childhood (01-07-2023)“…ObjectivesOur aim was to gather feedback about the original induction programme and make adjustments to deliver relevant content to trainees. New sessions were…”
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In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials
Published in mBio (10-03-2020)“…is an important nosocomial pathogen that causes approximately 500,000 cases of infection (CDI) and 29,000 deaths annually in the United States. Antibiotic use…”
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Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial
Published in The Lancet infectious diseases (09-08-2024)“…The rate of antibiotic resistance continues to grow, outpacing small-molecule-drug development efforts. Novel therapies are needed to combat this growing…”
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Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents
Published in Applied and environmental microbiology (06-11-2015)“…Soluble inorganic pyrophosphatases (PPAs) that hydrolyze inorganic pyrophosphate (PPi) to orthophosphate (Pi) are commonly used to accelerate and detect…”
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10
Multiplex quantitative SILAC for analysis of archaeal proteomes: a case study of oxidative stress responses: Multiplex SILAC for archaeal proteomics
Published in Environmental microbiology (29-12-2017)“…Not provided…”
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italic toggle="yes">In Vivo /italic> Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials
Published in mBio (01-04-2020)“…ABSTRACT Clostridioides difficile is an important nosocomial pathogen that causes approximately 500,000 cases of C. difficile infection (CDI) and 29,000 deaths…”
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