Search Results - "Lana, M."

Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease by Osborn, Lana M, Kamphuis, Willem, Wadman, Wytse J, Hol, Elly M

“…Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle decline in episodic memory followed by a more general decline in…”
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Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction by Orre, Marie, Kamphuis, Willem, Osborn, Lana M, Jansen, Anne H.P, Kooijman, Lieneke, Bossers, Koen, Hol, Elly M

“…Abstract Reactive astrocytes and microglia are associated with amyloid plaques in Alzheimer's disease (AD). Yet, not much is known about the molecular…”
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Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction by Xu, Yong, Nedungadi, Thekkethil P., Zhu, Liangru, Sobhani, Nasim, Irani, Boman G., Davis, Kathryn E., Zhang, Xiaorui, Zou, Fang, Gent, Lana M., Hahner, Lisa D., Khan, Sohaib A., Elias, Carol F., Elmquist, Joel K., Clegg, Deborah J.

“…Estrogens regulate body weight and reproduction primarily through actions on estrogen receptor-α (ERα). However, ERα-expressing cells mediating these effects…”
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Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort by Simuni, Tanya, Caspell-Garcia, Chelsea, Coffey, Christopher S, Weintraub, Daniel, Mollenhauer, Brit, Lasch, Shirley, Tanner, Caroline M, Jennings, Danna, Kieburtz, Karl, Chahine, Lana M, Marek, Kenneth

“…ObjectiveTo examine the baseline prevalence and longitudinal evolution in non-motor symptoms (NMS) in a prospective cohort of, at baseline, patients with de…”
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Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study by Siderowf, Andrew, Concha-Marambio, Luis, Lafontant, David-Erick, Farris, Carly M, Ma, Yihua, Urenia, Paula A, Nguyen, Hieu, Alcalay, Roy N, Chahine, Lana M, Foroud, Tatiana, Galasko, Douglas, Kieburtz, Karl, Merchant, Kalpana, Mollenhauer, Brit, Poston, Kathleen L, Seibyl, John, Simuni, Tanya, Tanner, Caroline M, Weintraub, Daniel, Videnovic, Aleksandar, Choi, Seung Ho, Kurth, Ryan, Caspell-Garcia, Chelsea, Coffey, Christopher S, Frasier, Mark, Oliveira, Luis M A, Hutten, Samantha J, Sherer, Todd, Marek, Kenneth, Soto, Claudio

“…Emerging evidence shows that α-synuclein seed amplification assays (SAAs) have the potential to differentiate people with Parkinson's disease from healthy…”
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Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice by Orre, Marie, Kamphuis, Willem, Osborn, Lana M, Melief, Jeroen, Kooijman, Lieneke, Huitinga, Inge, Klooster, Jan, Bossers, Koen, Hol, Elly M

“…Abstract Astrocytes and microglia become reactive in many neurological disorders resulting in phenotypic and functional alterations. Both cell types might also…”
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Mind-wandering while driving: The impact of fatigue, task length, and sustained attention abilities by Walker, Heather E.K., Trick, Lana M.

“…•Overall driving speeds increase as a function of time-on-task.•Ability to focus on the driving task decreases as a function of time-on-task.•Differences in…”
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Habitual food consumption, eating behavior and meal-timing among Jordanian adults with elevated Blood pressure: a cross-sectional population-based study by Alkhatib, Buthaina, Al-Shami, Islam, Agraib, Lana M

“…The prevalence of elevated blood pressure (BP) has been raised worldwide. Food consumption, eating habits, and nutritional lifestyle related to meal timing,…”
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Providing hope: influences of volunteer tourism on program youth by Olsen, Lana M., Andereck, Kathleen, Vogt, Christine

“…Global South youth are considered members of a host community and are receivers of volunteer tourism development programs. However, their perceptions have…”
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Prodromal α-Synucleinopathies by Chahine, Lana M.

“…ABSTRACT PURPOSE OF REVIEW This article describes prodromal α-synucleinopathies. RECENT FINDINGS The pathology underlying α-synucleinopathies, which include…”
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A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research by Simuni, Tanya, Chahine, Lana M, Poston, Kathleen, Brumm, Michael, Buracchio, Teresa, Campbell, Michelle, Chowdhury, Sohini, Coffey, Christopher, Concha-Marambio, Luis, Dam, Tien, DiBiaso, Peter, Foroud, Tatiana, Frasier, Mark, Gochanour, Caroline, Jennings, Danna, Kieburtz, Karl, Kopil, Catherine M, Merchant, Kalpana, Mollenhauer, Brit, Montine, Thomas, Nudelman, Kelly, Pagano, Gennaro, Seibyl, John, Sherer, Todd, Singleton, Andrew, Stephenson, Diane, Stern, Matthew, Soto, Claudio, Tanner, Caroline M, Tolosa, Eduardo, Weintraub, Daniel, Xiao, Yuge, Siderowf, Andrew, Dunn, Billy, Marek, Kenneth

“…Parkinson's disease and dementia with Lewy bodies are currently defined by their clinical features, with α-synuclein pathology as the gold standard to…”
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Driving in fog: The effects of driving experience and visibility on speed compensation and hazard avoidance by Mueller, Alexandra S., Trick, Lana M.

“…► Investigates effects of driving experience and visibility on driving behaviour. ► Drivers can reduce their speed in poor visibility to lower their risk of…”
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Photoreceptor regeneration occurs normally in microglia-deficient irf8 mutant zebrafish following acute retinal damage by Song, Ping, Parsana, Dhwani, Singh, Rupesh, Pollock, Lana M., Anand-Apte, Bela, Perkins, Brian D.

“…Microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. Following…”
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Triggers and alleviating factors for fatigue in Parkinson's disease by Lin, Iris, Edison, Briana, Mantri, Sneha, Albert, Steven, Daeschler, Margaret, Kopil, Catherine, Marras, Connie, Chahine, Lana M

“…Fatigue is common in Parkinson's Disease, but few effective treatments are available for it. Exploring triggers and alleviating factors, including effects of…”
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Sleep and circadian rhythms in the treatment, trajectory, and prevention of neurodegenerative disease by Wilckens, Kristine A., Chahine, Lana M.

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Physical Activity and the Risk of Parkinson Disease: Moving in the Right Direction by Chahine, Lana M., Darweesh, Sirwan K. L.

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Proposal for a Biologic Staging System of Parkinson’s Disease by Chahine, Lana M., Merchant, Kalpana, Siderowf, Andrew, Sherer, Todd, Tanner, Caroline, Marek, Kenneth, Simuni, Tanya

“…The Parkinson’s disease (PD) research field has seen the advent of several promising biomarkers and a deeper understanding of the clinical features of the…”
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Part 1: Executive Summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care by Neumar, Robert W, Shuster, Michael, Callaway, Clifton W, Gent, Lana M, Atkins, Dianne L, Bhanji, Farhan, Brooks, Steven C, de Caen, Allan R, Donnino, Michael W, Ferrer, Jose Maria E, Kleinman, Monica E, Kronick, Steven L, Lavonas, Eric J, Link, Mark S, Mancini, Mary E, Morrison, Laurie J, O’Connor, Robert E, Samson, Ricardo A, Schexnayder, Steven M, Singletary, Eunice M, Sinz, Elizabeth H, Travers, Andrew H, Wyckoff, Myra H, Hazinski, Mary Fran

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Primary cilia are present on endothelial cells of the hyaloid vasculature but are not required for the development of the blood-retinal barrier by Pollock, Lana M, Perkins, Brian, Anand-Apte, Bela

“…Endothelial cilia are found in a variety of tissues including the cranial vasculature of zebrafish embryos. Recently, endothelial cells in the developing mouse…”
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Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease by Caspell-Garcia, Chelsea, Simuni, Tanya, Tosun-Turgut, Duygu, Wu, I-Wei, Zhang, Yu, Nalls, Mike, Singleton, Andrew, Shaw, Leslie A, Kang, Ju-Hee, Trojanowski, John Q, Siderowf, Andrew, Coffey, Christopher, Lasch, Shirley, Aarsland, Dag, Burn, David, Chahine, Lana M, Espay, Alberto J, Foster, Eric D, Hawkins, Keith A, Litvan, Irene, Richard, Irene, Weintraub, Daniel

“…To assess the neurobiological substrate of initial cognitive decline in Parkinson's disease (PD) to inform patient management, clinical trial design, and…”
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