Search Results - "Lan, Yujia"

CellMarker: a manually curated resource of cell markers in human and mouse by Zhang, Xinxin, Lan, Yujia, Xu, Jinyuan, Quan, Fei, Zhao, Erjie, Deng, Chunyu, Luo, Tao, Xu, Liwen, Liao, Gaoming, Yan, Min, Ping, Yanyan, Li, Feng, Shi, Aiai, Bai, Jing, Zhao, Tingting, Li, Xia, Xiao, Yun

“…Abstract One of the most fundamental questions in biology is what types of cells form different tissues and organs in a functionally coordinated fashion…”
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Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines by Wang, Li, Zhao, Hongying, Li, Jing, Xu, Yingqi, Lan, Yujia, Yin, Wenkang, Liu, Xiaoqin, Yu, Lei, Lin, Shihua, Du, Michael Yifei, Li, Xia, Xiao, Yun, Zhang, Yunpeng

“…Epigenetic modifications play critical roles in modulating gene expression, yet their roles in regulatory networks in human cell lines remain poorly…”
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DiseaseEnhancer: a resource of human disease-associated enhancer catalog by Zhang, Guanxiong, Shi, Jian, Zhu, Shiwei, Lan, Yujia, Xu, Liwen, Yuan, Huating, Liao, Gaoming, Liu, Xiaoqin, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…Abstract Large-scale sequencing studies discovered substantial genetic variants occurring in enhancers which regulate genes via long range chromatin…”
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Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals by Xu, Jinyuan, Pang, Bo, Lan, Yujia, Dou, Renjie, Wang, Shuai, Kang, Shaobo, Zhang, Wanmei, Liu, Yuanyuan, Zhang, Yijing, Ping, Yanyan

“…High heterogeneity in genome and phenotype of cancer populations made it difficult to apply population-based common driver genes to the diagnosis and treatment…”
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Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis by Shi, Aiai, Yan, Min, Pang, Bo, Pang, Lin, Wang, Yihan, Lan, Yujia, Zhang, Xinxin, Xu, Jinyuan, Ping, Yanyan, Hu, Jing

“…Cellular states of different immune cells can affect the activity of the whole immune microenvironment. Here, leveraging reference profiles of microenvironment…”
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Dissecting the Invasion-Associated Long Non-coding RNAs Using Single-Cell RNA-Seq Data of Glioblastoma by Pang, Bo, Quan, Fei, Ping, Yanyan, Hu, Jing, Lan, Yujia, Pang, Lin

“…Glioblastoma (GBM) is characterized by rapid and lethal infiltration of brain tissue, which is the primary cause of treatment failure and deaths for GBM…”
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Nomograms for Predicting Axillary Lymph Node Status Reconciled With Preoperative Breast Ultrasound Images by Liu, Dongmei, Lan, Yujia, Zhang, Lei, Wu, Tong, Cui, Hao, Li, Ziyao, Sun, Ping, Tian, Peng, Tian, Jiawei, Li, Xia

“…The axillary lymph node (ALN) status of breast cancer patients is an important prognostic indicator. The use of primary breast mass features for the prediction…”
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Identification of a Six-lncRNA Signature With Prognostic Value for Breast Cancer Patients by Zhao, Erjie, Lan, Yujia, Quan, Fei, Zhu, Xiaojing, A, Suru, Wan, Linyun, Xu, Jinyuan, Hu, Jing

“…Breast cancer (BRCA) is the most common cancer and a major cause of death in women. Long non-coding RNAs (lncRNAs) are emerging as key regulators and have been…”
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Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma by Zhou, Yao, Wang, Shuai, Yan, Haoteng, Pang, Bo, Zhang, Xinxin, Pang, Lin, Wang, Yihan, Xu, Jinyuan, Hu, Jing, Lan, Yujia, Ping, Yanyan

“…Somatic copy-number alterations (SCNAs) are major contributors to cancer development that are pervasive and highly heterogeneous in human cancers. However, the…”
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A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs by Deng, Yulan, Luo, Shangyi, Zhang, Xinxin, Zou, Chaoxia, Yuan, Huating, Liao, Gaoming, Xu, Liwen, Deng, Chunyu, Lan, Yujia, Zhao, Tingting, Gao, Xu, Xiao, Yun, Li, Xia

“…Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However, very little is known about the…”
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Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis by Lan, Yujia, Zhao, Erjie, Zhang, Xinxin, Zhu, Xiaojing, Wan, Linyun, A, Suru, Ping, Yanyan, Wang, Yihan

“…Glioblastoma multiforme (GBM) is a highly, malignant tumor of the primary central nervous system. Patients diagnosed with this type of tumor have a poor…”
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Transcriptome analysis reveals a reprogramming energy metabolism-related signature to improve prognosis in colon cancer by Zhang, Xinxin, Xu, Jinyuan, Lan, Yujia, Guo, Fenghua, Xiao, Yun, Li, Yixue, Li, Xia

“…Although much progress has been made to improve treatment, colon cancer remains a leading cause of cancer death worldwide. Metabolic reprogramming is a…”
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Transcriptomic heterogeneity of driver gene mutations reveals novel mutual exclusivity and improves exploration of functional associations by Lan, Yujia, Liu, Wei, Zhang, Wanmei, Hu, Jing, Zhu, Xiaojing, Wan, Linyun, A, Suru, Ping, Yanyan, Xiao, Yun

“…Background Lung adenocarcinoma (LUAD), as the most common subtype of lung cancer, is the leading cause of cancer deaths in the world. The accumulation of…”
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Genome-wide DNA methylome reveals the dysfunction of intronic microRNAs in major psychosis by Zhao, Hongying, Xu, Jinyuan, Pang, Lin, Zhang, Yunpeng, Fan, Huihui, Liu, Ling, Liu, Tingting, Yu, Fulong, Zhang, Guanxiong, Lan, Yujia, Bai, Jing, Li, Xia, Xiao, Yun

“…DNA methylation is thought to be extensively involved in the pathogenesis of many diseases, including major psychosis. However, most studies focus on DNA…”
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Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes by Jiang, Zedong, Liao, Gaoming, Yang, Yiran, Lan, Yujia, Xu, Liwen, Yan, Min, Zhou, Yao, Zhu, Jiali, Liu, Wei, Bai, Jing, Xiao, Yun, Li, Xia

“…Somatic mutations accumulate over time in cancer cells as a consequence of mutational processes. However, the role of mutational processes in carcinogenesis…”
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Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids by Ping, Yanyan, Xu, Chaohan, Xu, Liwen, Liao, Gaoming, Zhou, Yao, Deng, Chunyu, Lan, Yujia, Yu, Fulong, Shi, Jian, Wang, Li, Xiao, Yun, Li, Xia

“…Engineered organoids by sequential introduction of key mutations could help modeling the dynamic cancer progression. However, it remains difficult to determine…”
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A comprehensive overview of lncRNA annotation resources by Xu, Jinyuan, Bai, Jing, Zhang, Xinxin, Lv, Yanling, Gong, Yonghui, Liu, Ling, Zhao, Hongying, Yu, Fulong, Ping, Yanyan, Zhang, Guanxiong, Lan, Yujia, Xiao, Yun, Li, Xia

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A comprehensive overview of lncRNA annotation resources by Xu, Jinyuan, Bai, Jing, Zhang, Xinxin, Lv, Yanling, Gong, Yonghui, Liu, Ling, Zhao, Hongying, Yu, Fulong, Ping, Yanyan, Zhang, Guanxiong, Lan, Yujia, Xiao, Yun, Li, Xia

“…Abstract Long noncoding RNAs (lncRNAs) are emerging as a class of important regulators participating in various biological functions and disease processes…”
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Breast cancer prognosis signature: linking risk stratification to disease subtypes by Yu, Fulong, Quan, Fei, Xu, Jinyuan, Zhang, Yan, Xie, Yi, Zhang, Jingyu, Lan, Yujia, Yuan, Huating, Zhang, Hongyi, Cheng, Shujun, Xiao, Yun, Li, Xia

“…Abstract Breast cancer is a very complex and heterogeneous disease with variable molecular mechanisms of carcinogenesis and clinical behaviors. The…”
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Comprehensive analysis of long noncoding RNA (lncRNA)-chromatin interactions reveals lncRNA functions dependent on binding diverse regulatory elements by Zhang, Guanxiong, Lan, Yujia, Xie, Aimin, Shi, Jian, Zhao, Hongying, Xu, Liwen, Zhu, Shiwei, Luo, Tao, Zhao, Tingting, Xiao, Yun, Li, Xia

“…Over the past decade, thousands of long noncoding RNAs (lncRNAs) have been identified, many of which play crucial roles in normal physiology and human disease…”
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