Search Results - "Lampi, Youlia"
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Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation
Published in Cells (Basel, Switzerland) (01-03-2023)“…In malignant cancer, excessive amounts of mutant p53 often lead to its aggregation, a feature that was recently identified as druggable. Here, we describe that…”
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Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice
Published in European journal of immunology (01-10-2018)“…Mucosa‐associated lymphoid tissue 1 (Malt1) regulates immune cell function by mediating the activation of nuclear factor κB (NF‐κB) signaling through both its…”
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Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways
Published in Human gene therapy (01-06-2014)“…Gene therapy of the lung has the potential to treat life-threatening diseases such as cystic fibrosis and α(1)-antitrypsin or surfactant deficiencies. A major…”
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