Search Results - "Lamouroux, Arthur"

Effects of Drugs Formerly Suggested for COVID-19 Repurposing on Pannexin1 Channels by Caufriez, Anne, Tabernilla, Andrés, Van Campenhout, Raf, Cooreman, Axelle, Leroy, Kaat, Sanz Serrano, Julen, Kadam, Prashant, Dos Santos Rodrigues, Bruna, Lamouroux, Arthur, Ballet, Steven, Vinken, Mathieu

“…Although many efforts have been made to elucidate the pathogenesis of COVID-19, the underlying mechanisms are yet to be fully uncovered. However, it is known…”
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Controlling Dipole Orientation through Curvature: Aromatic Foldamer Bent β‑Sheets and Helix–Sheet–Helix Architectures by Lamouroux, Arthur, Sebaoun, Laure, Wicher, Barbara, Kauffmann, Brice, Ferrand, Yann, Maurizot, Victor, Huc, Ivan

“…The helix, turn, and β-strand motifs of biopolymer folded structures have been found to prevail also in non-natural backbones. In contrast, foldamers with aryl…”
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Structure-Based Design and Synthesis of Stapled 10 Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases by Lamouroux, Arthur, Tournier, Malaury, Iaculli, Debora, Caufriez, Anne, Rusiecka, Olga M., Martin, Charlotte, Bes, Viviane, Carpio, Laureano E., Girardin, Yana, Loris, Remy, Tabernilla, Andrés, Molica, Filippo, Gozalbes, Rafael, Mayán, María D., Vinken, Mathieu, Kwak, Brenda R., Ballet, Steven

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Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release by Heremans, Julie, Chevillard, Lucie, Mannes, Morgane, Mangialetto, Jessica, Leroy, Kaat, White, Jacinta F., Lamouroux, Arthur, Vinken, Mathieu, Gardiner, James, Van Mele, Bruno, Van den Brande, Niko, Hoogenboom, Richard, Madder, Annemieke, Caveliers, Vicky, Mégarbane, Bruno, Hernot, Sophie, Ballet, Steven, Martin, Charlotte

“…Peptide-based hydrogels represent promising systems for the sustained release of different types of drugs, ranging from small molecules to biologicals. Aiming…”
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Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release by Heremans, Julie, Chevillard, Lucie, Mannes, Morgane, Mangialetto, Jessica, Leroy, Kaat, White, Jacinta, Lamouroux, Arthur, Vinken, Mathieu, Gardiner, James, van Mele, Bruno, van den Brande, Niko, Hoogenboom, Richard, Madder, Annemieke, Caveliers, Vicky, Mégarbane, Bruno, Hernot, Sophie, Ballet, Steven, Martin, Charlotte

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Structure-Based Design and Synthesis of Stapled 10Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases by Lamouroux, Arthur, Tournier, Malaury, Iaculli, Debora, Caufriez, Anne, Rusiecka, Olga M., Martin, Charlotte, Bes, Viviane, Carpio, Laureano E., Girardin, Yana, Loris, Remy, Tabernilla, Andrés, Molica, Filippo, Gozalbes, Rafael, Mayán, María D., Vinken, Mathieu, Kwak, Brenda R., Ballet, Steven

“…Following a rational design, a series of macrocyclic (“stapled”) peptidomimetics of 10Panx1, the most established peptide inhibitor of Pannexin1 (Panx1)…”
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Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design by Gimenez, Luis E., Martin, Charlotte, Yu, Jing, Hollanders, Charlie, Hernandez, Ciria C., Wu, Yiran, Yao, Deqiang, Han, Gye Won, Dahir, Naima S., Wu, Lijie, Van der Poorten, Olivier, Lamouroux, Arthur, Mannes, Morgane, Zhao, Suwen, Tourwé, Dirk, Stevens, Raymond C., Cone, Roger D., Ballet, Steven

“…Melanocortin 4 receptor (MC4-R) antagonists are actively sought for treating cancer cachexia. We determined the structures of complexes with PG-934 and…”
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Determination of structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10Panx1 by Caufriez, Anne, Lamouroux, Arthur, Martin, Charlotte, Iaculli, Debora, Ince Ergüç, Elif, Gozalbes, Rafael, Mayan, Maria D., Kwak, Brenda R., Tabernilla, Andrés, Vinken, Mathieu, Ballet, Steven

“…[Display omitted] •The half-life of 10Panx1 is circa 2 min in human plasma.•Asp8 and Gln3 were pinpointed as critical residues in the inhibition of Pannexin1…”
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Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure by Martin, Charlotte, Gimenez, Luis E, Williams, Savannah Y, Jing, Yu, Wu, Yiran, Hollanders, Charlie, Van der Poorten, Olivier, Gonzalez, Simon, Van Holsbeeck, Kevin, Previti, Santo, Lamouroux, Arthur, Zhao, Suwen, Tourwé, Dirk, Stevens, Raymond C, Cone, Roger D, Ballet, Steven

“…The melanocortin receptors (MC1R-MC5R) belong to class A G-protein-coupled receptors (GPCRs) and are known to have receptor-specific roles in normal and…”
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Determination of structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10 Panx1 by Caufriez, Anne, Lamouroux, Arthur, Martin, Charlotte, Iaculli, Debora, Ince Ergüç, Elif, Gozalbes, Rafael, Mayan, Maria D, Kwak, Brenda R, Tabernilla, Andrés, Vinken, Mathieu, Ballet, Steven

“…Pannexin1 channels facilitate paracrine communication and are involved in a broad spectrum of diseases. Attempts to find appropriate pannexin1 channel…”
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