Search Results - "Lamoreux, M. Lynn"

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles by Setty, Subba Rao Gangi, Tenza, Danièle, Truschel, Steven T, Chou, Evelyn, Sviderskaya, Elena V, Theos, Alexander C, Lamoreux, M Lynn, Di Pietro, Santiago M, Starcevic, Marta, Bennett, Dorothy C, Dell'Angelica, Esteban C, Raposo, Graça, Marks, Michael S

“…Hermansky-Pudlak syndrome (HPS) is a genetic disorder characterized by defects in the formation and function of lysosome-related organelles such as…”
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Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway by Hida, Tokimasa, Wakamatsu, Kazumasa, Sviderskaya, Elena V., Donkin, Andrew J., Montoliu, Lluis, Lynn Lamoreux, M., Yu, Bin, Millhauser, Glenn L., Ito, Shosuke, Barsh, Gregory S., Jimbow, Kowichi, Bennett, Dorothy C.

“…Summary Melanocortin‐1 receptor (MC1R) and its ligands, α‐melanocyte stimulating hormone (αMSH) and agouti signaling protein (ASIP), regulate switching between…”
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Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4 by Costin, Gertrude-E, Valencia, Julio C, Vieira, Wilfred D, Lamoreux, M Lynn, Hearing, Vincent J

“…Oculocutaneous albinism (OCA) type 4 is a newly identified human autosomal recessive hypopigmentary disorder that disrupts pigmentation in the skin, hair and…”
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Slc7a11 Gene Controls Production of Pheomelanin Pigment and Proliferation of Cultured Cells by Chintala, Sreenivasulu, Li, Wei, Lamoreux, M. Lynn, Ito, Shosuke, Wakamatsu, Kazumasa, Sviderskaya, Elena V., Bennett, Dorothy C., Park, Young-Mee, Gahl, William A., Huizing, Marjan, Spritz, Richard A., Ben, Songtao, Novak, Edward K., Tan, Jian, Swank, Richard T., Sly, William S.

“…In mammals, > 100 genes regulate pigmentation by means of a wide variety of developmental, cellular, and enzymatic mechanisms. Nevertheless, genes that…”
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The Tyr (albino) locus of the laboratory mouse by Beermann, Friedrich, Orlow, Seth J, Lamoreux, M Lynn

“…The albino mouse was already known in ancient times and was apparently selectively bred in Egypt, China, and Japan. Thus, it is not surprising that the c or…”
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Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein by Costin, Gertrude-E, Valencia, Julio C, Wakamatsu, Kazumasa, Ito, Shosuke, Solano, Francisco, Milac, Adina L, Vieira, Wilfred D, Yamaguchi, Yuji, Rouzaud, François, Petrescu, Andrei-J, Lamoreux, M Lynn, Hearing, Vincent J

“…Dopachrome tautomerase (Dct) is a type I membrane protein and an important regulatory enzyme that plays a pivotal role in the biosynthesis of melanin and in…”
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Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex by Gwynn, Babette, Martina, Jose A., Bonifacino, Juan S., Sviderskaya, Elena V., Lamoreux, M. Lynn, Bennett, Dorothy C., Moriyama, Kengo, Huizing, Marjan, Helip-Wooley, Amanda, Gahl, William A., Webb, Lisa S., Lambert, Amy J., Peters, Luanne L.

“…Hermansky-Pudlak syndrome (HPS), a disorder of organelle biogenesis, affects lysosomes, melanosomes, and platelet dense bodies. Seven genes cause HPS in humans…”
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Genomic, Transcriptional and Mutational Analysis of the Mouse microphthalmia Locus by Hallsson, Jon H, Favor, Jack, Hodgkinson, Colin, Glaser, Tom, Lamoreux, M. Lynn, Magnusdottir, Rannveig, Gunnarsson, Gunnar J, Sweet, Hope O, Copeland, Neal G, Jenkins, Nancy A, Steingrimsson, Eirikur

“…Mouse microphthalmia transcription factor (Mitf) mutations affect the development of four cell types: melanocytes, mast cells, osteoclasts, and pigmented…”
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Interallelic Complementation at the Mouse Mitf Locus by Steingrimsson, Eirikur, Arnheiter, Heinz, Hallsson, Jon Hallsteinn, Lamoreux, M. Lynn, Copeland, Neal G, Jenkins, Nancy A

“…Mutations at the mouse microphthalmia locus (Mitf) affect the development of different cell types, including melanocytes, retinal pigment epithelial cells of…”
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Immortalization of mouse melanocytes carrying mutations in various pigmentation genes by Costin, Gertrude-E., Vieira, Wilfred D., Valencia, Julio C., Rouzaud, François, Lamoreux, M. Lynn, Hearing, Vincent J.

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The Color Loci of Mice - A Genetic Century by Bennett, Dorothy C., Lamoreux, M. Lynn

“…Color loci in mammals are those genetic loci in which mutations can affect pigmentation of the hair, skin, and/or eyes. In the mouse, over 800 phenotypic…”
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Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17 by Theos, Alexander C, Berson, Joanne F, Theos, Sarah C, Herman, Kathryn E, Harper, Dawn C, Tenza, Danièle, Sviderskaya, Elena V, Lamoreux, M Lynn, Bennett, Dorothy C, Raposo, Graça, Marks, Michael S

“…Pmel17 is a pigment cell-specific integral membrane protein that participates in the formation of the intralumenal fibrils upon which melanins are deposited in…”
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Agouti Signaling Protein Inhibits Melanogenesis and the Response of Human Melanocytes to α-Melanotropin by Suzuki, Itaru, Tada, Akihiro, Ollmann, Michael M., Barsh, Gregory S., Im, Sungbin, Lynn Lamoreux, M., Hearing, Vincent J., Nordlund, James J., Abdel-Malek, Zalfa A.

“…In mouse follicular melanocytes, the switch between eumelanin and pheomelanin synthesis is regulated by the extension locus, which encodes the melanocortin-1…”
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Pigment pattern formation in the medaka embryo by Lynn Lamoreux, M., Kelsh, Robert N., Wakamatsu, Yuko, Ozato, Kenjiro

“…Summary For the study of development of pigmentation, compared with mammalian models, fish offer the advantage of multiple chromatophore types and ready access…”
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The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes by Abdel-Malek, Z A, Scott, M C, Furumura, M, Lamoreux, M L, Ollmann, M, Barsh, G S, Hearing, V J

“…The agouti gene codes for agouti signaling protein (ASP), which is temporally expressed in wild-type mouse follicular melanocytes where it induces pheomelanin…”
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Interaction of Major Coat Color Gene Functions in Mice as Studied by Chemical Analysis of Eumelanin and Pheomelanin by LAMOREUX, M. LYNN, WAKAMATSU, KAZUMASA, ITO, SHOSUKE

“…Melanocytes produce two chemically distinct types of melanin pigments, eumelanin and pheomelanin. These pigments can be quantitatively analyzed by acidic…”
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Number of Mast Cells in the Peritoneal Cavity of Mice: Influence of Microphthalmia Transcription Factor through Transcription of Newly Found Mast Cell Adhesion Molecule, Spermatogenic Immunoglobulin Superfamily by Morii, Eiichi, Ito, Akihiko, Jippo, Tomoko, Koma, Yu-ichiro, Oboki, Keisuke, Wakayama, Tomohiko, Iseki, Shoichi, Lamoreux, M. Lynn, Kitamura, Yukihiko

“…The mi (microphthalmia) locus of mice encodes a transcription factor, MITF. B6-tg/tg mice that do not express any MITF have white coats and small eyes…”
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Isolation, Chromosomal Mapping, and Expression of the Mouse Tyrosinase Gene by Kwon, Byoung S., Haq, Asifa K., Wakulchik, Mark, Kestler, Daniel, Barton, David E., Francke, Uta, Lynn Lamoreux, M., Barry Whitney, J., Halaban, Ruth

“…Using a human tyrosinase cDNA probe, we have isolated mouse tyrosinase genomic clones and used them to map the mouse tyrosinase locus and to analyze tile…”
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Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti by Dinulescu, D.M. (Oregon Health Sciences University, Portland, OR.), Fan, W, Boston, B.A, McCall, K, Lamoreux, M.L, Moore, K.J, Montagno, J, Cone, R.D

“…The mahogany (mg) locus originally was identified as a recessive suppressor of agouti, a locus encoding a skin peptide that modifies coat color by antagonizing…”
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Number of Mast Cells in the Peritoneal Cavity of Mice by Morii, Eiichi, Ito, Akihiko, Jippo, Tomoko, Koma, Yu-ichiro, Oboki, Keisuke, Wakayama, Tomohiko, Iseki, Shoichi, Kitamura, Yukihiko, Lamoreux, M. Lynn

“…The mi (microphthalmia) locus of mice encodes a transcription factor, MITF. B6- tg/tg mice that do not express any MITF have white coats and small eyes…”
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