Search Results - "Lamont, Alana"
-
1
Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice
Published in Nature communications (21-02-2024)“…Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron…”
Get full text
Journal Article -
2
Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition
Published in PLoS pathogens (23-12-2020)“…Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women…”
Get full text
Journal Article -
3
Comparative analysis of DNA extraction and PCR product purification methods for cervicovaginal microbiome analysis using cpn60 microbial profiling
Published in PloS one (13-01-2022)“…The microbiota of the lower female genital tract plays an important role in women's health. Microbial profiling using the chaperonin60 (cpn60) universal target…”
Get full text
Journal Article -
4
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
Published in Cell reports (Cambridge) (30-05-2023)“…Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal…”
Get full text
Journal Article -
5
Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus
Published in Microbiome (25-07-2023)“…Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections,…”
Get full text
Journal Article -
6
The neovaginal microbiome of transgender women post-gender reassignment surgery
Published in Microbiome (05-05-2020)“…Gender reassignment surgery is a procedure some transgender women (TW) undergo for gender-affirming purposes. This often includes the construction of a…”
Get full text
Journal Article -
7
Nonoptimal bacteria species induce neutrophil-driven inflammation and barrier disruption in the female genital tract
Published in Mucosal immunology (01-06-2023)“…Neutrophil recruitment and activation within the female genital tract are often associated with tissue inflammation, loss of vaginal epithelial barrier…”
Get full text
Journal Article -
8
The study of host-bacterial relationships and immune function in different vaginal environments (THRIVE Study)
Published in Journal of obstetrics and gynaecology Canada (01-05-2020)“…Bacterial vaginosis (BV) is a common gynecologic complaint, prone to recurrence, with limited therapeutic options. The purpose of this study is to identify…”
Get full text
Journal Article