Search Results - "Lamming, Eleanor D"

An Alternative Cascade for the Selective Methylation of Catechols and Tetrahydroisoquinolines by O‐Methyltransferases by Salinger, Matthew T., Castellano Garrido, Daniel, Lamming, Eleanor D., Ward, John M., Moody, Thomas S., Jeffries, Jack W. E., Hailes, Helen C.

“…Methyltransferases are gaining traction as a method to achieve greener and regioselective methylations of a wide array of substrates. In this work, a halide…”
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‘Dopamine‐first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile by Lichman, Benjamin R, Gershater, Markus C, Lamming, Eleanor D, Pesnot, Thomas, Sula, Altin, Keep, Nicholas H, Hailes, Helen C, Ward, John M

“…Norcoclaurine synthase (NCS) (EC 4.2.1.78) catalyzes the Pictet–Spengler condensation of dopamine and an aldehyde, forming a substituted…”
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Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase by Guzman, Juan D, Pesnot, Thomas, Barrera, Diana A, Davies, Heledd M, McMahon, Eleanor, Evangelopoulos, Dimitrios, Mortazavi, Parisa N, Munshi, Tulika, Maitra, Arundhati, Lamming, Eleanor D, Angell, Richard, Gershater, Markus C, Redmond, Joanna M, Needham, Deborah, Ward, John M, Cuca, Luis E, Hailes, Helen C, Bhakta, Sanjib

“…(S)-Leucoxine, isolated from the Colombian Lauraceae tree Rhodostemonodaphne crenaticupula Madriñan, was found to inhibit the growth of Mycobacterium…”
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C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol by Martin, Liam T., Lamming, Eleanor D., Maitra, Arundhati, Mortazavi, Parisa N., Roddan, Rebecca, Ward, John M., Bhakta, Sanjib, Hailes, Helen C.

“…Introduction The emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease…”
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