Search Results - "Lamkin, Thomas J."
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Hybridization State Detection of DNA-Functionalized Gold Nanoparticles Using Hyperspectral Imaging
Published in International journal of optics (01-01-2017)“…Hyperspectral imaging has the unique ability of capturing spectral data for multiple wavelengths at each pixel in an image. This gives the ability to…”
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Automated analysis and classification of infected macrophages using bright-field amplitude contrast data
Published in Journal of biomolecular screening (01-03-2012)“…This article presents a methodology for acquisition and analysis of bright-field amplitude contrast image data in high-throughput screening (HTS) for the…”
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A Genome-Wide Search for Ionizing-Radiation-Responsive Elements in Deinococcus radiodurans Reveals a Regulatory Role for the DNA Gyrase Subunit A Gene's 5' Untranslated Region in the Radiation and Desiccation Response
Published in Applied and environmental microbiology (15-06-2017)“…Tight regulation of gene expression is important for the survival of , a model bacterium of extreme stress resistance. Few studies have examined the use of…”
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Manganese binding to antioxidant peptides involved in extreme radiation resistance in Deinococcus radiodurans
Published in Journal of inorganic biochemistry (01-11-2016)“…A decapeptide, DEHGTAVMLK (DP1), and its random scrambled version, THMVLAKGED (DP2), have been studied for their interactions with manganese. The amino acid…”
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Mustard gas surrogate, 2-chloroethyl ethylsulfide (2-CEES), induces centrosome amplification and aneuploidy in human and mouse cells: 2-CEES induces centrosome amplification and chromosome instability
Published in Cell biology and toxicology (01-08-2014)“…Mustard gas is a simple molecule with a deadly past. First used as a chemical weapon in World War I, its simple formulation has raised concerns over its use by…”
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Characterization of stable, constitutively expressed, chromosomal green and red fluorescent transcriptional fusions in the select agent bacterium, Francisella tularensis Schu S4 and the surrogate type B live vaccine strain (LVS)
Published in Applied microbiology and biotechnology (01-10-2013)“…Here, we constructed stable, constitutively expressed, chromosomal green (GFP) and red fluorescent (RFP) reporters in the genome of the surrogate strain,…”
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Spiky Gold Nanoshells: Synthesis and Enhanced Scattering Properties
Published in Journal of physical chemistry. C (10-05-2012)“…Gold nanoshells covered with sharp rods called “spiky gold nanoshells” are synthesized by employing a silver-assisted seed-growth method for heterogeneous…”
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RETINOIC ACID, BROMODEOXYURIDINE, AND THE Δ205 MUTANT POLYOMA VIRUS MIDDLE T ANTIGEN REGULATE EXPRESSION LEVELS OF A COMMON ENSEMBLE OF PROTEINS ASSOCIATED WITH EARLY STAGES OF INDUCING HL-60 LEUKEMIC CELL DIFFERENTIATION
Published in In vitro cellular & developmental biology. Animal (01-07-2004)“…Retinoic acid (RA), bromodeoxyuridine (BrdU), and the Δ205 mutant polyoma middle T antigen affect the expression of a common ensemble of proteins in HL-60…”
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High-throughput screening for small-molecule inhibitors of Staphylococcus epidermidis RP62a biofilms
Published in Journal of biomolecular screening (01-08-2013)“…High-throughput screening (HTS) of 42 865 compounds was performed to identify compounds that inhibit formation of or kill Staphylococcus epidermidis RP62a…”
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Rapid targeted gene disruption in Bacillus anthracis
Published in BMC biotechnology (18-09-2013)“…Anthrax is a zoonotic disease recognized to affect herbivores since Biblical times and has the widest range of susceptible host species of any known pathogen…”
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Construction and characterization of stable, constitutively expressed, chromosomal green and red fluorescent transcriptional fusions in the select agents, Bacillus anthracis, Yersinia pestis, Burkholderia mallei, and Burkholderia pseudomallei
Published in MicrobiologyOpen (Weinheim) (01-10-2014)“…Here, we constructed stable, chromosomal, constitutively expressed, green and red fluorescent protein (GFP and RFP) as reporters in the select agents, Bacillus…”
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Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels
Published in Journal of cellular biochemistry (15-04-2006)“…Retinoic acid‐induced expression of the CD38 ectoenzyme receptor in HL‐60 human myeloblastic leukemia cells is regulated by RARα and RXR, and enhanced or…”
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All‐trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL‐60 leukemia cells
Published in American journal of hematology (01-08-2006)“…p62DOK1 (DOK1) and p56DOK2 (DOK2) are sequence homologs that act as docking proteins downstream of receptor or nonreceptor tyrosine kinases. Originally…”
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Retinoic acid induces expression of SLP-76: Expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells
Published in European journal of cell biology (01-02-2006)“…Retinoic acid (RA) is known to cause MAPK signaling which propels G0 arrest and myeloid differentiation of HL-60 human myeloblastic leukemia cells. The present…”
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Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle
Published in Molecular cancer therapeutics (01-05-2002)“…Retinoic acid is known to cause the cell cycle arrest and myeloid differentiation of HL-60 myeloblastic leukemia cells. Evidence suggesting the possible…”
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Cell analytics in compound hit selection of bacterial inhibitors
Published in 2015 IEEE International Conference on Big Data (Big Data) (01-10-2015)“…Identifying novel drugs that inhibit bacterial infection has gained a considerable amount of attention in recent years. This is in part due to the increased…”
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Mapping Infected Cell Phenotype
Published in IEEE transactions on biomedical engineering (2012)Get full text
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Mapping Infected Cell Phenotype
Published in IEEE transactions on biomedical engineering (01-08-2012)“…Quantitative modeling of the phenotypic changes in the host cell during the bacterial infection makes it possible to explore an empirical relation between the…”
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RETINOIC ACID, BROMODEOXYURIDINE, AND THE [Delta]205 MUTANT POLYOMA VIRUS MIDDLE T ANTIGEN REGULATE EXPRESSION LEVELS OF A COMMON ENSEMBLE OF PROTEINS ASSOCIATED WITH EARLY STAGES OF INDUCING HL-60 LEUKEMIC CELL DIFFERENTIATION
Published in In vitro cellular & developmental biology. Animal (01-07-2004)“…Retinoic acid (RA), bromodeoxyuridine (BrdU), and the Delta 205 mutant polyoma middle T antigen affect the expression of a common ensemble of proteins in HL-60…”
Get full text
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Retinoic Acid-induced Growth Arrest and Differentiation: Retinoic Acid Up-Regulates CD32 (FcγRII) Expression, the Ectopic Expression of Which Retards the Cell Cycle 1 Supported in part by grants from the NIH (USPHS) and United States Department of Agriculture. J. W. and T. J. L. are recipients of National Institute of Environmental Health Sciences Training Fellowship ESO7052.1
Published in Molecular cancer therapeutics (01-05-2002)“…Retinoic acid is known to cause the cell cycle arrest and myeloid differentiation of HL-60 myeloblastic leukemia cells. Evidence suggesting the possible…”
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