Search Results - "Lamina, Claudia"

The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis by Cheng, Yurong, Li, Yong, Benkowitz, Paula, Lamina, Claudia, Köttgen, Anna, Sekula, Peggy

“…Blood metabolites of the tryptophan pathway were found to be associated with kidney function and disease in observational studies. In order to evaluate causal…”
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A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study by Duschek, Elena, Forer, Lukas, Schönherr, Sebastian, Gieger, Christian, Peters, Annette, Kronenberg, Florian, Grallert, Harald, Lamina, Claudia

“…The availability of polygenic scores for type 2 diabetes (T2D) raises the question, whether assessing family history might become redundant. However, family…”
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A comprehensive map of single-base polymorphisms in the hypervariable LPA kringle IV type 2 copy number variation region[S] by Coassin, Stefan, Schönherr, Sebastian, Weissensteiner, Hansi, Erhart, Gertraud, Forer, Lukas, Losso, Jamie Lee, Lamina, Claudia, Haun, Margot, Utermann, Gerd, Paulweber, Bernhard, Specht, Günther, Kronenberg, Florian

“…Lipoprotein (a) [Lp(a)] concentrations are among the strongest genetic risk factors for cardiovascular disease and present pronounced interethnic and…”
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Lipoprotein(a) plasma levels are not associated with incident microvascular complications in type 2 diabetes mellitus by Singh, Sunny S., Rashid, Mardin, Lieverse, Aloysius G., Kronenberg, Florian, Lamina, Claudia, Mulder, Monique T., de Rijke, Yolanda B., Sijbrands, Eric J. G., van Hoek, Mandy

“…Aims/hypothesis Microvascular disease in type 2 diabetes is a significant cause of end-stage renal disease, blindness and peripheral neuropathy. The strict…”
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The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat by Grüneis, Rebecca, Weissensteiner, Hansi, Lamina, Claudia, Schönherr, Sebastian, Forer, Lukas, Di Maio, Silvia, Streiter, Gertraud, Peters, Annette, Gieger, Christian, Kronenberg, Florian, Coassin, Stefan

“…Lipoprotein(a) [Lp(a)] concentrations are regulated by the LPA gene mainly via the large kringle IV-type 2 (KIV-2) copy number variation and multiple causal…”
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Lysis reagents, cell numbers, and calculation method influence high-throughput measurement of HDL-mediated cholesterol efflux capacity by Schachtl-Riess, Johanna F., Coassin, Stefan, Lamina, Claudia, Demetz, Egon, Streiter, Gertraud, Hilbe, Richard, Kronenberg, Florian

“…HDL-mediated cholesterol efflux capacity (CEC) may protect against cardiovascular disease. However, CEC assays are not standardized, hampering their…”
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HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study by Hunjadi, Monika, Lamina, Claudia, Kahler, Patrick, Bernscherer, Tamara, Viikari, Jorma, Lehtimäki, Terho, Kähönen, Mika, Hurme, Mikko, Juonala, Markus, Taittonen, Leena, Laitinen, Tomi, Jokinen, Eero, Tossavainen, Päivi, Hutri-Kähönen, Nina, Raitakari, Olli, Ritsch, Andreas

“…The atherogenic process begins already in childhood and progresses to symptomatic condition with age. We investigated the association of cholesterol efflux…”
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Systemic Evidence for Mitochondrial Dysfunction in Age-Related Macular Degeneration as Revealed by mtDNA Copy Number Measurements in Peripheral Blood by Koller, Adriana, Lamina, Claudia, Brandl, Caroline, Zimmermann, Martina E., Stark, Klaus J., Weissensteiner, Hansi, Würzner, Reinhard, Heid, Iris M., Kronenberg, Florian

“…Mitochondrial dysfunction is a common occurrence in the aging process and is observed in diseases such as age-related macular degeneration (AMD). Increased…”
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Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model by Amor, Melina, Diaz, Malena, Bianco, Valentina, Svecla, Monika, Schwarz, Birgit, Rainer, Silvia, Pirchheim, Anita, Schooltink, Laszlo, Mukherjee, Suravi, Grabner, Gernot F, Beretta, Giangiacomo, Lamina, Claudia, Norata, Giuseppe Danilo, Hackl, Hubert, Kratky, Dagmar

“…Activation of brown adipose tissue (BAT) has gained attention due to its ability to dissipate energy and counteract cardiometabolic diseases (CMDs). This study…”
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Nuclear and mitochondrial genetic variants associated with mitochondrial DNA copy number by Koller, Adriana, Filosi, Michele, Weissensteiner, Hansi, Fazzini, Federica, Gorski, Mathias, Pattaro, Cristian, Schönherr, Sebastian, Forer, Lukas, Herold, Janina M., Stark, Klaus J., Döttelmayer, Patricia, Hicks, Andrew A., Pramstaller, Peter P., Würzner, Reinhard, Eckardt, Kai-Uwe, Heid, Iris M., Fuchsberger, Christian, Lamina, Claudia, Kronenberg, Florian

“…Mitochondrial DNA copy number (mtDNA-CN) is a biomarker for mitochondrial dysfunction associated with several diseases. Previous genome-wide association…”
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One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects by Kieback, Arne Georg, Espinola-Klein, Christine, Lamina, Claudia, Moebus, Susanne, Tiller, Daniel, Lorbeer, Roberto, Schulz, Andreas, Meisinger, Christa, Medenwald, Daniel, Erbel, Raimund, Kluttig, Alexander, Wild, Philipp S, Kronenberg, Florian, Kröger, Knut, Ittermann, Till, Dörr, Marcus

“…A meta-analysis using data from seven German population-based cohorts was performed by the German Epidemiological consortium of Peripheral Arterial Disease…”
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A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter by Coassin, Stefan, Hermann-Kleiter, Natascha, Haun, Margot, Wahl, Simone, Wilson, Rory, Paulweber, Bernhard, Kunze, Sonja, Meitinger, Thomas, Strauch, Konstantin, Peters, Annette, Waldenberger, Melanie, Kronenberg, Florian, Lamina, Claudia

“…Lipoprotein(a) [Lp(a)] is a major cardiovascular risk factor, which is largely genetically determined by one major gene locus, the LPA gene. Many aspects of…”
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Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals by Di Maio, Silvia, Grüneis, Rebecca, Streiter, Gertraud, Lamina, Claudia, Maglione, Manuel, Schoenherr, Sebastian, üfner, Dietmar, Thorand, Barbara, Peters, Annette, Eckardt, Kai-Uwe, Köttgen, Anna, Kronenberg, Florian, Coassin, Stefan

“…Abstract Background The concentrations of the highly atherogenic lipoprotein(a) [Lp(a)] are mainly genetically determined by the LPA gene locus. However, up to…”
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Glycated Hemoglobin and Risk of Death in Diabetic Patients Treated With Hemodialysis: A Meta-analysis by Hill, Christopher J., MB, Maxwell, Alexander P., PhD, Cardwell, Christopher R., PhD, Freedman, Barry I., MD, Tonelli, Marcello, MD, Emoto, Masanori, MD, Inaba, Masaaki, MD, Hayashino, Yasuaki, MD, Fukuhara, Shunichi, MD, Okada, Tomonari, MD, Drechsler, Christiane, MD, Wanner, Christoph, MD, Casula, Anna, MS, Adler, Amanda I., PhD, Lamina, Claudia, PhD, Kronenberg, Florian, MD, Streja, Elani, PhD, Kalantar-Zadeh, Kamyar, PhD, Fogarty, Damian G., MD

“…Background Studies investigating the association between glycated hemoglobin (HbA1c ) level and mortality risk in diabetic patients receiving hemodialysis have…”
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Mendelian Randomization: Principles and its usage in Lp(a) research by Lamina, Claudia

“…Epidemiological studies investigating the association between a biomarker and a disease have many limitations. The most prominent among these is that we cannot…”
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Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study by Mack, Salome, Coassin, Stefan, Vaucher, Julien, Kronenberg, Florian, Lamina, Claudia

“…Apolipoprotein A-IV (apoA-IV) has been observed to be associated with lipids, kidney function, adiposity- and diabetes-related parameters. To assess the causal…”
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Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature by Sturm, Gisela, Lamina, Claudia, Zitt, Emanuel, Lhotta, Karl, Haider, Florian, Neyer, Ulrich, Kronenberg, Florian

“…Improved glycemic control reduces complications in patients with diabetes mellitus (DM). However, it is discussed controversially whether patients with…”
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Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population by Coassin, Stefan, Schweiger, Martina, Kloss-Brandstätter, Anita, Lamina, Claudia, Haun, Margot, Erhart, Gertraud, Paulweber, Bernhard, Rahman, Yusof, Olpin, Simon, Wolinski, Heimo, Cornaciu, Irina, Zechner, Rudolf, Zimmermann, Robert, Kronenberg, Florian

“…Recent studies demonstrated a strong influence of rare genetic variants on several lipid-related traits. However, their impact on free fatty acid (FFA) plasma…”
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Genome-Wide Association Analysis of High-Density Lipoprotein Cholesterol in the Population-Based KORA Study Sheds New Light on Intergenic Regions by Heid, Iris M, Boes, Eva, Muller, Martina, Kollerits, Barbara, Lamina, Claudia, Coassin, Stefan, Gieger, Christian, Doring, Angela, Klopp, Norman, Frikke-Schmidt, Ruth, Tybjaerg-Hansen, Anne, Brandstatter, Anita, Luchner, Andreas, Meitinger, Thomas, Wichmann, H.-Erich, Kronenberg, Florian

“…Genome-Wide Association Analysis of High-Density Lipoprotein Cholesterol in the Population-Based KORA Study Sheds New Light on Intergenic Regions Iris M. Heid,…”
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Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data by LAUMEN, Helmut, SANINGONG, Akuma D, KLOPP, Norman, THORAND, Barbara, WICHMANN, H.-Erich, ILLIG, Thomas, HAUNER, Hans, HEID, Iris M, HESS, Jochen, HERDER, Christian, CLAUSSNITZER, Melina, BAUMERT, Jens, LAMINA, Claudia, RATHMANN, Wolfgang, SEDLMEIER, Eva-Maria

“…Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data Helmut Laumen 1 , Akuma D. Saningong 1 , Iris M…”
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