Search Results - "Lamenza, Felipe"
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Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention
Published in Cancer gene therapy (01-08-2023)“…Head and neck squamous cell carcinoma (HNSCC) is a significant public health problem, with a need for novel approaches to chemoprevention and treatment…”
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Modulation of the oral glucocorticoid system during black raspberry mediated oral cancer chemoprevention
Published in Carcinogenesis (New York) (11-02-2022)“…Abstract Recent reports suggest that glucocorticoids (GCs), which can be synthesized in the oral mucosa, play an important role in cancer development…”
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Berries vs. Disease: Revenge of the Phytochemicals
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2024)“…Secondary metabolites and phytochemicals in plant-based diets are known to possess properties that inhibit the development of several diseases including a…”
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Black raspberry extract inhibits regulatory T-cell activity in a murine model of head and neck squamous cell carcinoma chemoprevention
Published in Frontiers in immunology (09-08-2022)“…Head and neck squamous cell carcinomas (HNSCC) are one of the most diagnosed malignancies globally, with a 5-year survival rate of approximately 40% to 50%…”
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Berry Extracts and Their Bioactive Compounds Mitigate LPS and DNFB-Mediated Dendritic Cell Activation and Induction of Antigen Specific T-Cell Effector Responses
Published in Antioxidants (24-08-2023)“…Berries have gained widespread recognition for their abundant natural antioxidant, anti-inflammatory, and immunomodulatory properties. However, there has been…”
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STAT1 is regulated by TRIM24 and promotes immunosuppression in head and neck squamous carcinoma cells, but enhances T cell antitumour immunity in the tumour microenvironment
Published in British journal of cancer (01-09-2022)“…Background Head and neck squamous cell carcinoma (HNSCC) is a significant problem and is frequently resistant to current treatments. STAT1 is important in…”
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Sex differences in susceptibility to substance use disorder: Role for X chromosome inactivation and escape?
Published in Molecular and cellular neuroscience (01-06-2023)“…There is a sex-based disparity associated with substance use disorders (SUDs) as demonstrated by clinical and preclinical studies. Females are known to…”
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Host derived macrophage migration inhibitory factor expression attenuates anti-tumoral immune cell accumulation and promotes immunosuppression in the tumor microenvironment of head and neck squamous cell carcinoma
Published in Biochimica et biophysica acta. Molecular basis of disease (01-10-2024)“…Head and neck squamous cell carcinoma (HNSCC) is a significant public health concern worldwide. Immunomodulatory targets in the HNSCC tumor microenvironment…”
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MicroRNA-21 Deficiency Promotes the Early Th1 Immune Response and Resistance toward Visceral Leishmaniasis
Published in The Journal of immunology (1950) (01-09-2021)“…Abstract MicroRNA-21 (miR-21) inhibits IL-12 expression and impairs the Th1 response necessary for control of Leishmania infection. Recent studies have shown…”
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Ionizing Radiation Reduces Head and Neck Squamous Cell Carcinoma Cell Viability and Is Associated with Predictive Tumor-Specific T Cell Responses
Published in Cancers (25-06-2023)“…Head and neck squamous cell carcinoma (HNSCC) is common and deadly, and there is a need for improved strategies to predict treatment responses. Ionizing…”
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