Search Results - "Lambert, Herman"

HspB8 Chaperone Activity toward Poly(Q)-containing Proteins Depends on Its Association with Bag3, a Stimulator of Macroautophagy by Carra, Serena, Seguin, Samuel J., Lambert, Herman, Landry, Jacques

“…Mutations in HspB8, a member of the B group of heat shock proteins (Hsp), have been associated with human neuromuscular disorders. However, the exact function…”
Get full text

Chaperone-Assisted Mitotic Actin Remodeling by BAG3 and HSPB8 Involves the Deacetylase HDAC6 and Its Substrate Cortactin by Luthold, Carole, Varlet, Alice-Anaïs, Lambert, Herman, Bordeleau, François, Lavoie, Josée N

“…The fidelity of actin dynamics relies on protein quality control, but the underlying molecular mechanisms are poorly defined. During mitosis, the cochaperone…”
Get full text

Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction by Fuchs, Margit, Poirier, Dominic J, Seguin, Samuel J, Lambert, Herman, Carra, Serena, Charette, Steve J, Landry, Jacques

“…The molecular chaperone HspB8 [Hsp (heat-shock protein) B8] is member of the B-group of Hsps. These proteins bind to unfolded or misfolded proteins and protect…”
Get more information

A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis by Fuchs, Margit, Luthold, Carole, Guilbert, Solenn M, Varlet, Alice Anaïs, Lambert, Herman, Jetté, Alexandra, Elowe, Sabine, Landry, Jacques, Lavoie, Josée N

“…The co-chaperone BAG3, in complex with the heat shock protein HSPB8, plays a role in protein quality control during mechanical strain. It is part of a…”
Get full text

Activation of the p38 Signaling Pathway by Heat Shock Involves the Dissociation of Glutathione S-Transferase Mu from Ask1 by Dorion, Sonia, Lambert, Herman, Landry, Jacques

“…Despite the importance of the stress-activated protein kinase pathways in cell death and survival, it is unclear how stressful stimuli lead to their…”
Get full text

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells by Carra, Serena, Sivilotti, Mitchel, Chávez Zobel, Aura T., Lambert, Herman, Landry, Jacques

“…The family of small heat shock proteins (sHsp) is composed of 10 members in mammals, four of which are found mutated in diseases associated with the…”
Get full text

CDK1-Mediated Phosphorylation of BAG3 Promotes Mitotic Cell Shape Remodeling and the Molecular Assembly of Mitotic p62 Bodies by Luthold, Carole, Lambert, Herman, Guilbert, Solenn M, Rodrigue, Marc-Antoine, Fuchs, Margit, Varlet, Alice-Anaïs, Fradet-Turcotte, Amélie, Lavoie, Josée N

“…The cochaperone BCL2-associated athanogene 3 (BAG3), in complex with the heat shock protein HSPB8, facilitates mitotic rounding, spindle orientation, and…”
Get full text

Inhibition of Daxx-Mediated Apoptosis by Heat Shock Protein 27 by Charette, Steve J., Lavoie, Josée N., Lambert, Herman, Landry, Jacques

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27 by Guay, J, Lambert, H, Gingras-Breton, G, Lavoie, J N, Huot, J, Landry, J

“…We have studied the contribution of the individual kinases of the MAP (mitogen-activated protein) kinase family, including ERK (extracellular-signal regulated…”
Get full text

HSP27 Multimerization Mediated by Phosphorylation-sensitive Intermolecular Interactions at the Amino Terminus by Lambert, H, Charette, S J, Bernier, A F, Guimond, A, Landry, J

“…Distinct biochemical activities have been reported for small and large molecular complexes of heat shock protein 27 (HSP27), respectively. Using glycerol…”
Get full text

Essential Role of the NH2-terminal WD/EPF Motif in the Phosphorylation-activated Protective Function of Mammalian Hsp27 by Thériault, Jimmy R., Lambert, Herman, Chávez-Zobel, Aura T., Charest, Gabriel, Lavigne, Pierre, Landry, Jacques

“…Hsp27 is expressed at high levels after mild heat shock and contributes to making cells extremely resistant to subsequent treatments. The activity of the…”
Get full text

Hidden diversity uncovered in Hygrophorus sect. Aurei (Hygrophoraceae), including the Mediterranean H. meridionalis and the North American H. boyeri, spp. nov by Pierre-Arthur, Moreau, Jean-Michel, Bellanger, Renée, Lebeuf, Zacharias, Athanassiou, Antonis, Athanasiades, Herman, Lambert, Christian, Schwarz, Ellen, Larsson, Michael, Loizides

“…For many years, the binomial Hygrophorus hypothejus was widely applied to collections from various geographical regions in different continents, assuming a…”
Get full text

Validation of two Amanita species from eastern North America: A. rhacopus sp. nov. and A. variicolor sp. nov by Lambert, Herman, Fortin, Guy, Labbé, Roland, Labrecque, Jacqueline, Bérubé, Jean A., Landry, Jacques, Ilyukhin, Evgeny, Margaritescu, Simona, Moncalvo, Jean-Marc, Lamoureux, Yves

“…Members of the mushroom genus Amanita usually can easily be identified to the genus in the field, however, species circumscription and identification are often…”
Get full text

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27 by Lavoie, Josée N., Lambert, Herman, Hickey, Eileen, Weber, Lee A., Landry, Jacques

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A Kinase-independent Function of Ask1 in Caspase-independent Cell Death by Charette, Steve J., Lambert, Herman, Landry, Jacques

“…Ask1 (apoptosissignal-regulating kinase 1) is activated as a consequence of cell exposure to a variety of stresses and can then initiate apoptosis. A known…”
Get full text

Phosphorylation of HSP27 during development and decay of thermotolerance in Chinese hamster cells by Landry, J, Chrétien, P, Laszlo, A, Lambert, H

“…The small molecular weight heat shock protein HSP27 was recently shown to confer a stable thermoresistant phenotype when expressed constitutively in mammalian…”
Get more information

HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency by Guilbert, Solenn M., Lambert, Herman, Rodrigue, Marc‐Antoine, Fuchs, Margit, Landry, Jacques, Lavoie, Josée N.

“…BCL2‐associated athanogene (BAG)‐3 is viewed as a platform that would physically and functionally link distinct classes of molecular chaperones of the heat…”
Get full text

HspB8 Participates in Protein Quality Control by a Non-chaperone-like Mechanism That Requires eIF2α Phosphorylation by Carra, Serena, Brunsting, Jeanette F., Lambert, Herman, Landry, Jacques, Kampinga, Harm H.

“…Aggregation of mutated proteins is a hallmark of many neurodegenerative disorders, including Huntington disease. We previously reported that overexpression of…”
Get full text

Fine-tuning of actin dynamics by the HSPB8-BAG3 chaperone complex facilitates cytokinesis and contributes to its impact on cell division by Varlet, Alice Anaïs, Fuchs, Margit, Luthold, Carole, Lambert, Herman, Landry, Jacques, Lavoie, Josée N.

“…The small heat shock protein HSPB8 and its co-chaperone BAG3 are proposed to regulate cytoskeletal proteostasis in response to mechanical signaling in muscle…”
Get full text

Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death by Dziengelewski, Claire, Rodrigue, Marc-Antoine, Caillier, Alexia, Jacquet, Kévin, Boulanger, Marie-Chloé, Bergeman, Jonathan, Fuchs, Margit, Lambert, Herman, Laprise, Patrick, Richard, Darren E, Bordeleau, François, Huot, Marc-Étienne, Lavoie, Josée N

“…The tumor cell-selective killing activity of the adenovirus type 2 early region 4 ORF4 (E4orf4) protein is poorly defined at the molecular level. Here, we show…”
Get full text