Search Results - "Lambert, Ben"
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What does the COVID-19 pandemic mean for HIV, tuberculosis, and malaria control?
Published in Tropical medicine and health (13-05-2020)“…Despite its current relatively low global share of cases and deaths in Africa compared to other regions, coronavirus disease 2019 (COVID-19) has the potential…”
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The perpendicular Neumann problem for mean curvature flow with a timelike cone boundary condition
Published in Transactions of the American Mathematical Society (01-07-2014)“…This paper demonstrates existence for all time of mean curvature flow in Minkowski space with a perpendicular Neumann boundary condition, where the boundary…”
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Angular reproduction numbers improve estimates of transmissibility when disease generation times are misspecified or time-varying
Published in Proceedings of the Royal Society. B, Biological sciences (27-09-2023)“…We introduce the , which measures time-varying changes in epidemic transmissibility resulting from variations in both the effective reproduction number , and…”
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Estimating the extrinsic incubation period of malaria using a mechanistic model of sporogony
Published in PLoS computational biology (01-02-2021)“…During sporogony, malaria-causing parasites infect a mosquito, reproduce and migrate to the mosquito salivary glands where they can be transmitted the next…”
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Using patient biomarker time series to determine mortality risk in hospitalised COVID-19 patients: A comparative analysis across two New York hospitals
Published in PloS one (18-08-2022)“…A large range of prognostic models for determining the risk of COVID-19 patient mortality exist, but these typically restrict the set of biomarkers considered…”
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A geometric inequality for convex free boundary hypersurfaces in the unit ball
Published in Proceedings of the American Mathematical Society (01-09-2017)“…We use the inverse mean curvature flow with a free boundary perpendicular to the sphere to prove a geometric inequality involving the Willmore energy for…”
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A review of prospective pathways and impacts of COVID-19 on the accessibility, safety, quality, and affordability of essential medicines and vaccines for universal health coverage in Africa
Published in Globalization and health (08-04-2021)“…The ongoing pandemic of coronavirus disease 2019 (COVID-19) has the potential to reverse progress towards global targets. This study examines the risks that…”
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Context-specific emergence and growth of the SARS-CoV-2 Delta variant
Published in Nature (London) (06-10-2022)“…The SARS-CoV-2 Delta (Pango lineage B.1.617.2) variant of concern spread globally, causing resurgences of COVID-19 worldwide 1 , 2 . The emergence of the Delta…”
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Spacelike Mean Curvature Flow
Published in The Journal of geometric analysis (01-02-2021)“…We prove long-time existence and convergence results for spacelike solutions to mean curvature flow in the pseudo-Euclidean space R n , m , which are entire or…”
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Simulating clinical trials for model-informed precision dosing: using warfarin treatment as a use case
Published in Frontiers in pharmacology (19-10-2023)“…Treatment response variability across patients is a common phenomenon in clinical practice. For many drugs this inter-individual variability does not require…”
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Filter inference: A scalable nonlinear mixed effects inference approach for snapshot time series data
Published in PLoS computational biology (01-05-2023)“…Variability is an intrinsic property of biological systems and is often at the heart of their complex behaviour. Examples range from cell-to-cell variability…”
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Estimating the effects of temperature on transmission of the human malaria parasite, Plasmodium falciparum
Published in Nature communications (22-04-2024)“…Despite concern that climate change could increase the human risk to malaria in certain areas, the temperature dependency of malaria transmission is poorly…”
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Investigating the dose-dependency of the midgut escape barrier using a mechanistic model of within-mosquito dengue virus population dynamics
Published in PLoS pathogens (01-04-2024)“…Arboviruses can emerge rapidly and cause explosive epidemics of severe disease. Some of the most epidemiologically important arboviruses, including dengue…”
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Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in Africa: a systematic analysis of national trends
Published in BMJ global health (01-11-2020)“…IntroductionThe rising burden of drug resistance is a major challenge to the global fight against malaria. We estimated national Plasmodium falciparum…”
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Birds invest wingbeats to keep a steady head and reap the ultimate benefits of flying together
Published in PLoS biology (18-06-2019)“…Flapping flight is the most energetically demanding form of sustained forwards locomotion that vertebrates perform. Flock dynamics therefore have significant…”
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Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data
Published in eLife (09-06-2023)“…The factors leading to the global emergence of Enterovirus D68 (EV-D68) in 2014 as a cause of acute flaccid myelitis (AFM) in children are unknown. To…”
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The use of driving endonuclease genes to suppress mosquito vectors of malaria in temporally variable environments
Published in Malaria journal (04-04-2018)“…The use of gene drive systems to manipulate populations of malaria vectors is currently being investigated as a method of malaria control. One potential system…”
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Health inequities and clustering of fever, acute respiratory infection, diarrhoea and wasting in children under five in low- and middle-income countries: a Demographic and Health Surveys analysis
Published in BMC medicine (24-06-2021)“…Pneumonia, diarrhoea and malaria are responsible for over one third of all deaths in children under the age of 5 years in low and middle sociodemographic index…”
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Neutral syndrome
Published in Nature human behaviour (01-08-2020)“…Neutral models of evolution assume the absence of natural selection. Formerly confined to ecology and evolutionary biology, neutral models are spreading. In…”
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Endemic and Epidemic Human Alphavirus Infections in Eastern Panama: An Analysis of Population-Based Cross-Sectional Surveys
Published in The American journal of tropical medicine and hygiene (01-12-2020)“…Madariaga virus (MADV) has recently been associated with severe human disease in Panama, where the closely related Venezuelan equine encephalitis virus (VEEV)…”
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