Search Results - "Lamb, J D"

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation by Pairet, N, Mang, S, Fois, G, Keck, M, Kühnbach, M, Gindele, J, Frick, M, Dietl, P, Lamb, D J

“…Mechanical ventilation is an important tool for supporting critically ill patients but may also exert pathological forces on lung cells leading to…”
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Determinants of serum copper, zinc and selenium in healthy subjects by Ghayour-Mobarhan, M, Taylor, A, New, S A, Lamb, D J, Ferns, G A A

“…We have investigated the association between serum copper, zinc and selenium concentrations, dietary intake, and demographic characteristics, including…”
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An SNP in protamine 1: a possible genetic cause of male infertility? by Iguchi, N, Yang, S, Lamb, D J, Hecht, N B

“…Gene targeting of the sperm nuclear proteins, the protamines, in mice leads to haploinsufficiency, abnormal chromatin compaction, sperm DNA damage, and male…”
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Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25 by Taylor, E B, Ellingson, W J, Lamb, J D, Chesser, D G, Winder, W W

“…Activation of the AMP-activated protein kinase (AMPK) results in acute changes in cellular metabolism and transcriptional events that make the cell more robust…”
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Androgen receptor mutations in prostate cancer by MARCELLI, M, ITTMANN, M, EASTHAM, J, WEIGEL, N. L, LAMB, D. J, MARIANI, S, SUTHERLAND, R, NIGAM, R, MURTHY, L, YALI ZHAO, DICONCINI, D, PUXEDDU, E, ESEN, A

“…We analyzed the frequency and relevance of mutations in the coding region of the androgen receptor (AR) in genomic DNA extracted from 137 specimens of prostate…”
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THE GENETICS OF MALE INFERTILITY: A FIELD OF STUDY WHOSE TIME IS NOW by Carrell, D. T., De Jonge, C., Lamb, D. J.

“…Idiopathic male infertility is often associated with genetic and epigenetic abnormalities. Such abnormalities include chromosome translocations and…”
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Enzyme-based determination of cholesterol using the quartz crystal acoustic wave sensor by Martin, S.P, Lamb, D.J, Lynch, J.M, Reddy, S.M

“…We have used the AT-cut quartz crystal sensor to measure in real-time the total cholesterol concentration in buffer and serum, using the trienzyme system of…”
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Association between indices of body mass and antibody titres to heat-shock protein-60, -65 and -70 in healthy Caucasians by Ghayour-Mobarhan, M, Taylor, A, Lamb, D.J, Ferns, G.A.A

“…We have previously shown that antibody titres to several heat-shock proteins (Hsps) are elevated in dyslipidaemic patients and subjects with established…”
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Endurance training increases LKB1 and MO25 protein but not AMP-activated protein kinase kinase activity in skeletal muscle by Taylor, E B, Hurst, D, Greenwood, L J, Lamb, J D, Cline, T D, Sudweeks, S N, Winder, W W

“…LKB1 complexed with MO25 and STRAD has been identified as an AMP-activated protein kinase kinase (AMPKK). We measured relative LKB1 protein abundance and AMPKK…”
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Correlation between simultaneous PSA and serum testosterone concentrations among eugonadal, untreated hypogonadal and hypogonadal men receiving testosterone replacement therapy by Grober, E D, Lamb, D J, Khera, M, Murthy, L, Lipshultz, L I

“…The primary objective of this study was to correlate simultaneous measures of prostate-specific antigen (PSA) and serum testosterone among large samples of…”
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Microsatellite instability and defects in mismatch repair proteins: a new aetiology for Sertoli cell‐only syndrome by Maduro, M.R., Casella, R., Kim, E., Lévy, N., Niederberger, C., Lipshultz, L.I., Lamb, D.J.

“…Microsatellite instability is characteristic of certain types of cancer, and is present in rodents lacking specific DNA mismatch repair proteins. These…”
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FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferation by Ropiquet, F, Giri, D, Lamb, D J, Ittmann, M

“…To determine if overexpression of FGF7 and FGF2 occurs in benign prostatic hyperplasia (BPH) and if so, whether such overexpression is correlated with…”
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Heat Shock Protein Antibody Titers Are Reduced by Statin Therapy in Dyslipidemic Subjects: A Pilot Study by Ghayour-Mobarhan, M., Lamb, D. J., Vaidya, N., Livingstone, C., Wang, T., Ferns, G. A. A.

“…Antibody titers to heat shock protein (Hsp)-60 and -65 are positively related to risk of vascular disease and cardiovascular endpoints. There are few data on…”
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Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2‐induced airway inflammation and remodeling by Tabeling, C., Herbert, J., Hocke, A. C., Lamb, D. J., Wollin, S. L., Erb, K. J., Boiarina, E., Movassagh, H., Scheffel, J., Doehn, J. M., Hippenstiel, S., Maurer, M., Gounni, A. S., Kuebler, W. M., Suttorp, N., Witzenrath, M.

“…Background Spleen tyrosine kinase (Syk) is an intracellular nonreceptor tyrosine kinase, which has been implicated as central immune modulator promoting…”
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Semen quality, infertility and mortality in the USA by Eisenberg, M. L., Li, S., Behr, B., Cullen, M. R., Galusha, D., Lamb, D. J., Lipshultz, L. I.

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The possible role of copper ions in atherogenesis: the Blue Janus by Ferns, Gordon A.A, Lamb, David J, Taylor, Andrew

“…It has been proposed that the oxidative modification of low density lipoprotein (LDL) is a key event in human atherogenesis. Copper ions can catalyse the…”
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Palatal discrepancies and postdams by LAMB, D. J., SAMARA, R., JOHNSON, A.

“…summary  To investigate the variation in post‐cure palatal discrepancy of dentures, 20 complete maxillary replica dentures were prepared on models with high…”
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Characterization of the putative cholesterol transport protein metastatic lymph node 64 in the brain by King, S.R., Smith, A.G.A., Alpy, F., Tomasetto, C., Ginsberg, S.D., Lamb, D.J.

“…Intracellular management of cholesterol is a critical process in the brain. Deficits with cholesterol transport and storage are linked to neurodegenerative…”
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Testosterone therapy and mortality risk by Eisenberg, M L, Li, S, Herder, D, Lamb, D J, Lipshultz, L I

“…Recent data suggest an increased risk of cardiovascular events and mortality in men on testosterone therapy (TT). To date, there are no long-term, prospective…”
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Genetic effects of intracytoplasmic sperm injection by Simpson, J L, Lamb, D J

“…Intracytoplasmic sperm injection (ICSI) must be proved safe as well as efficacious. In this communication we first review available data following ICSI…”
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