Search Results - "Lamb, Derek R"

Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma by Setua, Saini, Thangaraju, Kiruphagaran, Dzieciatkowska, Monika, Wilkerson, Rebecca B., Nemkov, Travis, Lamb, Derek R., Tagaya, Yutaka, Boyer, Tori, Rowden, Tobi, Doctor, Allan, D’Alessandro, Angelo, Buehler, Paul W.

“…Extracellular vesicles (EVs) participate in cell-to-cell communication and contribute toward homeostasis under physiological conditions. But EVs can also…”
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Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease by Thangaraju, Kiruphagaran, Setua, Saini, Lisk, Christina, Swindle, Delaney, Stephenson, Daniel, Dzieciatkowska, Monika, Lamb, Derek R., Moitra, Parikshit, Pak, David, Hassell, Kathryn, George, Gemlyn, Nuss, Rachelle, Davizon-Castillo, Pavel, Stenmark, Kurt R., D’Alessandro, Angelo, Irwin, David C., Buehler, Paul W.

“…Aberrant coagulation in sickle cell disease (SCD) is linked to extracellular vesicle (EV) exposure. However, there is no consensus on the contributions of…”
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Biophysical Analysis and Preclinical Pharmacokinetics–Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute by Greenfield, Alisyn, Lamb, Derek R., Gu, Xiangming, Thangaraju, Kiruphagaran, Setua, Saini, Yahya, Ahmad, Vahedi, Amid, Khan, Mohd. Asim, Wang, Qihong, Buehler, Paul W., Palmer, Andre F.

“…Red blood cell (RBC) substitutes tested in late-phase clinical trials contained low-molecular-weight hemoglobin species (<500 kDa), resulting in…”
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The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation by Lamb, Derek R., Greenfield, Alisyn, Thangaraju, Kiruphagaran, Setua, Saini, Eiker, Gena, Wang, Qihong, Vahedi, Amid, Khan, Mohd. Asim, Yahya, Ahmad, Cabrales, Pedro, Palmer, Andre F., Buehler, Paul W.

“…Polymerized human hemoglobin (PolyhHb) has shown promise in preclinical hemorrhagic shock settings. Different synthetic and purification schemes can control…”
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Primaquine-5,6-Orthoquinone Is Directly Hemolytic to Older G6PD Deficient RBCs in a Humanized Mouse Model by Dziewulska-Cronk, Karolina H, Reisz, Julie A, Hay, Ariel M, Nemkov, Travis, Cendali, Francesca I, Issaian, Aaron, Lamb, Derek R, Palha, Mitasha S, Legenzov, Eric A, Kao, Joseph P Y, Walker, Larry A, Tekwani, Babu L, Buehler, Paul W, D'Alessandro, Angelo, Zimring, James C

“…Primaquine and Tafenoquine are the only approved drugs that can achieve a radical cure for malaria but are contraindicated in patients who are deficient in…”
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Superoxide measurement as a novel probe of red blood cell storage quality by Palha, Mitasha S., Legenzov, Eric A., Lamb, Derek R., Zimring, James C., Buehler, Paul W., Kao, Joseph P. Y.

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