Search Results - "Lamb, A."

Measurements of Solar Differential Rotation and Meridional Circulation from Tracking of Photospheric Magnetic Features by Lamb, Derek A

“…Long-lived rotational and meridional flows are important ingredients of the solar cycle. Magnetic field images have typically been used to measure these flows…”
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The autophagosome: origins unknown, biogenesis complex by Lamb, Christopher A., Yoshimori, Tamotsu, Tooze, Sharon A.

“…Key Points Autophagy is an evolutionarily conserved lysosome-mediated degradation process that involves membrane-bound organelles called autophagosomes…”
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Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models by Rajput, P.S, Lyden, P.D, Chen, B, Lamb, J.A, Pereira, B, Lamb, A, Zhao, L, Lei, I.-F, Bai, J

“…Highlights • PAR-1 knockdown neuronal and astrocytes cells are negative for TUNEL-positive cells. • PAR-1 knockdown results in 70% reduction of dying neurons…”
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Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation by Abdella, Ryan, Aggarwal, Megha, Okura, Takashi, Lamb, Robert A., He, Yuan

“…Paramyxoviruses are enveloped, nonsegmented, negative-strand RNA viruses that cause a wide spectrum of human and animal diseases. The viral genome, packaged by…”
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Risk factors and disease mechanisms in myositis by Miller, Frederick W., Lamb, Janine A., Schmidt, Jens, Nagaraju, Kanneboyina

“…Key Points Multiple independent associations within the HLA 8.1 ancestral haplotype are the strongest genetic risk factors for idiopathic inflammatory…”
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The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly by Bruns, Annie M., Leser, George P., Lamb, Robert A., Horvath, Curt M.

“…Cytoplasmic pattern recognition receptors detect non-self RNAs during virus infections and initiate antiviral signaling. One receptor, MDA5, possesses…”
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The Structure, Function, and Pathobiology of the Influenza A and B Virus Ion Channels by Lamb, Robert A

“…Influenza A virus AM2 protein is an integral membrane protein that is an ion channel (also known as a viroporin). The channel has 24 extracellular residues, 19…”
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The Genetics of Autoimmune Myositis by Lamb, Janine A

“…The idiopathic inflammatory myopathies (IIM) are rare, heterogeneous systemic autoimmune disorders, characterized by inflammation of skeletal muscle and…”
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Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease by de Lange, Katrina M, Moutsianas, Loukas, Lee, James C, Lamb, Christopher A, Luo, Yang, Kennedy, Nicholas A, Jostins, Luke, Rice, Daniel L, Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R, Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C, Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G, Newman, William G, Parkes, Miles, Lees, Charlie W, Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J, Ahmad, Tariq, Mansfield, John C, Anderson, Carl A, Barrett, Jeffrey C

“…Jeffrey Barrett, Carl Anderson and colleagues report the results of a large genome-wide association study of inflammatory bowel disease. They identify 25 new…”
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Influenza A virus uses intercellular connections to spread to neighboring cells by Roberts, Kari L, Manicassamy, Balaji, Lamb, Robert A

“…In the extracellular environment, cell-free virions seek out naive host cells over long distances and between organisms. This is the primary mechanism of…”
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Lateral Organization of Influenza Virus Proteins in the Budozone Region of the Plasma Membrane by Leser, George P, Lamb, Robert A

“…Influenza virus assembles and buds at the plasma membrane of virus-infected cells. The viral proteins assemble at the same site on the plasma membrane for…”
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Endocytosis and autophagy: Shared machinery for degradation by Lamb, Christopher A., Dooley, Hannah C., Tooze, Sharon A.

“…Two key questions in the autophagy field are the mechanisms that underlie the signals for autophagy initiation and the source of membrane for expansion of the…”
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Highly efficient methane biocatalysis revealed in a methanotrophic bacterium by Kalyuzhnaya, M. G., Yang, S., Rozova, O. N., Smalley, N. E., Clubb, J., Lamb, A., Gowda, G. A. Nagana, Raftery, D., Fu, Y., Bringel, F., Vuilleumier, S., Beck, D. A. C., Trotsenko, Y. A., Khmelenina, V. N., Lidstrom, M. E.

“…Methane is an essential component of the global carbon cycle and one of the most powerful greenhouse gases, yet it is also a promising alternative source of…”
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British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic by Kennedy, Nicholas A, Jones, Gareth-Rhys, Lamb, Christopher A, Appleby, Richard, Arnott, Ian, Beattie, R Mark, Bloom, Stuart, Brooks, Alenka J, Cooney, Rachel, Dart, Robin J, Edwards, Cathryn, Fraser, Aileen, Gaya, Daniel R, Ghosh, Subrata, Greveson, Kay, Hansen, Richard, Hart, Ailsa, Hawthorne, A Barney, Hayee, Bu'Hussain, Limdi, Jimmy K, Murray, Charles D, Parkes, Gareth C, Parkes, Miles, Patel, Kamal, Pollok, Richard C, Powell, Nick, Probert, Chris S, Raine, Tim, Sebastian, Shaji, Selinger, Christian, Smith, Philip J, Stansfield, Catherine, Younge, Lisa, Lindsay, James O, Irving, Peter M, Lees, Charlie W

“…The COVID-19 pandemic is putting unprecedented pressures on healthcare systems globally. Early insights have been made possible by rapid sharing of data from…”
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TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic by Lamb, Christopher A, Nühlen, Stefanie, Judith, Delphine, Frith, David, Snijders, Ambrosius P, Behrends, Christian, Tooze, Sharon A

“…Macroautophagy requires membrane trafficking and remodelling to form the autophagosome and deliver its contents to lysosomes for degradation. We have…”
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TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes by Longatti, Andrea, Lamb, Christopher A, Razi, Minoo, Yoshimura, Shin-ichiro, Barr, Francis A, Tooze, Sharon A

“…Autophagy is a bulk degradation process characterized by the formation of double membrane vesicles called autophagosomes. The exact molecular mechanism of…”
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Maternal breastmilk, infant gut microbiome and the impact on preterm infant health by Granger, Claire L., Embleton, Nicholas D., Palmer, Jeremy M., Lamb, Christopher A., Berrington, Janet E., Stewart, Christopher J.

“…Aim This narrative review summarises the benefits of maternal breastmilk to both the infant and the mother, specifically the benefits that relate to…”
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Progesterone receptors in normal breast development and breast cancer by Giulianelli, Sebastian, Lamb, Caroline A, Lanari, Claudia

“…Progesterone receptors (PR) play a pivotal role in many female reproductive tissues such as the uterus, the ovary, and the mammary gland (MG). Moreover, PR…”
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Filamentous Influenza Virus Enters Cells via Macropinocytosis by ROSSMAN, Jeremy S, LESER, George P, LAMB, Robert A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activation of paramyxovirus membrane fusion and virus entry by Jardetzky, Theodore S, Lamb, Robert A

“…•Most paramyxoviruses require attachment and fusion (F) proteins for cell entry.•Competing ‘clamp’ and ‘provocateur’ models have been proposed as entry…”
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