Search Results - "Lamani, Manjunath"

NIS-Catalyzed Reactions: Amidation of Acetophenones and Oxidative Amination of Propiophenones by Lamani, Manjunath, Prabhu, Kandikere Ramaiah

“…Single‐step amination: The N‐iodosuccinimide (NIS)‐catalyzed amidation of acetophenone derivatives by using tert‐butylhydroperoxide (TBHP) as an oxidant is…”
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Iodine-Catalyzed Amination of Benzoxazoles: A Metal-Free Route to 2-Aminobenzoxazoles under Mild Conditions by Lamani, Manjunath, Prabhu, Kandikere Ramaiah

“…A facile metal-free route of oxidative amination of benzoxazole by activation of C–H bonds with secondary or primary amines in the presence of catalytic iodine…”
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A Transition Metal-Free Minisci Reaction: Acylation of Isoquinolines, Quinolines, and Quinoxaline by Siddaraju, Yogesh, Lamani, Manjunath, Prabhu, Kandikere Ramaiah

“…Transition metal-free acylation of isoquinoline, quinoline, and quinoxaline derivatives has been developed employing a cross dehydrogenative coupling (CDC)…”
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A Versatile C–H Functionalization of Tetrahydroisoquinolines Catalyzed by Iodine at Aerobic Conditions by Dhineshkumar, Jayaraman, Lamani, Manjunath, Alagiri, Kaliyamoorthy, Prabhu, Kandikere Ramaiah

“…A versatile aerobic catalytic system (I2 and O2/TBHP) for C–H functionalization is reported. This CDC (cross-dehydrogentive coupling) reaction is compatible…”
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Efficient Oxidation of Primary Azides Catalyzed by Copper Iodide: A Convenient Method for the Synthesis of Nitriles by Lamani, Manjunath, Prabhu, Kandikere Ramaiah

“…A wide range of primary azides have been efficiently oxidized by a catalytic amount of CuI and TBHP into their corresponding nitriles in aqueous solution. A…”
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Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors by Malamas, Michael S, Lamani, Manjunath, Farah, Shrouq I, Mohammad, Khadijah A, Miyabe, Christina Yume, Rajarshi, Girija, Wu, Simiao, Zvonok, Nikolai, Chandrashekhar, Honrao, Wood, JodiAnne, Makriyannis, Alexandros

“…Fine-tuning than complete disruption of 2-arachidonoylglycerol (2-AG) metabolism in the brain represents a promising pharmacological approach to limit…”
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Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors by Malamas, Michael S., Farah, Shrouq I., Lamani, Manjunath, Pelekoudas, Dimitrios N., Perry, Nicholas Thomas, Rajarshi, Girija, Miyabe, Christina Yume, Chandrashekhar, Honrao, West, Jay, Pavlopoulos, Spiro, Makriyannis, Alexandros

“…[Display omitted] N-acylethanolamine acid amidase (NAAA) inhibition represents an exciting novel approach to treat inflammation and pain. NAAA is a cysteine…”
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Total Synthesis of Myceliothermophins C, D, and E by Nicolaou, K. C., Shi, Lei, Lu, Min, Pattanayak, Manas R., Shah, Akshay A., Ioannidou, Heraklidia A., Lamani, Manjunath

“…The total synthesis of cytotoxic polyketides myceliothermophins E (1), C (2), and D (3) through a cascade‐based cyclization to form the trans‐fused decalin…”
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Autism Spectrum Disorder: Automated Detection based on rs-fMRI images using CNN by Lamani, Manjunath Ramanna, Julian Benadit, P, Vaithinathan, Krishnakumar

“…Autism spectrum disorder (ASD) impacts approximately 1 in every 160 children globally and is classified as a neurodevelopmental condition. Image classification…”
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Energy efficient heterogeneous clustering scheme using improved golden eagle optimization algorithm for WSN-based IoT by Silambarasan, E., Naresh, E., Asha, V., Lamani, Manjunath Ramanna

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Total Synthesis of Thailanstatin A by Nicolaou, K. C, Rhoades, Derek, Lamani, Manjunath, Pattanayak, Manas R, Kumar, S. Mothish

“…The total synthesis of the spliceosome inhibitor thailanstatin A has been achieved in a longest linear sequence of nine steps from readily available starting…”
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Efficient feature fusion model withmodified bidirectional LSTM for automatic Parkinson's disease classification by Reshma, S, Chennakesavulu, M., Patil, Shweta Sidagounda, Lamani, Manjunath Ramanna

“…The majority of people affected by Parkinson’s disease (PD) are middle-aged and older. The condition causes a variety of severe symptoms, including tremors,…”
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The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity by Kokona, Despina, Spyridakos, Dimitris, Tzatzarakis, Manolis, Papadogkonaki, Sofia, Filidou, Eirini, Arvanitidis, Konstantinos I., Kolios, George, Lamani, Manjunath, Makriyannis, Alexandros, Malamas, Michael S., Thermos, Kyriaki

“…The endocannabinoid system has been shown to be a putative therapeutic target for retinal disease. Here, we aimed to investigate the ability of the…”
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Correction to Iodine-Catalyzed Amination of Benzoxazoles: A Metal-Free Route to 2-Aminobenzoxazoles under Mild Conditions by Lamani, Manjunath, Prabhu, Kandikere Ramaiah

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WITHDRAWN: Design and synthesis of highly potent dual ABHD6/MGL inhibitors by Malamas, Michael S., Lamani, Manjunath, Farah, Shrouq I., Mohammad, Khadijah A., Miyabe, Christina Yume, Weerts, Catherine M., Speziale, Michael, Hilston, Samantha, Zvonok, Nikolai, Chandrashekhar, Honrao, Ploss, Maya, Straiker, Alex, Makriyannis, Alexandros

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Abstract P253: Potent and selective AXL tyrosine kinase inhibition demonstrates significant anti-tumor efficacy in combination with standard of care therapeutics in preclinical models by Paprcka, Susan L., Sridhar, Subhasree, Luu, Irene M., Jafri, Salema, Miles, Dillon H., Liu, Suan, Flores, Ruben, Qu, Shiwei, Lamani, Manjunath, Paladugu, Sriivas, Meleza, Cesar, Wu, James, Singh, Hema, Chen, Yu, Cho, Sean, Udyavar, Akshata, Kaplan, Angelo, Stargnaro, Enzo, Zhao, Xiaoning, Jin, Lixia, Leleti, Manmohan R., Young, Stephen W., Powers, Jay P., Walters, Matthew J., Fernandez-Salas, Ester

“…Background. AXL receptor tyrosine kinase (AXL) is a transmembrane protein that is overexpressed in a variety of tumors and correlates with poor prognosis in…”
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Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology by Lamani, Manjunath, Malamas, Michael S., Farah, Shrouq I., Shukla, Vidyanand G., Almeida, Michael F., Weerts, Catherine M., Anderson, Joseph, Wood, JodiAnne T., Farizatto, Karen L.G., Bahr, Ben A., Makriyannis, Alexandros

“…[Display omitted] FAAH inhibitors offer safety advantages by augmenting the anandamide levels “on demand” to promote neuroprotective mechanisms without the…”
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Iron(III) Chloride-Catalysed Aerobic Reduction of Olefins using Aqueous Hydrazine at Ambient Temperature by Lamani, Manjunath, Ravikumara, Guralamata S., Prabhu, Kandikere Ramaiah

“…A chemoselective reduction of olefins and acetylenes is demonstrated by employing catalytic amounts of ferric chloride hexahydrate (FeCl3⋅6 H2O) and aqueous…”
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Total Synthesis of MyceliothermophinsC, D, and E by Nicolaou, K C, Shi, Lei, Lu, Min, Pattanayak, Manas R, Shah, Akshay A, Ioannidou, Heraklidia A, Lamani, Manjunath

“…The total synthesis of cytotoxic polyketides myceliothermophinsE (1), C (2), and D (3) through a cascade-based cyclization to form the trans-fused decalin…”
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Abstract 518: AB801 is a highly potent and selective AXL kinase inhibitor that demonstrates significant anti-tumor activity by Paprcka, Susan Lee, Goshayeshi, Armon, Liu, Suan, Flores, Ruben, Rocha, Lauren, Leslie, Jhansi L., Miles, Dillon H., Foley, Corinne N., Qu, Shiwei, Lamani, Manjunath, Paladugu, Srinivas, Huang, Hsin-Ting, Tribewal, Nidhi, Chen, Ada, Kulusich, Joseph, Garrido-Shaqfeh, Stefan, Fabila, Patricia, Jafri, Salema, Devarajan, Anuja, Fernandez-Salas, Ester

“…Background: AXL receptor tyrosine kinase (AXL) is overexpressed in a variety of tumors and correlates with poor prognosis in cancer patients. AXL is expressed…”
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