Search Results - "Lamana, María L"
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Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells
Published in Experimental cell research (15-11-2010)“…Mesenchymal stromal cells (MSCs) have important immunosuppressive properties, but the mechanisms and soluble factors involved in these effects remain unclear…”
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Mesenchymal stem cells: biological properties and clinical applications
Published in Expert opinion on biological therapy (01-10-2010)“…In the last decade, knowledge of mesenchymal stem cells (MSCs) has evolved rapidly; their immunomodulatory properties and paracrine interactions with specific…”
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Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
Published in Nature medicine (01-09-2019)“…Fanconi anemia (FA) is a DNA repair syndrome generated by mutations in any of the 22 FA genes discovered to date 1 , 2 . Mutations in FANCA account for more…”
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Mesenchymal stromal cells enhance the engraftment of hematopoietic stem cells in an autologous mouse transplantation model
Published in Stem cell research & therapy (07-09-2015)“…Studies have proposed that mesenchymal stem cells (MSCs) improve the hematopoietic engraftment in allogeneic or xenogeneic transplants and this is probably due…”
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Enforced mesenchymal stem cell tissue colonization counteracts immunopathology
Published in npj Regenerative medicine (19-10-2022)“…Mesenchymal stem/stromal cells (MSCs) are distributed within all tissues of the body. Though best known for generating connective tissue and bone, these cells…”
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Prostaglandin E2 Plays a Key Role in the Immunosuppressive Properties of Adipose Tissue-Derived Mesenchymal Stromal Cells
Published in Blood (20-11-2009)“…Abstract 3636 Poster Board III-572 Mesenchymal stromal cells (MSCs) are multipotential non-hematopoietic cells that can be obtained from several tissues. These…”
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GRAFT-VS-LEUKEMIA EFFECT in a MOUSE MODEL of CHRONIC MYELOID LEUKEMIA
Published in Blood (20-11-2009)“…Abstract 4500 Graft-vs-Host Disease (GVHD) is a frequent and severe complication of allogeneic hematopoietic stem cell transplants (allo-HSCT), mediated by…”
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Retroviral Gene Transfer of Suicide Genes in Human T Lymphocytes: Improved Transduction Conditions for a Clinical Protocol
Published in Blood (16-11-2004)“…Aiming to control GVHD by means of the transfer of suicide genes into donor T cells, we seeked to optimise the transduction of human T cells using immobilized…”
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In vitro and in vivo susceptibility of mouse megakaryocytic progenitors to strain i of parvovirus minute virus of mice
Published in Experimental hematology (01-11-2001)“…Intranasal inoculation of the i strain of the parvovirus minute virus of mice (MVMi) into immunodeficient SCID mice induces suppression of myeloid and…”
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Systematic analysis of clinically applicable conditions leading to a high efficiency of transduction and transgene expression in human T cells
Published in The journal of gene medicine (01-01-2001)“…Background The transduction of human peripheral blood T cells with retroviral vectors constitutes an attractive approach for the correction of a number of…”
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Advances in the Gene Therapy of Patients with Fanconi Anemia
Published in Blood (29-11-2018)“…▪ Fanconi anemia (FA) is a DNA repair syndrome characterized by bone marrow failure, congenital abnormalities and cancer predisposition. Based on previous…”
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753. Lentiviral-Mediated Gene Correction of Mobilized Peripheral Blood Progenitors and Repopulating Cells from FA-A Patients
Published in Molecular therapy (01-05-2016)Get full text
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In Vitro and In Vivo Immunomodulatory Effects of Mesenchymal Stem Cells from Adipose Tissue
Published in Blood (16-11-2005)“…Previous studies have shown the immunomodulatory properties of bone marrow mesenchymal stem cells (BM-MSCs), opening the possibility of using these cells for…”
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High toxic efficiency of ricin immunotoxins specific for the T-cell antigen receptor of a human leukemia T-cell line
Published in International journal of cancer (15-04-1989)“…Immunotoxins (ITs) were prepared by covalently coupling ricin to monoclonal antibodies (MAbs) directed against: (a) 2 different epitopes of the T-cell receptor…”
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