Search Results - "Lama, Jyoti"

TFH cells regulate antibody affinity and determine the outcomes of anaphylaxis by Lama, Jyoti K., Kita, Hirohito

Get full text

T FH cells regulate antibody affinity and determine the outcomes of anaphylaxis by Lama, Jyoti K, Kita, Hirohito

Get full text

Lung-resident CD69+ST2+ TH2 cells mediate long-term type 2 memory to inhaled antigen in mice by Kobayashi, Takao, Iijima, Koji, Matsumoto, Koji, Lama, Jyoti K., Kita, Hirohito

“…Chronic airway diseases such as asthma are characterized by persistent type 2 immunity in the airways. We know little about the mechanisms that explain why…”
Get full text

A mouse model of the LEAP study reveals a role for CTLA-4 in preventing peanut allergy induced by environmental peanut exposure by Krempski, James W., Lama, Jyoti K., Iijima, Koji, Kobayashi, Takao, Matsunaga, Mayumi, Kita, Hirohito

“…A human study, Learning Early About Peanut Allergy (LEAP), showed that early introduction of peanut products decreases the prevalence of peanut allergy among…”
Get full text

Blocking the inhibitory receptor programmed cell death 1 prevents allergic immune response and anaphylaxis in mice by Lama, Jyoti K., Iijima, Koji, Kobayashi, Takao, Kita, Hirohito

“…Food allergy and acute anaphylaxis can be life-threatening. While T follicular helper (Tfh) cells play a pivotal role in the allergic immune responses, the…”
Get full text

Genetic variation in P-element dysgenic sterility is associated with double-strand break repair and alternative splicing of TE transcripts by Lama, Jyoti, Srivastav, Satyam, Tasnim, Sadia, Hubbard, Donald, Hadjipanteli, Savana, Smith, Brittny R, Macdonald, Stuart J, Green, Llewellyn, Kelleher, Erin S

“…The germline mobilization of transposable elements (TEs) by small RNA mediated silencing pathways is conserved across eukaryotes and critical for ensuring the…”
Get full text

The nuclear receptor Hr46/Hr3 is required in the blood brain barrier of mature males for courtship by Lama, Chamala, Love, Cameron R, Le, Hoa Nhu, Waqar, Marium, Reeve, Joseph L, Lama, Jyoti, Dauwalder, Brigitte

“…The blood brain barrier (BBB) forms a stringent barrier that protects the brain from components in the circulation that could interfere with neuronal function…”
Get full text

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis by Alexander, Adriana K., Rice, Edward J., Lujic, Jelena, Simon, Leah E., Tanis, Stephanie, Barshad, Gilad, Zhu, Lina, Lama, Jyoti, Cohen, Paula E., Danko, Charles G.

“…During meiotic prophase I, spermatocytes must balance transcriptional activation with homologous recombination and chromosome synapsis, biological processes…”
Get full text

Histone deacetylase 3 represses cholesterol efflux during CD4 + T-cell activation by Wilfahrt, Drew, Philips, Rachael L, Lama, Jyoti, Kizerwetter, Monika, Shapiro, Michael Jeremy, McCue, Shaylene A, Kennedy, Madeleine M, Rajcula, Matthew J, Zeng, Hu, Shapiro, Virginia Smith

“…After antigenic activation, quiescent naive CD4 T cells alter their metabolism to proliferate. This metabolic shift increases production of nucleotides, amino…”
Get full text

Mass Cytometry Reveals Distinct ILC2 Subsets During Airway Inflammation In Response to Allergen Exposure by Brooksby, Jared, Lama, Jyoti, Kobayashi, Takao, Iijima, Koji, Kita, Hirohito

Get full text

Group 2 Innate Lymphoid Cells are Involved in Development of Antigen-Specific Th2 Cells by Providing GM-CSF and Activating Dendritic Cells by Brooksby, Jared, Kobayashi, Takao, Iijima, Koji, Lama, Jyoti, Kita, Hirohito

Get full text

PD-1 blockade in T follicular helper cells protects mice from peanut allergy by promoting production of low-affinity antibodies by Lama, Jyoti K, Iijima, Koji, Kobayashi, Takao, Kita, Hirohito

“…Abstract Food allergy, such as peanut allergy can cause life-threatening anaphylaxis. While T follicular helper (Tfh) cells play a major role in production of…”
Get full text

Blocking the inhibitory receptor PD-1 prevents allergic immune response and anaphylaxis in mice by Lama, Jyoti, Iijima, Koji, Kobayashi, Takao, Kita, Hirohito

Get full text

Type 2 Innate Lymphoid Cells (ILC2s) Create Tissue Environment that Facilitates Accumulation of Antigen-specific Th2 Cells in the Lung by Kobayashi, Takao, Iijima, Koji, Lama, Jyoti, Kita, Hirohito

Get full text

Blocking the inhibitory receptor PD-1 prevents allergic immune response and anaphylaxis in mice by Lama, Jyoti K., Iijima, Koji, Kobayashi, Takao, Kita, Hirohito

“…Using mouse models, Lama et al . demonstrated that treatment with anti-PD-1 inhibits anaphylaxis in mouse models of peanut allergy. The study also suggests…”
Get full text

PD-1 regulates affinity maturation of allergen-specific antibodies and severity of peanut allergy in mice by Lama, Jyoti K, Iijima, Koji, Kobayashi, Takao, Kita, Hirohito

“…Abstract Programmed cell death-1 (PD-1), a member of the CD28 family, is critical for regulation of immune cell activation and maintenance of peripheral…”
Get full text

Skin and Airway Exposure to Allergens Promotes Development of Peanut allergy by Distinct Mechanisms in Mice by Matsunaga, Mayumi, Lama, Jyoti, Hayashi, Ryusuke, Yoshida, Yuya, Kobayashi, Takao, Iijima, Koji, Kita, Hirohito

Get full text

Oral Administration of Antigen Prevents Allergic Sensitization through Skin and Airways by Suppressing T Follicular Helper Cell Development by Masuda, Mia, Lama, Jyoti, Matsunaga, Mayumi, Yoshida, Yuya, Iijima, Koji, Kita, Hirohito

Get full text

CD69+ Th2-type CD4+ T Cells are Responsible for Long-term Memory Responses to Allergens in the Lungs by Kobayashi, Takao, Iijima, Koji, Lama, Jyoti, Kita, Hirohito

Get full text

Sensitization Through Skin and Airways Mediates Distinct Mechanisms for Anaphylaxis in Mice by Matsunaga, Mayumi, Lama, Jyoti, Hayashi, Ryusuke, Kobayashi, Takao, Iijima, Koji, Kita, Hirohito

Get full text